Antiviral Agents and Human Viral Diseases

, by Galasso, George J.; Whitley, Richard J.; Merigan, Thomas C.

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ISBN: 9780397517091 | 0397517092
Cover: Hardcover
Copyright: 9/1/1997

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Supplemental Materials

Contributors

(2)

Preface

vii

(2)

Dedication and Acknowledgments

Basic Biology: Drug Development

(128)

1. Virus Replication: Target Functions and Events for Virus-Specific Inhibitors

(44)

Erik De Clercq

2. Pathogenesis of Viral Infection

(34)

Tony Cunningham

3. Preclinical Evaluation of Antiviral Agents

(34)

Earl R. Kern

4. Clinical Drug Development: Human Pharmacology, Safety, and Tolerance Trials

113

(16)

Paul S. Lietman

Oscar L. Laskin

Laboratory Diagnosis/Clinical Trials

129

(662)

5. Laboratory Diagnosis of Viral Infections

129

(46)

Lorraine V. Jones-Brando

Robert H. Yolken

6. Design of Clinical Trials of Treatments for HIV Infection

175

(12)

Michael D. Hughes

Victor De Gruttola

7A. Ocular Viral Infections: Herpes Simplex Virus, Epstein-Barr Virus, Adenovirus, and Poxviruses

187

(70)

Deborah Pavan-Langston

7B. Ocular Viral Infections: Varicella-Zoster Virus

229

(28)

Thomas J. Liesegang

8. Cytomegalovirus Infections in the Immunocompromised Host

257

(22)

Richard J. Whitley

Paul D. Griffiths

9. Varicella-Zoster Virus Infections

279

(26)

Richard J. Whitley

10. Herpes Simplex Virus Infections

305

(38)

Gregory J. Mertz

11. Human Papillomavirus Infections

343

(26)

Robert C. Rose

William Bonnez

Richard C. Reichman

12. Respiratory Virus Infections

369

(46)

Robert B. Couch

13. Viral Infections of the Gastrointestinal Tract

415

(44)

John J. Treanor

Raphael Dolin

14. Viral Hepatitis

459

(34)

Janice Main

Howard C. Thomas

15. Viral Infections of the Central Nervous System

493

(40)

Diane E. Griffin

16. Chronic Intrauterine and Perinatal Infections

533

(74)

Ann M. Arvin

Yvonne Maldonado

Charles A. Alford, Jr.

17. Human Immunodeficiency Viruses and Human T-Lymphotropic Viruses

607

(90)

Charles A. B. Boucher

18. Epstein-Barr Virus and Human Herpesvirus Types 6 and 7

697

(24)

Stephen E. Straus

19. Cytomegalovirus

721

(24)

Jorge A. Tavel

Scott M. Whitcup

Henry Masur

20. Hantaviruses, Filoviruses, and Other Small Lipid-Enveloped RNA Viruses Causing Hemorrhagic, Encephalititc, and Febrile Disease

745

(46)

John W. Huggins

Prevention

791

(44)

21. Immunization Against Viral Diseases

791

(44)

Gerald V. Quinnan, Jr.

Subject Index

835

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Antiviral Agents and Human Viral Diseases

Table of Contents

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