Experimental Toxicology

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Introduction to Experimental Toxicology	p. 1
Effects of Physical Form, Route, and Species	p. 4
Influence of Animal Species, Strain, Age, Hormonal, and Nutritional Status	p. 23
Experimental Design	p. 35
The Biochemical Principles of Toxicology	p. 56
Animal Husbandry	p. 82
Inhalation Toxicology	p. 107
Histopathology in Safety Evaluation	p. 119
The Metabolism and Disposition of Xenobiotics	p. 130
Theory and Practice in Metabolic Studies	p. 181
Immunotoxicology - Conceptual Problems	p. 202
Perspectives - The Evaluation of Reproductive Toxicity and Teratogenicity	p. 214
Genetic Toxicology	p. 243
Molecular Toxicology	p. 313
Testing for Carcinogenicity	p. 334
In Vitro Methods for Teratology Testing	p. 360
Assessing Chemical Injury in the Reproductive System	p. 376
Statistics	p. 405
Risk Assessment of Chemicals	p. 442
Epidemiology	p. 464
Information and Consultancy Services in Toxicology	p. 485
Regulations and Advisory Requirements in Relation to Food	p. 491
The Influence of a Growing Environmental Awareness on Toxicology Laboratory Design	p. 505
Good Laboratory Practice	p. 523
Ethics in Experiments on Animals	p. 542
Index	p. 554
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