Clinical Hematology and Fundamentals of Hemostasis

Unit 1. Introduction to Clinical Hematology
1. Morphology of Human Blood and Marrow Cells: Hematopoiesis
2. Bone Marrow
3. The Red Blood Cell: Structure and Function
4. Anemia: Diagnosis and Clinical Considerations
5. Evaluation of Cell Morphology and Introduction to Platelet and White Cell Morphology

Unit 2. Anemias
6. Iron Metabolism and Hypochromic Anemias
7. Megaloblastic Anemias
8. Aplastic Anemia Including Pure Red Cell Aplasia and Congenital Dyserythropoietic Anemia and Paroxysmal Noctural Hemoglobinuria (PNH)
9. Introduction to Hemolytic Anemias: Intracorpuscular Defects: I. Hereditary Defects of the Red Cell Membrane
10. Hemolytic Anemias: Intracorpuscular Defects: II. Hereditary Enzyme Deficiencies
11. Hemolytic Anemias: Intracorpuscular Defects: III. The Hemoglobinopathies
12. Hemolytic Anemias: Intracorpuscular Defects: IV. Thalassemia
13. Hemolytic Anemias: Extracorpuscular Defects
14. Hypoproliferative Anemia: Anemia Associated with Systemic Diseases

Unit 3. White Blood Cell Disorders
15. Cell Biology, Disorders of Neutrophils, Infectious Mononucleosis, and Reactive Lymphocytosis
16. Introduction to Leukemia and the Acute Leukemias
17. Chronic Myeloproliferative Disorders: I. Chronic Myclogenous Leukemia
18. Chronic Myeloproliferative Disorders: II. Polycythemia Vera, Essential Thrombocythemia, and Idiopathic Myelofibrosis
19. Myelodysplastic Syndromes (MDS)
20. Chronic Lymphocytic Leukemia and Related Lymphoproliferative Disorders
21. The Lymphomas
22. Mutiple Myeloma and Related Plasma Cell Disoders
23. Lipid (Lysosomal) Storage Diseases and Histiocytosis

Unit 4. Hemostasis and Introduction to Thrombosis
24. Introduction to Hemostasis
25. Disorders of Primary Hemostasis: Quantitative and Qualitative Platelet Disorders and Vascular Disorders
26. Disorders of Plasma Clotting Factors
27. Interaction of the Fibrinolytic, Coagulation, and Kinin Systems: Disseminated Intravascular Coagulation; and Related Pathology
28. Introduction to Thrombosis and Anticoagulant Therapy

Unit 5 Laboratory Methods
29. Quality Control in the Hematology Laboratory
30. Body Fluid Examination: The Qualitative, Quantitative, and Morphologic Analysis of Serous, Cerebrospinal, and Synovial Fluids
31. Hematology Methods
32. Principles of Automated Differential Analysis
33. Coagulation Procedures
34. Applications of Flow Cytometry to Hematology and Hemostasis
35. Molecular Diagnostic Techniques in Hematopathology
36. Special Stains/Cytochemistry

Answers to Chapter Review Questions
Glossary
Bibliography

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