Aminophosphonic and Aminophosphinic Acids Chemistry and Biological Activity

Aminophosphinic and aminoposphonic acids, synthetic analogs to natural amino acids, have attained a position of prominence in research--particularly in research involving the modification of physiological processes in living organisms.Aminophosphonic and Aminophosphinic Acids provides a comprehensive insight into the chemistry and biological activity of these compounds. Separate chapters are devoted to naturally-occurring derivatives, synthetic procedures, structural, spectroscopic and analytical aspects, metal complexes, agrochemicals, neuroactive compounds and biomedical applications and transition-state analogue enzyme inhibitors, with particular emphasis on inhibitors of HIV protease, thrombin and human collagenase. This book is a valuable source of information for researchers working with these types of compounds in biomedical and agrochemical industries and all others working with synthetic analogues of biologically important molecules.

Valery P. Kukhar is the author of Aminophosphonic and Aminophosphinic Acids: Chemistry and Biological Activity, published by Wiley. Harry R. Hudson is the author of Aminophosphonic and Aminophosphinic Acids: Chemistry and Biological Activity, published by Wiley.