Computer Modeling in Bioengineering

Bioengineering is a broad-based engineering discipline that applies engineering principles and design to challenges in human health and medicine, dealing with bio-molecular and molecular processes, product design, sustainability and analysis of biological systems. Applications that benefit from bioengineering include medical devices, diagnostic equipment and biocompatible materials, amongst others.Computer Modeling in Bioengineering offers a comprehensive reference for a large number of bioengineering topics, presenting important computer modeling problems and solutions for research and medical practice. Starting with basic theory and fundamentals, the book progresses to more advanced methods and applications, allowing the reader to become familiar with different topics to the desired extent. It includes unique and original topics alongside classical computational modeling methods, and each application is structured to explain the physiological background, phenomena that are to be modeled, the computational methods used in the model, and solutions of typical cases. The accompanying software contains over 80 examples, enabling the reader to study a topic using the theory and examples, then run the software to solve the same, or similar examples, varying the model parameters within a given range in order to investigate the problem at greater depth. Tutorials also guide the user in further exploring the modeled problem; these features promote easier learning and will help lecturers with presentations.Computer Modeling in Bioengineering includes computational methods for modelling bones, tissues, muscles, cardiovascular components, cartilage, cells and cancer nanotechnology as well as many other applications. It bridges the gap between engineering, biology and medicine, and will appeal not only to bioengineering students, lecturers and researchers, but also medical students and clinical researchers.

Milos Kojic, Senior Research Scientist, Harvard School of Public Health, Harvard University, Boston, MA
Milos Kojic is professor of mechanical engineering, University of Kragujevac, Serbia; and Senior Research Scientist, Harvard School of Public Health, Harvard University, Boston. He is one of the leading scientists in computational mechanics. He has published, as the author or mainly the first author, around 60 journal papers, among which are papers in leading international journals, as International Journal for Numerical Methods in Engineering, Computer Methods in Applied Mechanics and Engineering, Comp. Mech., International Journal of Vehicle Design, Appl. Mech., Computers and Struct, Biophysical Journal, Phys. Rev., etc. His research spans from the finite element method in general, methods of inelastic analysis of solids and structures, field and coupled problems, to biomechanics, and recently molecular dynamics and discrete particle methods.

Nenad Filipovic, Faculty of Mechanical Engineering, Serbia and Montenegro
Nenad Filipovic is associate professor of mechanical engineering, University of Kragujevac,? Serbia; and research associate at Harvard School of Public Health, Harvard University, Boston. He is young scientist and author and co-author of a number of papers in international journals.

Boban Stojanovic, University of Kragujevac, Serbia and Montenegro
Boban Stojanovic is a Ph.D. candidate in Bioengineering at Multidisciplinary Graduate Studies of University of Kragujevac. He received his B.S. at Faculty of Mechanical Engineering of University of Kragujevac, as first in his generation and most talented students. During his studies he participated significantly in development of the finite element program PAK.

Akira Tsuda, Boston, MA
Akira Tsuda is Principal Research Scientist, in the Physiology Program, Harvard School of Public Health. He is an expert in biofluid mechanics, specifically in the field of respiratory flow and aerosol physiology. He has published extensively in this field and in the related field. He has been the principal investigator of several research projects, including international bioengineering projects/p>

Nikola Kojic, Cambridge, MA, USA
Nikola Kojic is a Ph.D. candidate in the Harvard-MIT Division of Health Sciences and Technology. He received his M.S. in Mechanical Engineering in 2003 from MIT, working on synthetic and natural spider silk. Specifically, his focus was on the application of computational models to synthetic and natural spider silk fiber spinning.

Theoretical Background of Computational Methods
Notation - Matrices and Tensors
Matrix representation of mathematical objects
Basic relations in matrix algebra
Definition of tensors and some basic tensorial relations
Vector and tensor differential operations and integral theorems
Examples
Fundamentals of Continuum Mechanics
Definitions of stress and strain
Linear elastic and viscoelastic constitutive relations
Principle of virtual work
Nonlinear continuum mechanics
Heat Transfer, Diffusion, Fluid Mechanics, and Fluid Flow through Porous Deformable Media
Heat conduction
Diffusion
Fluid flow of incompressible viscous fluid with heat and mass transfer
Fluid flow through porous deformable media
Fundamentals of Computational Methods
Isoparametric Formulation of Finite Elements
Introduction to the finite element method
Formulation of 1D finite elements and equilibrium equations
Three-dimensional (3D) isoparametric finite element
Two-dimensional (2D) isoparametric finite elements
Isoparametric shell finite element for general 3D analysis
Dynamic Finite Element Analysis
Introduction to dynamics of structures
Differential equations of motion
Integration of differential equations of motion
System frequencies and modal shapes
Examples
Introduction to Nonlinear Finite Element Analysis
Introduction
Principle of virtual work and equilibrium equations in nonlinear incremental analysis
Examples
Finite Element Modeling of Field Problems
Introduction
Heat conduction
Diffusion
Fluid flow with heat and mass transfer
FE equations for modeling large change of fluid domain - arbitrary Lagrangian-Eulerian (ALE) formulation
Solid-fluid interaction
Fluid flow through porous deformable media
Discrete Particle Methods for Modeling of Solids and Fluids
Molecular dynamics
Dissipative particle dynamics (DPD) method
Multiscale modeling, coupling DPD-FE for fluid flow
Smoothed particle hydrodynamics (SPH)
Element-free Galerkin (EFG) method
Computational Methods in Bioengineering
Introduction to Bioengineering
The subject and scope of bioengineering
The role of computer modeling in bioengineering
Bone Modeling
The structure and forms of bones
The mechanical properties of bone and FE modeling
Bone fracture - medical treatment and computer modeling
Internal fixation of hip fracture - two solutions and computer models
Biological Soft Tissue
Introduction to mechanics of biological tissue
Modeling methods for isotropic tissue
Examples
Skeletal Muscles
Introduction
Muscle modeling
Examples
Blood Flow and Blood Vessels
Introduction to the cardiovascular system
Methods of modeling blood flow and blood vessels
Human aorta
Abdominal aortic aneurysm (AAA)
Blood flow through the carotid artery bifurcation
Femoral artery with stent
Blood flow in venous system
Heart model
Modeling Mass Transport and Thrombosis in Arteries
Introduction
Modeling thrombosis by continuum-based methods
Modeling of thrombosis by DPD
Cartilage Mechanics
Introduct
Table of Contents provided by Publisher. All Rights Reserved.

What is included with this book?

The New copy of this book will include any supplemental materials advertised. Please check the title of the book to determine if it should include any access cards, study guides, lab manuals, CDs, etc.

The Used, Rental and eBook copies of this book are not guaranteed to include any supplemental materials. Typically, only the book itself is included. This is true even if the title states it includes any access cards, study guides, lab manuals, CDs, etc.

FREE SHIPPING

Rent More, Save More! Use code: BBRENTAL

5% off 1 book, 7% off 2 books, 10% off 3+ books

Computer Modeling in Bioengineering Theoretical Background, Examples and Software

Summary

Author Biography

Table of Contents

Supplemental Materials