Clinical Transfusion Medicine

Brown Univ., Providence, RI. Discusses clinical problems as they relate to decision making regarding blood transfusion. For residents, students, nurse practitioners, and physician assistants. Chapters are thumbed-tabbed. Trim size: 8 x 5 inches. Wire-spiral binding. DNLM: Blood Transfusion Handbooks.

Section A: General

Introduction

1

(3)

Allogeneic Blood Products

4

(5)

Autologous Blood Products

9

(5)

Predeposit Autologous Blood (PAD)

9

(1)

Preoperative Hemodilution or Preoperative Apheresis

10

(1)

Intraoperative Salvage

11

(1)

Postoperative Salvaged Blood

11

(1)

Autologous Stem Cells

12

(2)

Epidemiology of Blood Transfusion

14

(2)

Informed Consent and Explanation of Blood Options

16

(4)

The ABO and Rhesus System

20

(3)

Compatibility Testing and the Importance of Proper Recipient Identification

23

(5)

The Administration of Blood Products

28

(3)

Section B: Surgery

Blood Transfusion in Surgery I: Ordering Practices and Transfusion Styles

31

(4)

Blood Transfusion in Surgery II: Cardiac and Vascular Surgery

35

(4)

Blood Transfusion in Surgery III: Orthopedic and Urologic Surgery

39

(4)

Blood Transfusion in Surgery IV: Blood Transfusion in Solid Organ Allografts

43

(4)

Kidney Transplantation

44

(1)

Liver Transplantation

45

(1)

Heart Transplantation

46

(1)

Lung Transplants

46

(1)

Blood Transfusion in Surgery V: General Surgery

47

(4)

Blood Transfusion in Surgery VI: Trauma and Massive Blood Transfusion

51

(4)

Section C: Medicine

Blood Transfusion in Medicine I: Cancer

55

(4)

Hematological Malignancies in Adults

55

(2)

Pediatric Malignancies

57

(2)

Blood Transfusion in Medicine II: Bone Marrow Transplantation

59

(4)

Autologous Stem Cell Transplants

59

(1)

Allogeneic Stem Cell Transplants

60

(3)

Blood Transfusion in Medicine III: Hereditary Anemias

63

(5)

Sickle Cell Syndromes

63

(3)

Thalassemic States

66

(2)

Blood Transfusion in Medicine: IV: Renal Disease

68

(4)

Blood Transfusion in Medicine V: Patients with Acute Gastrointestinal Bleeding

72

(2)

Blood Transfusion in Medicine VI: Patients Infected with Human Immunodeficiency Virus

74

(2)

Blood Transfusion in Medicine VII: Hereditary and Acquired Bleeding Disorders

76

(6)

Hereditary Bleeding Disorders

76

(2)

Acquired Bleeding Disorders

78

(4)

Blood Transfusion in Medicine VII: Autoantibodies to Red Cells and Platelets

82

(5)

Red Cell Autoantibodies

82

(2)

Platelet Autoantibodies

84

(3)

Blood Transfusion in Medicine IX: Using Drugs to Reduce Blood Transfusion

87

(4)

Hormones or Hormone Derivatives

87

(4)

Blood Transfusion in Obstetrics

91

(4)

Fetal and Neonatal Transfusion

95

(4)

Fetal Transfusions

95

(1)

Neonatal Transfusions

95

(1)

Neonatal Thrombocytopenia

96

(3)

Section D: Appropriate Prescribing

Clinical Decisions and Response Monitoring: Triggers, Targets, Functional Reserve and Threshold of Effect

99

(4)

Red Blood Cells: Indications and Dosing

103

(4)

Platelets: Indications and Dosing

107

(5)

Plasma and Cryoprecipitate: Indications and Dosing

112

(5)

Plasma

112

(5)

Leukocytes, Indications and Dosage

117

(3)

Blood Derivatives: Indications and Dosage

120

(3)

Section E: Complications

Acute Complications of Blood Transfusion

123

(8)

Life Threatening Acute Complications

123

(5)

Non-Life Threatening Acute Complications of Blood Transfusion

128

(3)

Delayed and Late Complications of Blood Transfusion

131

(4)

Delayed Blood Transfusion Reactions

131

(2)

Late Complications

133

(2)

Blood Transfusion Transmitted Infections I: Viruses

135

(5)

Viruses

135

(5)

Blood Transfusion Transmitted Infections II: Bacteria, Protozoa, Helminths and Prions

140

(5)

Section F: Special Products

Special Blood Product I: Leukoreduced and Washed Blood Products

145

(4)

Special Blood Products II: Irradiated Blood Products and Transfusion Associated Graft Versus Host Disease

149

(4)

Special Blood Products III: Cytomegalic Virus Low Risk Blood Products and the Prevention of Primary CMV Disease

153

(3)

Special Blood Product IV: Frozen Blood

156

(2)

Special Blood Products V: Therapeutic Phlebotomy, Apheresis and Photopheresis

158

(5)

Therapeutic Phlebotomy

158

(1)

Therapeutic Apheresis

159

(3)

Photopheresis

162

(1)

Blood Transfusion in the 21st Century

163

(2)

Appendix

165

(2)

Index

167

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Clinical Transfusion Medicine

Summary

Table of Contents

Supplemental Materials

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Clinical Transfusion Medicine

Summary

Table of Contents

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