Concepts of Alzheimer Disease: Biological,

As the essays in this volume show, conceptualizing dementia has always been a complex process. With contributions from noted professionals in psychiatry, neurology, molecular biology, sociology, history, ethics, and health policy, Concepts of Alzheimer Disease looks at the ways in which Alzheimer disease has been defined in various historical and cultural contexts. The book covers every major development in the field, from the first case described by Alois Alzheimer in 1907 through groundbreaking work on the genetics of the disease. Essays examine not only the prominent role that biomedical and clinical researchers have played in defining Alzheimer disease, but also the ways in which the perspectives of patients, their caregivers, and the broader public have shaped concepts.

Peter J. Whitehouse, M.D., Ph.D., is a professor of neurology, psychiatry, neuroscience, psychology, nursing, organizational behavior, and biomedical ethics at the Fairhill Center for Aging, Case Western Reserve University, and a founding director of the Alzheimer Center at the University Hospitals of Cleveland. Konrad Maurer, M.D., Ph.D., is a professor in and head of the Department of Psychiatry and Psychotherapy, and director of the Clinic for Psychiatry, at the Johann Wolfgang Goethe University. Jesse F. Ballenger, Ph.D., is a post-doctoral fellow at the Institute of the History of Medicine at the Johns Hopkins University.

Preface

xi

Acknowledgments

xvii

List of Contributors

xix

PART I The Cases of Auguste D. and Johann F.

Origins of the Modern Concept of Alzheimer Disease

1

(4)

Auguste D.: The History of Alois Alzheimer's First Case

5

(25)

Konrad Maurer

Stephan Volk

Hector Gerbaldo

Johann F.: The Historical Relevance of the Case for the Concept of Alzheimer Disease

30

(17)

Hans-Jurgen Moller

Manuel B. Graeber

PART II From Alzheimer to the Present

47

(78)

Neurofibrillary Changes: The Hallmark of Alzheimer Disease

53

(19)

Heiko Braak

Eva Braak

Contributions of German Neuroscience to the Concept of Alzheimer Disease

72

(11)

Hans Forstl

Beyond the Characteristic Plaques and Tangles: Mid-Twentieth-Century U.S. Psychiatry and the Fight Against Senility

83

(21)

Jesse F. Ballenger

The Rediscovery of Alzheimer Disease During the 1960s and 1970s

104

(11)

Robert Katzman

Katherine L. Bick

The History of the Genetics of Alzheimer Disease

115

(10)

Daniel A. Pollen

PART III Alzheimer Disease as a Social and Cultural Entity

125

(80)

Alzheimer Disease: Epistemological Lessons from History?

129

(29)

Rob J. M. Dillmann

Aging, Culture, and the Framing of Alzheimer Disease

158

(23)

Martha Holstein

Narrative Practice and the Inner Worlds of the Alzheimer Disease Experience

181

(24)

Jaber F. Gubrium

PART IV Politics, Policy, and the Perspectives of the Caregiver and Patient

205

(64)

The Role of the Concept of Alzheimer Disease in the Development of the Alzheimer's Association in the United States

209

(25)

Patrick J. Fox

The History of the Alzheimer's Association: Future Public Policy Implications

234

(11)

Katherine L. Bick

The Concept of Alzheimer Disease in a Hypercognitive Society

245

(12)

Stephen G. Post

PART V Progress and Its Problems

The Future of Alzheimer Disease

257

(4)

Alzheimer Disease and the New Biology

261

(8)

Larry Altstiel

Steven Paul

The Genetics of Alzheimer Disease: Some Future Implications

269

(38)

Robert Mullan Cook-Deegan

History and the Future of Alzheimer Disease

291

(16)

Peter J. Whitehouse

Index

307

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Concepts of Alzheimer Disease: Biological, Clinical, and Cultural Perspectives

Summary

Author Biography

Table of Contents

Supplemental Materials

FREE SHIPPING

Rent More, Save More! Use code: BBRENTAL

5% off 1 book, 7% off 2 books, 10% off 3+ books

Concepts of Alzheimer Disease: Biological, Clinical, and Cultural Perspectives

Summary

Author Biography

Table of Contents

Supplemental Materials

Digital License