Advances in Virus Research

Published since 1953, Advances in Virus Research covers a diverse range of in-depth reviews providing a valuable overview of the current field of virology.In 2004, the Institute for Scientific Information released figures showing that the series has an Impact Factor of 2.576, with a half-life of 7.1 years, placing it 11th in the highly competitive category of Virology.

The Life and Times of Adenoviruses

Harold S. Ginsberg

Text

1

(11)

References

12

(3)

Role of Outer Capsid Proteins in Transmission of Phytoreovirus by Insect Vectors

Toshihiro Omura

Jin Yan

Introduction

15

(2)

Localization of Structural Proteins in Particles of Phytoreovirus

17

(1)

Role of P2 Protein in Viral Infection of Insect Vector Cells

18

(5)

Correlation between Infectivity and Presence of P2 Protein in RGDV

23

(4)

P2 Protein Allowing RDV to Adsorb to Insect Vector Cells

27

(4)

Absence of P2 Protein Expression in Transmission-Defective Isolate of RDV

31

(6)

P8 Outer Capsid Protein of RDV Involved in Viral Infection of Insect Vector Cells

37

(1)

Concluding Remarks

38

(7)

References

39

(6)

Replication of Human Hepatitis Delta Virus: Influence of Studies on Subviral Plant Pathogens

John M. Taylor

Introduction and Scope

45

(1)

Early History

46

(1)

Transmission, Epidemiology, and Pathogenesis

47

(1)

Initial Application of Molecular Virology

48

(1)

Initial Similarities to Plant Agents

49

(1)

Subsequent Molecular Virology

50

(4)

Subsequent Similarities to Plant Agents

54

(3)

Conclusions and Outlook

57

(4)

References

58

(3)

Regulation of Human Cytomegalovirus Gene Expression

Elizabeth A. Fortunato

Deborah H. Spector

Introduction

61

(2)

Viral Entry

63

(1)

Immediate Early Events Mediated by Initial Virus--Host Interaction

64

(5)

Utilization of Preexisting Nuclear Architecture by HCMV

69

(1)

Influence of Host Cell Cycle Phase on IE Gene Expression

69

(1)

Major Immediate Early Gene Expression IE1/IE2 (UL123/122)

70

(21)

Other IE Gene Products

91

(5)

Activation of Early Genes

96

(12)

Regulation of True Late Genes

108

(3)

Conclusions

111

(18)

References

112

(17)

DNA Vaccines: A Review

P. Jeff Lewis

Lorne A. Babiuk

DNA-Based Vaccines

129

(3)

Serum Kinetics and Uptake Mechanisms

132

(2)

Mechanism of Antigen Presentation

134

(5)

Adjuvancy Effects of Bacterially Derived DNA

139

(2)

Immune Response to DNA-Based Vaccines

141

(9)

Mucosal and Epidermal Delivery

150

(4)

Transdermal Delivery

154

(1)

Cytokine Modulation of Immunity to DNA-Based Vaccines

155

(9)

Safety

164

(4)

Future Directions

168

(7)

Summary

175

(14)

References

177

(12)

Epidemiological Risks from Mixed Virus Infections and Transgenic Plants Expressing Viral Genes

John Hammond

Herve Lecoq

Benjamin Raccah

Introduction

189

(3)

Mixed Infections

192

(39)

Transgenic Plants

231

(30)

Analysis of Risk and Proactive Risk Reduction

261

(22)

Concluding Remarks

283

(36)

References

289

(28)

Special Section: RESPIRATORY VIRUSES

Joseph L. Waner

Introduction

Joseph L. Waner

Text

317

(2)

Replication of Orthomyxoviruses

Agustin Portela

Thomas Zurcher

Amelia Nieto

Juan Ortin

Introduction

319

(1)

Ion Channel Protein

320

(4)

Return Ticket for RNP: Nucleocytoplasmic Transport of Influenza Genome

324

(4)

Transcription and Replication: Structure and Regulation of RNP Complex

328

(8)

Virus Assembly

336

(3)

Future Prospects

339

(10)

References

340

(9)

Influenza Vaccines: Present and Future

Kanta Subbarao

Introduction

349

(2)

Trivalent Inactivated Vaccine

351

(4)

Recombinant and Subunit Vaccines

355

(1)

Live Attenuated Influenza Vaccines

356

(6)

Future Developments in Vaccines

362

(2)

Summary

364

(11)

References

365

(10)

Influenza Neuraminidase as Target for Antivirals

Gillian M. Air

Anita A. Ghate

Stephen J. Stray

Introduction

375

(1)

Antiviral Agents

376

(9)

Structure-Based Drug Design

385

(6)

Concluding Remarks

391

(12)

References

397

(6)

Replication of Paramyxoviruses

Joseph Curran

Daniel Kolakofsky

Virion Structure and Genome Organization

403

(2)

Key Players

405

(8)

Supporting Cast

413

(3)

Genome Expression

416

(1)

Summary

417

(6)

References

418

(5)

Rational Design of Live-Attenuated Recombinant Vaccine Virus for Human Respiratory Syncytial Virus by Reverse Genetics

Peter L. Collins

Stephen S. Whitehead

Alexander Bukreyev

Rachel Fearns

Michael N. Teng

Katalin Juhasz

Robert M. Chanock

Brian R. Murphy

Introduction

423

(1)

Respiratory Syncytial Virus

424

(6)

RSV Disease

430

(1)

Immunity of RSV

431

(1)

Obstacles to Development of RSV Vaccine

432

(1)

RSV Reverse Genetics: Antigenic Subgroup A

433

(4)

Expression of Foreign Genes in Recombinant RSV

437

(1)

Gene Knockouts

438

(1)

Biologically Derived RSV Subgroup A Candidate Vaccine Viruses

439

(4)

Rational Design of Recombinant RSV Subgroup A Vaccine

443

(1)

Advantages of Recombinant DNA Method

444

(2)

Current Directions

446

(1)

Summary

446

(7)

References

447

(6)

Clinical Virology of Rhinoviruses

J. Owen Hendley

Introduction

453

(1)

Attributes of Virus and Epidemiology of Disease

454

(2)

Detection of Rhinovirus

456

(4)

Pathogenesis of Symptoms

460

(4)

Summary

464

(3)

References

465

(2)

Index

467

What is included with this book?

The New copy of this book will include any supplemental materials advertised. Please check the title of the book to determine if it should include any access cards, study guides, lab manuals, CDs, etc.

The Used, Rental and eBook copies of this book are not guaranteed to include any supplemental materials. Typically, only the book itself is included. This is true even if the title states it includes any access cards, study guides, lab manuals, CDs, etc.

FREE SHIPPING

Amazon no longer offers textbook rentals. We do!

Advances in Virus Research

Summary

Table of Contents

Supplemental Materials