Cancer Prevention and Screening Concepts, Principles and Controversies

Winner of the Council Chair's Choice Award at the 2019 British Medical Association Awards.

Cancer Prevention and Screening offers physicians and all clinical healthcare professionals a comprehensive, useful source of the latest information on cancer screening and prevention with both a global and a multidisciplinary perspective.

• Includes background information on epidemiology, cancer prevention, and cancer screening, for quick reference 
• Offers the latest information for clinical application of the most recent techniques in prevention and screening of all major and many lesser cancer types 
• Emphasises the importance of multidisciplinary teamwork in cancer screening 
• Highlights frequent dilemmas and difficulties encountered during cancer screening 
• Provides clear-cut clinical strategies for optimal patient education, communication, and compliance with cancer prevention techniques

ROSALIND A. EELES, MA (Cantab), PhD, FRCP, FRCR, FMedSCI is Professor of Oncogenetics and Team Leader in Oncogenetics at The Institute of Cancer Research and an Honorary Consultant in Cancer Genetics and Clinical Oncology at The Royal Marsden NHS Foundation Trust, London, UK

CHRISTINE D. BERG, MD is Special Advisor to the Director, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Maryland, USA

JEFFREY S. TOBIAS, MA (Cantab), MD, FRCP, FRCR is Professor of Cancer Medicine at the Department of Oncology, University College London, and Honorary Consultant at University College Hospital Foundation Trust, London, UK

List of contributors vii

Foreword xi

Prologue xiii

1 Global perspectives surrounding cancer prevention and screening 1
Peter David Sasieni and Donald Maxwell Parkin

2 Public health perspectives surrounding cancer prevention and screening: The Ontario edition 19
Linda Rabeneck and Arlinda Ruco

3 Cancer screening: A general perspective 31
Otis W. Brawley

4 The balance of cancer screening risks and benefits 41
Julietta Patnick

5 Cancer screening issues in black and ethnic minority populations 51
Otis W. Brawley

6 Public awareness of cancer screening 57
Jane Wardle and Laura A.V. Marlow

7 Public understanding of cancer prevention 69
Jessica Kirby and Sarah Woolnough

8 Cervical cancer screening: An exemplar of a population screening programme and cervical cancer prevention 81
Albert Singer and Ashfaq Khan

9 Prevention of and screening for anal cancer 101
Andrew E. Grulich Richard J. Hillman and Isobel M. Poynten

10 The prevention of breast cancer 111
Anthony Howell Michelle N. Harvie Sacha J. Howell Louise S. Donnelly and D. Gareth Evans

11 Breast cancer: Population and targeted screening 129
Fiona J. Gilbert Fleur Kilburn‐Toppin Valerie D.V. Sankatsing and Harry J de Koning

12 Prostate cancer prevention 145
Evan Kovac Andrew J. Stephenson Margaret G. House Eric A. Klein, and Howard L. Parnes

13 Population screening for prostate cancer 171
Richard J. Bryant Monique J. Roobol and Freddie C. Hamdy

14 Colon cancer prevention 183
John Burn and Harsh Sheth

15 Colon cancer screening 203
David F. Ransohoff

16 Lung cancer prevention 217
Jonathan M. Samet

17 Lung cancer screening 237
Christine D. Berg Kwun M. Fong and Henry M. Marshall

18 Mesothelioma: Screening in the modern age 257
Joanna Sesti Sabina Musovic Jessica S. Donington and Harvey I. Pass

19 Skin cancer prevention and screening 275
Mark Elwood and Terry Slevin

20 Screening and prevention of oral cancer 295
Apurva Garg Pankaj Chaturvedi and Rajiv Sarin

21 Oesophageal cancer 309
Timothy J. Underwood

22 Hepatocellular carcinoma: Prevention and screening 317
Aileen Marshall and Tim Meyer

23 Ovarian cancer prevention and screening 331
Aleksandra Gentry‐Maharaj Michelle Griffin and Usha Menon

24 Screening for testicular cancer 349
Kevin Litchfield Clare Turnbull and Robert A. Huddart

25 Issues in paediatric cancers 361
Jonah Himelfarb and David Malkin

26 Obesity and dietary approaches to cancer prevention 381
Andrew G. Renehan

27 Risk profiling for cancer prevention and screening – lessons for the future 403
Rosalind A. Eeles Paul Pharoah Alison Hall Susmita Chowdhury,and Hilary Burton

28 Cancer prevention and screening: Advances to carry forward 417
Christine D. Berg Rosalind A. Eeles and Jeffrey S. Tobias

Index 425

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