Clinical Research Methodology and Evidence-Based Medicine: The Basics

This is an introduction for novices to the fields of research methodology and evidence-based medicine. Worldwide there are many practicing clinicians or junior faculty members who desire to do simple projects related to clinical research but they hesitate for lack of appropriate training or experience. Similarly, the concept of evidence-based medicine has gathered international momentum and many seek to know how to practice it.There are few books written that focus on both of these two related areas, especially from the perspective of teaching the fundamentals. The primary author and his collaborating contributors all have extensive first-hand experience in practicing and teaching the approaches they write about. An international group of educators affiliated to renowned academic medical centres have put together this work, which will be welcomed by trainees and practitioners alike.Contents1. Introduction 2. Introduction to Biostatistics 3. Research Methodology 4. An Introduction to Medical Decision-making 5. Sources of Evidence and How to Use Them 6. An Overview of Evidence-based Medicine (EBM) and Critical Appraisal 7. EBM and Therapy 8. EBM and Diagnosis 9. EBM and Prognosis 10. EBM and Economic Analysis 11. Translating EBM into Practice 12. Ethics in Healthcare 13. Evidence-based Medicine and Medical Informatics