Clinical Manual for the Treatment of Autism

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ISBN: 9781585622221 | 1585622222
Cover: Paperback
Copyright: 9/1/2007

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Reflecting tremendous gains over the past decade in our understanding of the causes of autism, Clinical Manual for the Treatment of Autism meets the increasing need for clear, up-to-date, and evidence-based treatment. Internationally known researchers-who are also skilled in treating patients with autism-share treatment approaches they have either developed or thoroughly tested for safety and efficacy.

Contributors	p. xiii
Foreword	p. xix
Clinical Diagnosis of Autism	p. 1
Historical Background	p. 1
The DSM-IV Field Trial	p. 8
Alternative Approaches to Classification	p. 9
Areas of Diagnostic Controversy	p. 13
Clinical Diagnostic Assessment and Differential Diagnosis	p. 17
Conclusions	p. 21
References	p. 22
Evaluation and Testing for Autism	p. 27
Diagnostic Evaluations	p. 30
Assessment of Core Autism Spectrum Disorder Domains	p. 38
Other Critical Domains for Assessment	p. 40
Conclusions	p. 44
References	p. 44
Treatment of Autism With Selective Serotonin Reuptake Inhibitors and Other Antidepressants	p. 51
Mechanism of Action	p. 52
Rationale for Use of Selective Serotonin Reuptake Inhibitors in the Treatment of Autism	p. 53
Serotonin Reuptake Inhibitors: Clomipramine	p. 55
Selective Serotonin Reuptake Inhibitors	p. 57
Serotonin-Norepinephrine Reuptake Inhibitors	p. 64
Conclusions and Future Directions	p. 65
References	p. 76
Treatment of Autism With Anticonvulsants and Mood Stabilizers	p. 81
Comorbid Disorders in Autism	p. 82
Mechanism of Action of Anticonvulsants	p. 84
Clinical Evidence for Anticonvulsant Efficacy in Autism	p. 85
Conclusions	p. 92
References	p. 93
Treatment of Autism With Antipsychotics	p. 99
Mechanism of Action	p. 100
Rationale for the Use of Antipsychotics in Autism	p. 100
Conventional Antipsychotics	p. 101
Atypical Antipsychotics	p. 104
Conclusions	p. 116
References	p. 116
Cholinesterase Inhibitor Therapy in Patients With Autism Spectrum Disorders	p. 121
History of Cholinesterase Inhibitors	p. 122
Cholinergic Mechanisms in Autism	p. 123
Treatment Experience With Cholinesterase Inhibitors in Autism	p. 124
Conclusions	p. 127
References	p. 128
Stimulants and Nonstimulants in the Treatment of Hyperactivity in Autism	p. 131
Stimulants	p. 134
Alpha-Adrenergic Agonists	p. 137
Antidepressants	p. 140
Amantadine	p. 142
Naltrexone	p. 143
Antipsychotics	p. 144
Conclusions	p. 147
References	p. 147
Applied Behavior Analysis in the Treatment of Autism	p. 153
Research on Applied Behavior Analysis and Models of Service Delivery	p. 155
Applied Behavior Analysis Providers	p. 161
Applied Behavior Analysis Intervention Methods	p. 161
Manuals and Curriculum Guides	p. 169
Conclusions	p. 169
References	p. 170
The Developmental Individual-Difference, Relationship-Based (DIR/Floortime) Model Approach to Autism Spectrum Disorders	p. 179
The DIR/Floortime Model	p. 180
The DIR/Floortime Assessment	p. 182
Core Psychological Deficit in Autism and the Developmental Pathways to Joint Attention, Pattern Recognition, Theory of Mind, Language, and Thinking	p. 183
The DIR/Floortime Intervention Program	p. 189
Selected Research on the DIR/Floortime Model and Outcome Studies	p. 196
Summary	p. 205
References	p. 205
Educational Approaches for Autism-TEACCH	p. 211
Background and Structure of TEACCH	p. 212
Core Principles and Values	p. 214
Applications of TEACCH Methods and Strategies	p. 217
Treatment Effectiveness	p. 226
Conclusions	p. 229
References	p. 229
Peer Relationships of Children With Autism: Challenges and Interventions	p. 235
Peer Interaction Challenges for Children With Autism	p. 236
Peer Relations, Social Acceptance, and Inclusion	p. 239
Peer Interventions and Autism	p. 241
Predictors and Correlates of Treatment Response	p. 249
Outcomes of Peer Interventions	p. 250
Conclusions	p. 250
References	p. 251
Complementary and Alternative Therapies for Autism	p. 259
Helping Parents Make Informed Choices About CAM Treatments	p. 260
Specific CAM Therapies	p. 263
Conclusions	p. 280
References	p. 280
Promising New Avenues of Treatment and Future Directions for Patients With Autism	p. 289
Pharmacological Treatments	p. 290
Educational and Psychosocial Interventions	p. 294
Advocacy	p. 294
References	p. 295
Index	p. 299
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Clinical Manual for the Treatment of Autism

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