The Bacterial Chromosome

Univ. of Alabama, Birmingham. Presents an examination of the mechanisms governing genetic inheritance. Covers fundamental systems required for bacterial cells to replicate chromosomes and organize and utilize genetic information. Discusses DNA replication, genetic recombination, and RNA transcription. For researchers. DNLM: Bacteria--genetics.

Contributors

vii

Preface

xi

Introduction

xiii

Allan Campbell

I. Genetic and Physical Structure

1

(166)

Where's the Beef? Looking for Information in Bacterial Chromosomes

3

(16)

John R. Roth

The Dynamic Bacterial Genome

19

(20)

Jeffrey G. Lawrence

Bacteriophages and the Bacterial Genome

39

(14)

Sherwood Casjens

Roger W. Hendrix

Global Approaches to the Bacterial Cell as an Integrated System

53

(12)

Michael T. Laub

Lucy Shapiro

Harley H. McAdams

Major Nucleoid Proteins in the Structure and Function of the Escherichia coli Chromosome

65

(68)

Reid C. Johnson

Lianna M. Johnson

John W. Schmidt

Jeffrey F. Gardner

Domain Behavior and Supercoil Dynamics in Bacterial Chromosomes

133

(22)

N. Patrick Higgins

Shuang Deng

Zhenhua Pang

Richard A. Stein

Keith Champion

Dipankar Manna

Stationary-Phase Chromosomes

155

(12)

Abraham Minsky

Roberto Kolter

II. Replication Machines

167

(108)

Replication Hits 50

169

(8)

Kenneth J. Marians

Initiation of Chromosomal Replication

177

(16)

Johanna Eltz Camara

Elliott Crooke

DNA Elongation

193

(24)

Manju M. Hingorani

Mike O'Donnell

SeqA Protein Binding and the Escherichia coli Replication Fork

217

(12)

Therese Brendler

Stuart Austin

Reinitiation of DNA Replication

229

(22)

Kenneth N. Kreuzer

Benedicte Michel

The Terminus Region of the Escherichia coli Chromosome, or, All's Well That Ends Well

251

(24)

Jean-Michel Louarn

Peter Kuempel

Francois Cornet

III. Transcription Machines

275

(72)

Overview of Transcription

277

(6)

Jeffrey Roberts

The Structure of Bacterial RNA Polymerase

283

(14)

Kati Geszvain

Robert Landick

How Transcription Initiation Can Be Regulated in Bacteria

297

(14)

Simon L. Dove

Ann Hochschild

Control of Transcription Termination and Antitermination

311

(16)

Irina Artsimovitch

mRNA Decay and Processing

327

(20)

Sidney R. Kushner

IV. Homologous Recombination-Repair Machines

347

(118)

Overview of Homologous Recombination and Repair Machines

349

(20)

Andrei Kuzminov

Franklin W. Stahl

The RecA Protein

369

(20)

Michael M. Cox

Homologous Recombination by the RecBCD and RecF Pathways

389

(16)

Maria Spies

Stephen C. Kowalczykowski

Recombination Machinery: Holliday Junction-Resolving Enzymes

405

(8)

Malcolm F. White

Dr. Jekyll and Mr. Hyde: How the MutSLH Repair System Kills the Cell

413

(18)

M.G. Marinus

Excision Repair and Bypass

431

(18)

Bernard S. Strauss

Misalignment-Mediated Mutations and Genetic Rearrangements at Repetitive DNA Sequences

449

(16)

Susan T. Lovett

V. Nonhomologous Recombination

465

(76)

DNA Transposons: Different Proteins and Mechanisms but Similar Rearrangements

467

(32)

Keith M. Derbyshire

Nigel D. F. Grindley

Potential Mechanisms for Linking Phage Mu Transposition with Cell Physiology

499

(14)

Stella H. North

Hiroshi Nakai

Chromosome Dimer Resolution

513

(12)

Francois-Xavier Barre

David J. Sherratt

Replication of Bacterial Chromosomes: No Longer Going Around in Circles

525

(16)

George Chaconas

Carton W. Chen

Index

541

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The Bacterial Chromosome

Summary

Table of Contents

Supplemental Materials

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The Bacterial Chromosome

Summary

Table of Contents

Supplemental Materials

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