Current Topics in Developmental Biology

In keeping with the tradition of excellence of past volumes of the Current Topics in Developmental Biology series, this volume provides a comprehensive survey of major issues at the forefront of modern developmental biology and regenerative medicine. Astonishing discoveries are presented in thoughtful and forward-looking articles.

Contributors

ix

Preface

xi

1 The Balbiani Body and Germ Cell Determinants: 150 Years Later

Malgorzata Kloc, Szczepan Bilinski, and Laurence D. Etkin

I. Introduction

1

(3)

II. Xenopus

4

(8)

III. Drosophila melanogaster and Other Insects

12

(5)

IV. Caenorhabditis elegans

17

(1)

V. Planarians

18

(1)

VI. Chaetognaths

19

(1)

VII. Ascidians

20

(1)

VIII. Urodeles

21

(1)

IX. Zebrafish and Other Teleosts

21

(3)

X. Birds

24

(1)

XI. Mouse and Other Mammals

24

(1)

XII. Similarities among Different Organisms

25

(4)

Acknowledgments

29

(1)

References

29

(8)

2 Fetal-Maternal Interactions: Prenatal Psychobiological Precursors to Adaptive Infant Development

Matthew F.S.X. Novak

I. Introduction

37

(2)

II. Early Experience and Postnatal Environments

39

(2)

III. Early Experience and Genetics

41

(2)

IV. Early Experience and Learning

43

(1)

V. Complexity Dissonance Theory of Early Experience and Development

44

(1)

VI. The Effects of Prenatal Experience: Establishing the Pacer Range

45

(8)

VII. Conclusion

53

(2)

References

55

(6)

3 Paradoxical Role of Methyl-CpG-Binding Protein 2 in Rett Syndrome

Janine M. LaSalle

I. Introduction to Rett Syndrome

61

(2)

II. CpG Methylation and the Role of McCP2 in Chromatin Organization

63

(2)

III. The Paradoxes

65

(12)

IV. A Reexamination of the Role of McCP2 in the Pathogenesis of Rett Syndrome

77

(4)

Acknowledgments

81

(1)

References

81

(6)

4 Genetic Approaches to Analyzing Mitochondrial Outer Membrane Permeability

Brett H. Graham and William J. Craigen

I. Introduction

87

(2)

II. VDAC and Saccharomyces cerevisiae

89

(1)

III. VDAC and Drosophila melanogaster

90

(3)

IV. VDAC and Mus musculus

93

(19)

V. Conclusions

112

(1)

References

113

(6)

5 Mitochondrial Dynamics in Mammals

Hsiuchen Chen and David C. Chan

I. Introduction

119

(1)

II. The Central Molecular Players

120

(9)

III. Mitochondrial Dynamics in the Control of Mammalian Mitochondrial Morphology

129

(1)

IV. Mitochondrial Dynamics and Mitochondrial Function

130

(3)

V. Mitochondrial Dynamics and Human Disease

133

(1)

VI. Mitochondrial Dynamics in Vertebrate Development

134

(2)

VII. Mitochondrial Dynamics and Apoptosis

136

(2)

VIII. Perspectives and Future Challenges

138

(1)

References

139

(6)

6 Histone Modifications in Corepressor Functions

Judith K. Davie and Sharon Y.R. Dent

I. Introduction

145

(1)

II. Histone Modifications and Regulatory Potential

146

(3)

III. Corepressors and Histone-Modifying Activities

149

(4)

IV. Tupl-Ssn6 Corepressor Complex: A Model for Corepressor Flexibility?

153

(4)

V. Summary and Future Questions

157

(1)

Acknowledgments

158

(1)

References

158

(7)

7 Death by Abi: A Matter of Location

Jiangyu Zhu and Jean Y.J. Wang

I. Introduction

165

(3)

II. Nucleocytoplasmic Shuttling of Abi

168

(5)

III. Cytoplasmic Function of Abl

173

(2)

IV. Nuclear Function of Abl

175

(8)

V. Nuclear Exclusion of BCR-ABL or Abl in Cancer Cells

183

(3)

VI. Conclusions and Future Prospects

186

(1)

References

187

(6)

Index

193

(8)

Contents of Previous Volumes

201

What is included with this book?

The New copy of this book will include any supplemental materials advertised. Please check the title of the book to determine if it should include any access cards, study guides, lab manuals, CDs, etc.

The Used, Rental and eBook copies of this book are not guaranteed to include any supplemental materials. Typically, only the book itself is included. This is true even if the title states it includes any access cards, study guides, lab manuals, CDs, etc.

FREE SHIPPING

Rent More, Save More! Use code: BBRENTAL

5% off 1 book, 7% off 2 books, 10% off 3+ books

Current Topics in Developmental Biology

Summary

Table of Contents

Supplemental Materials

FREE SHIPPING

Rent More, Save More! Use code: BBRENTAL

5% off 1 book, 7% off 2 books, 10% off 3+ books

Current Topics in Developmental Biology

Summary

Table of Contents

Supplemental Materials

Digital License