Clinical Bioinformatics

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ISBN: 9781588297914 | 1588297918
Cover: Hardcover
Copyright: 1/9/2008

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With the ever-increasing volume of information in clinical medicine, researchers and health professionals need computer-based storage, processing and dissemination. In this book, leading experts in the field provide a series of articles focusing on software applications used to translate information into outcomes of clinical relevance. This book is the perfect guide for researchers and clinical scientists working in this emerging "omics" era.

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Preface	p. v
Contributors	p. ix
In Silico Gene Discovery	p. 1
Whole Genome-Wide Association Study Using Affymetrix SNP Chip: A Two-Stage Sequential Selection Method to Identify Genes That Increase the Risk of Developing Complex Diseases	p. 23
Utilizing HapMap and Tagging SNPs	p. 37
Measuring the Effects of Genes and Environment on Complex Traits	p. 55
Microarrays-Planning Your Experiment	p. 71
Clinical Uses of Microarrays in Cancer Research	p. 87
Microarrays-Analysis of Signaling Pathways	p. 115
Microarrays-Identifying Molecular Portraits for Prostate Tumors with Different Gleason Patterns	p. 131
Microarrays for the Study of Viral Gene Expression During Human Cytomegalovirus Latent Infection	p. 153
Computer-Assisted Reading of DNA Sequences	p. 177
Evaluating DNA Sequence Variants of Unknown Biological Significance	p. 199
Developing a DNA Variant Database	p. 219
Protein Comparative Sequence Analysis and Computer Modeling	p. 245
Identification and Characterization of Microbial Proteins Using Peptide Mass Fingerprinting Strategies	p. 257
Statistical Analysis of Image Data Provided by Two-Dimensional Gel Electrophoresis for Discovery Proteomics	p. 271
Online Resources for the Molecular Contextualization of Disease	p. 287
Web-Based Resources for Clinical Bioinformatics	p. 309
Developing Decision Support Systems in Clinical Bioinformatics	p. 331
eConsulting	p. 353
Index	p. 375
Table of Contents provided by Ingram. All Rights Reserved.

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Clinical Bioinformatics

Summary

Table of Contents

Supplemental Materials

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Clinical Bioinformatics

Summary

Table of Contents

Supplemental Materials

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