The Frontal Cortex Organization, Networks, and Function

An in-depth investigation of the structure, neuronal mechanisms, and computations of the frontal lobe that enable higher-level thought.

Experts from neurobiology, neuroanatomy, evolutionary biology, cognitive neuroscience, computational neuroscience, and clinical science examine how the neuronal structure of the frontal lobes enables unique aspects of higher-level thought. Implications for understanding disrupted function in neurological and psychiatric disorders, as well as societal issues, such as volitional control of behavior and educational practice, are also considered.

Trevor W. Robbins is Professor of Cognitive Neuroscience and Director of Research at the Behavioral and Clinical Neuroscience Institute, University of Cambridge.
Suzanne N. Haber is the Dean’s Professor in the Department of Pharmacology and Physiology, University of Rochester.
Marie Banich is Professor at the Institute of Cognitive Science and the Department of Psychology and Neuroscience, University of Colorado Boulder, and Executive Director of the Intermountain Neuroimaging Consortium.

Preface
List of Contributors
1. Introduction
2. Cross-Species Differences in Anatomy and Function: Prefrontal Cortex Homology
3. Prefrontal Cortical Neuronal Physiology: A Cross-Species Perspective
4. Evolutionary Perspectives: Homologies and Analogies
5. Differentiating Functional Contributions across Prefrontal Cortex
6. Position of the Prefrontal Cortex across Cortical Hierarchy
7. The Nature of the Hierarchical Organization of Lateral Prefrontal Cortex
8. Functional Fractionation and Integration: Physiology, Networks, and Behaviors
9. How the Brain Creates Unity and Diversity of Executive Functions
10. Computational Models of Prefrontal Cortex Function
11. Network Approaches to Understand the Prefrontal Cortex and Executive Functio?
12. Integrative Psychological, Computational, and Mechanistic Approaches to Frontal Lobe Function
13. Neurosurgery for Intractable OCD: A Window into Prefrontal Cortical Function in Humans
14. Cognitive Interventions Targeting Executive Functions: Impact on Prefrontal Circuits?
15. Pharmacological Modulation of Prefrontal Cortex in Affective Disorders: Emerging Therapies
16. Translating Understanding of the Prefrontal Cortex to the Bedside and Beyond