Univ. of Exeter, U.K. Research for investigators. 41 contributors, 19 U.S.
Preface
iii
(6)
Contributors
ix
PART I. OVERVIEW
1
(162)
1 Introduction to the Hematopoietic System
1
(34)
John M. Garland
Claudius E. Rudin
2 Surrogate Assays for Hematopoietic Stem Cell Activity
35
(14)
Ivan Bertoncello
Gillian B. Bradford
3 Receptors for Hematopoietic Regulators
49
(22)
Douglas J. Hilton
4 Regulation of the Cell Cycle by Kinases and Cyclins
71
(26)
Arthur B. Pardee
Khandan Keyomarsi
Qing Ping Dou
5 Gene Organization and Regulation
97
(10)
David S. Latchman
6 Cytokines and Apoptosis: The Mechanism of Regulation of Cell Death
107
(10)
Mary K. L. Collins
Abelardo Lopez-Rivas
7 Hematopoietic Microenvironments
117
(16)
Michael W. Long
8 Extracellular Matrix- and Membrane-Bound Cytokines
133
(12)
M. Y. Gordon
9 Transfection of Stem Cells and Gene Therapy
145
(18)
Robert C. Moen
PART II. COLONY-STIMULATING FACTOR
163
(258)
10 Granulocyte-Macrophage Colony-Stimulating Factor and Its Receptor
163
(40)
John E. J. Rasko
11 Granulocyte Colony-Stimulating Factor
203
(24)
Andrew W. Roberts
Nicos A. Nicola
12 Human Interleukin-3: An Overview
227
(28)
Yu-Chung Yang
13 Macrophage Colony-Stimulating Factor
255
(36)
Malcolm A. S. Moore
14 Erythropoietin
291
(24)
Stephanie S. Watowich
15 The Role of Interleukin-4 in Normal and Malignant Human Hematopoiesis
315
(32)
Sem Saeland
Jacques Banchereau
16 Hematopoietic Effects of Interleukin-1
347
(22)
James R. Zucali
Claire M. Dubois
Joost J. Oppenheim
17 Kit-Ligand-Stem Cell Factor
369
(36)
Peter Besmer
18 Interleukin-5
405
(16)
Colin J. Sanderson
PART III. CYTOKINES
421
(140)
19 Macrophage Inflammatory Protein-1XXX
421
(24)
Mark A. Plumb
Eric Wright
20 Transforming Growth Factor-XXX, Tumor Necrosis Factor-XXX, and Macrophage Inflammatory Protein-1XXX Are Bidirectional Regulators of Hematopoietic Cell Growth
445
(22)
Jonathan R. Keller
Francis W. Ruscetti
Krzysztof J. Grzegorzewski
Robert H. Wiltrout
Stephen H. Bartelmez
Ewa Sitnicka
Sten Eirik W. Jacobsen
21 Leukemia Inhibitory Factor
467
(48)
Paul M. Waring
22 Interleukin-12 in Hematopoiesis
515
(18)
Sten Eirik W. Jacobsen
Erlend B. Smeland
23 Ex Vivo Expansion of Hematopoietic Stem and Progenitor Cells
533
(14)
Ahmad-Samer Al-Homsi
Peter J. Quesenberry
24 Clinical Use of Cytokines
547
(14)
Darryl W. Maher
Index
561
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