Ethics and Evidence-Based Medicine:

The growth of evidence-based medicine has occurred against a backdrop of health care reform, managed care, cost containment, and quality improvement. Clinicians have been urged to adopt the rigors of science while remaining true to their 'clinical judgment'. This incisive book reviews the history and conceptual origins of evidence-based practice and discusses key ethical issues that arise in clinical practice, public health, and health policy. It is essential reading for all physicians, and practitioners in epidemiology and public health.

Kenneth W. Goodman is founder and director of the University of Miami's Bioethics Program and its Pan-American Bioethics Initiative.

Preface

ix

Acknowledgments

xii

Foundations and history of evidence-based practice

1

(22)

The research synthesis revolution

23

(18)

Evidence of evidence, and other conceptual challenges

41

(26)

Human subjects, the Internet, databases, and data mining

67

(24)

Evidence at the bedside

91

(22)

Public health policy, uncertainty, and genetics

113

(16)

Ethics and evidence

129

(12)

References

141

(24)

Index

165

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Ethics and Evidence-Based Medicine: Fallibility and Responsibility in Clinical Science

Summary

Author Biography

Table of Contents

Supplemental Materials