- ISBN: 9783527328413 | 3527328416
- Cover: Hardcover
- Copyright: 4/11/2011
Preface | p. xi |
List of Contributors | p. xv |
New Micro and Nanotechnologies for Electrochemical Biosensor Development | p. 7 |
Introduction | p. 1 |
Carbon Nanorubes | p. 3 |
Carbon Nanorubes Used in Catalytic Biosensors | p. 4 |
Carbon Nanorubes Used in Affinity Biosensors | p. 10 |
Conductive Polymer Nanostructures | p. 15 |
Conductive Polymer Nanostructures Used in Catalytic Biosensors | p. 15 |
Conductive Polymer Nanostructures Used in Affinity Biosensors | p. 20 |
Nanoparticles | p. 23 |
Nanoparticles Used in Catalytic Biosensors | p. 23 |
Nanopartides Used in Affinity Biosensors | p. 24 |
Condusions | p. 30 |
References | p. 30 |
Advanced Nanoparticles in Medical Biosensors | p. 37 |
Introduction | p. 37 |
Nanopartides | p. 39 |
Gold Nanopartides | p. 39 |
Magnetic Nanopartides | p. 43 |
Quantum Dots | p. 44 |
Silica Based Nanopartides | p. 47 |
Dendrimers | p. 48 |
Fullerenes | p. 50 |
Condusions and Outlook | p. 52 |
References | p. 53 |
Smart Polymeric Nanofibers Resolving Biorecognition Issues | p. 57 |
Introduction | p. 57 |
Nanofibers | p. 60 |
pH-Sensitive Nanofibers | p. 61 |
Temperature-Responsive Nanofibers | p. 61 |
Electoospinning of Nanofibers | p. 62 |
Biorecognition Devices | p. 64 |
Conclusions | p. 69 |
References | p. 70 |
Fabrication and Evaluation of Nanoparticle-Based Biosensors | p. 73 |
Introduction | p. 73 |
Nanoparticle-Based Biosensors and their Fabrication | p. 74 |
Types of Nanobiosensors | p. 74 |
Electrochemical Biosensors | p. 75 |
Calorimerric Biosensors | p. 76 |
Optical Biosensors | p. 76 |
Piezoelectric Biosensors | p. 78 |
Fabrication of Biosensors | p. 78 |
Irrrmobilization of Biomolecules | p. 78 |
Conjugation of Biomolecules and Nanomaterials | p. 80 |
Newer Nanobiosensing Technologies | p. 80 |
Evaluation of Nanoparticle-Based Nanosensors | p. 82 |
Structural Characterization of Nanoparticle Based Biosensors | p. 82 |
Scartning Electron Microscopy | p. 82 |
Transmission Electron Microscopy | p. 83 |
Atomic Force Microscopy | p. 84 |
X Ray Diffraction | p. 84 |
X Ray Photoelectron Spectroscopy | p. 85 |
UV Visible Spectroscopy | p. 85 |
Functional Characterization of Nanoparticle-Based Biosensors | p. 86 |
Quartz Crystal Microbalance | p. 86 |
Ellipsometry | p. 86 |
Surface Plasmon Resonance | p. 87 |
Cyclic Voltammetry | p. 87 |
Applications of Nanoparticle-Based Biosensors | p. 88 |
Conclusions | p. 89 |
References | p. 89 |
Enzyme Based Biosensors: Synthesis and Applications | p. 95 |
Introduction | p. 95 |
Synthesis and Characterization of Biosensor Supports | p. 96 |
Carbon Nanotubes | p. 98 |
Characterization of Carbon Nanotubes | p. 98 |
Application of Carbon Nanotubes as Biosensor Supports | p. 99 |
Nanoparticles for Enzyme Immobilization | p. 100 |
General Consideration | p. 100 |
Application of Nanoparticles as Biosensor Supports | p. 101 |
Polymer Membranes | p. 102 |
Application of Enzyme-Based Biosensors | p. 104 |
Environmental Monitoring | p. 104 |
Phenolic Derivatives | p. 104 |
Pesticides | p. 105 |
Medical Diagnostics | p. 107 |
Conclusions | p. 109 |
Acknowledgments | p. 109 |
References | p. 109 |
Energy Harvesting for Biosensors Using Biofriendly Materials | p. 177 |
Introduction | p. 117 |
What is a Sensor? | p. 117 |
Why are We Moving Towards Biofriendly Materials? | p. 118 |
Why are We Moving Towards Energy Harvesting? | p. 118 |
Energy Production and. Consumption | p. 118 |
Classification of Energy-Harvesting Devices | p. 119 |
Conclusions | p. 124 |
References | p. 125 |
Carbon Nanotubes: In Vitro and In Vivo Sensing and Imaging | p. 127 |
Introduction | p. 127 |
Carbon Nanotubes: Structure, Physical and Chemical Properties, and Applications | p. 128 |
Near-IR Absorption of Carbon Nanotubes | p. 132 |
Near-IR Photoluminescence of Single-Walled Carbon Nanotubes | p. 134 |
Study Internalization Mechanism and In Vitro, In Vivo, and Long Term Fate of Carbon Nanotubes | p. 136 |
In Vitro and In Vivo Molecular Detection and Imaging | p. 138 |
