Destruction of Hazardous Chemicals in the

The book describes practical procedures for the destruction of hazardous chemicals and biological agents in the laboratory in which they are used. The book is a continuation and expansion of "Destruction of Hazardous Chemicals in the Laboratory." It follows the same general approach as the first and second editions but includes a number of new chapters including one on using advanced oxidation techniques as a general means of degrading chemicals. All the monographs from the second edition are incorporated in this volume and are revised and extended as necessary. A number of new monographs describing procedures for the destruction of hazardous chemicals have also been added.The destruction of many pharmaceuticals is also described in this book. This subject has become of increasing importance with recent reports of the detection of pharmaceuticals in the water supply. Finally a new addition is the chapter "General Methods for the Destruction of Hazardous Chemicals in the Laboratory." This chapter describes recent advanced oxidation methods that should be generally applicable to all organic compounds. The methods use commonly available laboratory equipment and reagents.

George Lunn, PhD, has been working as a review chemist for the FDA's Office of New Drug Quality Assessment since 1996. Previously, he was a senior research scientist in the Environmental Control and Research Program at the NCI-Frederick Cancer Research and Development Center. He has written nine books and over sixty papers and review articles.

Eric B. Sansone, PhD, was the director of the Environmental Control and Research Program at the NCI-Frederick Cancer Research and Development Center until his retirement. He has also worked as a consultant in industrial hygiene and air pollution control for a widely diversified group of industries, law firms, universities, and governmental agencies. He has published many articles on the assessment of risk in cancer research.

Preface	p. xi
Acknowledgments	p. xiii
Introduction	p. 1
Specific Methods for the Destruction of Hazardous Chemicals in the Laboratory	p. 17
Acetonitrile	p. 19
Acid Halides and Anhydrides	p. 23
Anatoxins	p. 29
Alkali and Alkaline Earth Metals	p. 37
Alkali Metal Alkoxides	p. 41
Anatoxin-A	p. 43
Aromatic Amines	p. 47
Arsenic	p. 57
Azides	p. 61
Azo and Azoxy Compounds and Tetrazenes	p. 69
Boron Trifluoride and Inorganic Fluorides	p. 77
Botulinum Toxins	p. 81
Brevetoxins	p. 85
Butyllithium	p. 89
Calcium Carbide	p. 93
Carbamic Acid Esters	p. 95
Carbofuran	p. 99
Chloromethylsilanes and Silicon Tetrachloride	p. 101
N-Chlorosuccinimide and Chloramine-T	p. 103
Chlorosulfonic Acid	p. 105
Chromium(VI)	p. 107
Citrinin	p. 113
Complex Metal Hydrides	p. 121
Cyanides and Cyanogen Bromide	p. 129
Cylindrospermopsin	p. 137
Diisopropyl Fluorophosphate	p. 141
Dimethyl Sulfate and Related Compounds	p. 151
Dyes and Biological Stains	p. 163
Ethidium Bromide	p. 201
Haloethers	p. 211
Halogenated Compounds	p. 217
Halogens	p. 229
Heavy Metals	p. 233
Hexamethylphosphoramide	p. 241
Hydrazines	p. 245
Hypochlorites	p. 257
Mercury	p. 261
2-Methylaziridine	p. 267
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)	p. 271
Microcystins	p. 277
4-Nitrobiphenyl	p. 283
3-Nitrofluoranthene and 3-Aminofluoranthene	p. 287
Nitrogen Tetroxide	p. 291
N-Nitroso Compounds: Nitrosamides	p. 293
N-Nitroso Compounds: Nitrosamines	p. 307
Ochratoxin A	p. 319
Organic Nitriles	p. 327
Osmium Tetroxide	p. 331
Palytoxin	p. 335
Patulin	p. 339
Peracids	p. 347
Perchlorates	p. 349
Peroxides and Hydroperoxides	p. 355
Phenol	p. 359
Phosgene	p. 363
Phosphorus and Phosphorus Pentoxide	p. 367
Picric Acid	p. 371
Polycyclic Aromatic Hydrocarbons	p. 375
Polycyclic Heterocyclic Hydrocarbons	p. 387
Potassium Permanganate	p. 405
ß-Propiolactone	p. 407
Protease Inhibitors	p. 411
Ricin	p. 417
Saxitoxin	p. 421
Selenium Compounds	p. 425
Sodium Amide	p. 427
Sterigmatocystin	p. 429
Sulfonyl Fluoride Enzyme Inhibitors	p. 437
Sulmr-Containing Compounds	p. 443
T-2 Toxin	p. 449
Tetrodotoxin	p. 455
Triacetone Triperoxide	p. 459
Uranyl Compounds	p. 463
Methods for the Destruction of Pharmaceuticals in the Laboratory	p. 467
Pharmaceuticals: General Considerations	p. 469
Potassium Permanganate	p. 549
Sodium Hypochlorite	p. 567
Nickel-Aluminum Alloy Reduction	p. 575
Fenton's Reagent	p. 583
Photo-Fenton Reaction	p. 587
Hydrogen Peroxide	p. 591
Hydrogen Peroxide and Horseradish Peroxidase	p. 593
Ozone	p. 595
Hydroxylamine Degradation of ß-Lactams	p. "603
Miscellaneous Chemical Degradation Procedures	p. 605
Photolytic Degradation Procedures	p. 613
Decontamination of Aqueous Solutions	p. 627
Nonspecdtic Methods for the Destruction of Hazardous Chemicals in the Laboratory	p. 631
Appendixes	p. 655
Procedures for Drying Organic Solvents	p. 657
Safety Considerations with Potassium Permanganate	p. 661
Molecular Formula Index	p. 671
Cas Registry Number Index	p. 681
Cross Index of Pharmaceutical Names	p. 693
Cross-Index of Names for Dyes and Biological Stains	p. 729
Name Index	p. 757
Table of Contents provided by Ingram. All Rights Reserved.

What is included with this book?

The New copy of this book will include any supplemental materials advertised. Please check the title of the book to determine if it should include any access cards, study guides, lab manuals, CDs, etc.

The Used, Rental and eBook copies of this book are not guaranteed to include any supplemental materials. Typically, only the book itself is included. This is true even if the title states it includes any access cards, study guides, lab manuals, CDs, etc.

FREE SHIPPING

Amazon no longer offers textbook rentals. We do!

Destruction of Hazardous Chemicals in the Laboratory

Summary

Author Biography

Table of Contents

Supplemental Materials