Washington Univ. School of Medicine, St. Louis. Offers current information on the basic and clinical science of the atypical antipsychotics. Explains the basic science of antipsychotic treatment and highlights various clinical applications. Also addresses the basic science of brain imaging, along with clinical applications.
Preface
iii
Contributors
vii
BASIC PHARMACOLOGY
Atypical Antipsychotic Drugs: Theories of Mechanism of Action
1
(18)
Scott Filippino
John G. Csernansky
Probing the ``Receptorome'' Unveils the Receptor Pharmacology of Atypical Antipsychotic Drugs
19
(24)
Bryan L. Roth
Neurophysiological Effects of Atypical Antipsychotic Drugs
43
(18)
Patricio O'Donnell
Behavioral Models of Atypical Antipsychotic Drug Action in Rodents
61
(32)
Mark E. Bardgett
Metabolic Regulation and Atypical Antipsychotic Drugs
93
(36)
Pierre Chue
CLINICAL EFFICACY AND TOLERABILITY
The Nosology of the Psychotic Disorders
129
(22)
Rhoshel Lenroot
John Lauriello
Acute Efficacy of Atypical Antipsychotic Drugs
151
(32)
Joseph M. Pierre
Stephen R. Marder
Long-Term Efficacy, Effectiveness, and Safety of Atypical Antipsychotic Drugs
183
(36)
Robert R. Conley
Deanna L Kelly
Assessing the Effects of Atypical Antipsychotics on the CNS Utilizing Neuroimaging
219
(20)
Laura M. Rowland
Juan R. Bustillo
Evolving Use of Atypical Antipsychotic Medications in Childhood Psychiatric Conditions
239
(34)
Donna L. Londino
Lisa Wiggins
Jennifer Dallas
Edna Stirewalt
Peter F. Buckley
Use of Atypical Antipsychotic Drugs for the Treatment of Affective Disorders
273
(38)
Martha Sajatovic
Melvin Shelton
New Targets for Antipsychotic Drugs
311
(20)
Donald C. Goff
Oliver Freudenreich
Index
331
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