Molecular Detection and Imaging Based on the Intrinsic Near-IR Fluorescence: Immunoassay | p. 138 |
Near-IR Photoluminescence Transduction Based on Band Gap Modulation of Single-Walled Carbon Nanotubes | p. 140 |
Other Sensing and Imaging Mechanisms | p. 144 |
Raman Scattering of Carbon Nanotubes | p. 145 |
Molecule Sensing and Imaging Based on Carbon Nanotube Raman Scattering | p. 147 |
Study of Internalization, In Vitro Cellular and In Vivo Tissue Biodistribution, and Long-Term Fate | p. 149 |
Conclusions and Outlook | p. 155 |
Acknowledgments | p. 155 |
References | p. 156 |
Lipid Nanoparticle Mediated Detection of Proteins | p. 161 |
Introduction to Liposomes | p. 162 |
Saturated Liposomes | p. 162 |
Detection of Antigens | p. 162 |
Detection of Viruses | p. 167 |
Detection of Enzymes | p. 169 |
Polymerized Liposomes | p. 169 |
Detection of Viruses | p. 170 |
Detection of Antigens | p. 172 |
Detection of Proteins | p. 173 |
Conclusions | p. 174 |
References | p. 174 |
Nanomaterials for Optical Imaging | p. 177 |
Introduction | p. 177 |
Doped Nanoparticles | p. 178 |
Doped Nanoparticles for In Vivo Imaging | p. 178 |
Quantum Dots | p. 180 |
Application of Quantum Dots for In Vivo Imaging | p. 182 |
Gold Nanoparticles | p. 182 |
Application of Gold Nanoparticles in Fluorescence Imaging | p. 185 |
Application of Gold Nanoparticles in Photoacoustic Imaging | p. 186 |
Lipid Based Nanoparticles | p. 188 |
Liposomes as Imaging Carriers | p. 188 |
Biomolecules | p. 190 |
Conclusions and Outlook | p. 192 |
Acknowledgments | p. 192 |
References | p. 192 |
Semiconductor Quantum Dots for Electrochemical Biosensors | p. 199 |
Introduction | p. 199 |
Attachment of Biomolecules to Quantum Dots | p. 200 |
Quantum Dot Based Redox Proteins Biosensor | p. 200 |
Glucose Oxidase Quantum Dot Based Glucose Biosensor | p. 200 |
Hemoglobin Quantum Dot Based H2O2 Biosensor | p. 204 |
Myoglobin-Quantum Dot Based H2O2 Biosensor | p. 208 |
Laccase Quantum Dot Based Ascorbic Acid Biosensor | p. 211 |
Acetylcholinesterase Quantum Dot-Based Inhibitor Biosensor | p. 211 |
Quantum Dot Based Electrochemical Biosensors of Proteins and DNA | p. 213 |
Conclusions | p. 217 |
References | p. 218 |
Functionalized Graphene for Biosensing Applications | p. 221 |
Introduction | p. 221 |
Preparation of Grapheme | p. 221 |
Functionalized Graphene with Metal Nanoparticles | p. 224 |
Glucose Biosensors Based on Graphene | p. 225 |
Immunosensors Based on Graphene | p. 228 |
Other Electrochemical Biosensors Based on Graphene | p. 229 |
Conclusions | p. 233 |
References | p. 234 |
Current Frontiers in Electrochemical Biosensors Using Chitosan Nanocomposites | p. 237 |
Introduction | p. 237 |
Chitosan | p. 238 |
Chitosan Nahocomposite-Based Electrochemical Biosensors | p. 240 |
Chitosan Nanocomposite Based Amperometric Biosensors | p. 240 |
Chitosan Nanocomposite Based Potentiometric Biosensors | p. 242 |
Chitosan Nanocomposite Based Conductimetric Biosensors | p. 244 |
Conclusions and Future Aspects | p. 245 |
References | p. 245 |
Nanomaterials as Promising DNA Biosensors | p. 247 |
Introduction | p. 247 |
Nanomaterials as Signal Amplifiers for Hybridization | p. 248 |
Nanoparticles | p. 248 |
Gold Nanoparticles | p. 249 |
Silver Nanoparticles | p. 249 |
Cadmium Sulfide Nanoparticles | p. 250 |
Quantum Dots | p. 250 |
Carbon Nanotube Based Electrochemical DNA Sensors | p. 251 |
Conclusions | p. 252 |
References | p. 253 |
Nanocomposites and their Biosensor Applications | p. 255 |
Introduction | p. 255 |
Nanocomposites | p. 256 |
Ceramic Matrix Nanocomposites | p. 257 |
Metal Matrix Nanocomposites | p. 258 |
Polymer Matrix Nanocomposites | p. 258 |
Biosensors | p. 259 |
Types of Biosensors | p. 261 |
Electrochemical | p. 262 |
Potentiometric | p. 262 |
Conductrmetric | p. 262 |
Amperometric | p. 263 |
Thermal Detection | p. 263 |
Ion Sensitive | p. 263 |
Optical Detection | p. 263 |
Resonant | p. 264 |
Biosensors Applications | p. 264 |
Nanocomposites for Biosensor Applications | p. 264 |
Conclusions | p. 266 |
References | p. 266 |
Index | p. 269 |
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