Gastrointestinal Pharmacology and Therapeutics

, by Friedman, Gerald; Jacobson, Eugene D., M.D.; McCallum, Richard W.

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ISBN: 9780397516254 | 0397516258
Cover: Hardcover
Copyright: 1/1/1997

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Mount Sinai School of Medicine, New York City. Text on the pharmacology and therapeutics of digestive disease, with emphasis on the underlying pathophysiology of disorders that respond to pharmacologic intervention. 90 contributors, 86 U.S. DNLM: Digestive System Diseases - drug therapy.

I Fundamentals of Gastrointestinal Pharmacology

Fundamentals of Gastrointestinal Pharmacology

(20)

Thomas F. Burks

II Acid-Related Disorders

Helicobacter pylori-Induced Gastritis, Ulceration, and Neoplasia Epidemiology, Pathophysiology, and Therapeutics

(10)

Peter Malfertheiner

James Freston

Gastroesophageal Reflux Disease

(14)

Peter J. Kahrilis

Gastric and Duodenal Ulcers

(10)

Colin W. Howden

Drug-Induced Ulcerogenesis

(10)

Naurang M. Agrawal

Esam Z. Dajani

Management of Acid Hypersecretion in Patients with Zollinger-Ellison Syndrome

(10)

Paul N. Maton

Stress Ulcer Prophylaxis A Systematic Review and Evidence-Based Recommendations

(4)

Deborah J. Cook

III Motility Disorders

Pathophysiology of Gastrointestinal Motility Disorders

(10)

Richard W. McCallum

Principles of Gut Pharmacology

(8)

Richard W. McCallum

Pharmacotherapy of the Esophageal Motor Disorders

(6)

Ravinder K. Mittal

Therapeutic-Pharmacologic Approach to Delayed Gastric Emptying

103

(10)

Richard W. McCallum

Chronic Intestinal Pseudo-Obstruction

113

(14)

G. Nicholas Verne

Charles A. Sninsky

IV Functional Gastrointestinal Disorders

Pharmacologic Therapy of Irritable Bowel Syndrome

127

(6)

Marvin M. Schuster

Functional Gastrointestinal Disorders Chronic Pain Management

133

(14)

Ivan Barofsky

V Pain Management

Gastrointestinal Pain

147

(6)

Charles B. Stacy

VI Gastrointestinal Water Flux

The Pathophysiology of Diarrhea and Constipation The Role of Intestinal Water and Electrolyte Flux

153

(6)

Eugene B. Chang

Cathartics, Laxatives, and Lavage Solutions

159

(16)

Lawrence R. Schiller

Antidiarrheal Therapy

175

(18)

Richard N. Fedorak

VII Infections of the Gut

Pathophysiology of Gastrointestinal Infections Host Defenses Versus Microbial Virulence Traits

193

(8)

Nathan M. Thielman

Richard L. Guerrant

Diagnosis and Pharmacotherapy of Infections Esophagitis

201

(14)

Jonathan P. Moorman

Pharmacology of Small Bowel Infections Pathogens and Therapeutic Approaches

215

(34)

Richard N. Greenberg

Selin Zeytin

Kenneth J. Kortas

Infections of the Colon

249

(18)

Theodore S. Steiner

Richard L. Guerrant

VIII Acquired Immunodeficiency Syndrome and the Gut

Acquired Immunodeficiency Syndrome and the Gut Pathophysiology

267

(10)

Lee M. Oberman

Donald P. Kotler

Esophageal Disease in Acquired Immunodeficiency Syndrome

277

(10)

Maurizio Bonacini

Loren Laine

The Stomach in Human Immunodeficiency Virus Disease

287

(8)

Gerond Lake-Bakaar

Small Bowel Disease

295

(14)

Ronald Fogel

Tamir Ben-Menachem

Colonic Disease in Acquired Immunodeficiency Syndrome

309

(18)

Michael A. Poles

Douglas T. Dieterich

Edward A. Lew

IX Acute and Chronic Noninfections Inflammatory States

Agents Commonly Used in the Treatment of Inflammatory Bowel Disease

327

(22)

James H. Reichheld

Mark A. Peppercorn

New Therapeutic Agents

349

(18)

Miguel D. Regueiro

Mark A. Peppercorn

Medical Management of Ulcerative Colitis and Other Colitis Syndromes

367

(8)

Alain Bitton

Mark A. Peppercorn

Medical Management of Crohn's Disease

375

(8)

Alain Bitton

Mark A. Peppercorn

X Pharmacologic Therapy of Hepatic Disorders

Hepatitis and

383

(18)

Gary L. Davis

Pathophysiology and Pharmacology of Cholestasis

401

(16)

Mitchell L. Schiffman

Douglas M. Heuman

Treatment of Chronic Cholestatic Liver Disease

417

(32)

George Dickstein

Marshall M. Kaplan

Pharmacology and Medical Management of Hepatic Cirrhosis and Fibrosis

449

(16)

Bahri M. Bilir

Nuray Bilir

Alcoholic Liver Disease

465

(24)

Charles S. Lieber

XI Biliary Pharmacology

Primary Sclerosing Cholangitis Pathogenesis and Therapy

489

(12)

Lee McHenry, Jr.

Amy Foxx-Orenstein

Mitchell L. Schiffman

Sphincter of Oddi Current Approaches

501

(12)

Wahid Y. Wassef

Alvin M. Zfass

Prevention and Medical Treatment of Gallstones

513

(14)

Douglas M. Heuman

Mitchell L. Schiffman

Identification and Management of the Hyperlipidemic Patient

527

(14)

R. T. Stravitz

W. M. Pandak

XII Pancreas

Pathophysiology of Acute Pancreatitis

541

(8)

Michael L. Steer

Inflammatory Mediators in Acute Pancreatitis

549

(10)

Heinrich Rinderknecht

Treatment of Acute Pancreatitis From Animal Models to Randomized Human Trials

559

(6)

Scott Tenner

Peter A. Banks

Pathophysiology of Chronic Pancreatitis

565

(6)

Subhash C. Gumber

Steven D. Freedman

Chronic Pancreatitis Pathophysiology and Treatment of Steatorrhea

571

(8)

Daisuke Koike

Eugene P. DiMagno

Chronic Pancreatitis Pathophysiology and Treatment of Pain

579

(6)

Amy Kusske

Howard A. Reber

XIII Pharmacology of Gastrointestinal Vasculature

The Pharmacology of Vasoconstriction

585

(12)

Eugene D. Jacobson

The Medical Therapy of Intestinal Ischemia

597

(6)

Joel S. Levine

XIV Special Issues

Nausea and Vomiting

603

(8)

Richard W. McCallum

Use of Gastrointestinal and Hepatic Drugs During Pregnancy and Lactation

611

(22)

Rajeev Nayar

James H. Lewis

Gastrointestinal Cancer

633

(10)

Lynn H. Ratner

Steven Gruenstein

Pediatric Concerns

643

(12)

Keith J. Benkov

Considerations in the Geriatric Patient

655

(14)

Lidia Pousada

Lawrence J. Brandt

Genetics and Gene Therapy for Gastrointestinal Diseases

669

(8)

Jayanta Roy Chowdhury

Namita Roy Chowdhury

George Y. Wu

XV Drug Assessment

The Drug Development Process An FDA Perspective

677

(16)

Robert Temple

Role of the Pharmaceutical Industry in Drug Development

693

(14)

Robert H. Palmer

Leanne C. Wagner

The Clinical Trials Process

707

(16)

Thomas Q. Garvey III

Larry R. Muenz

Development of Gastrointestinal Drugs for Over-the-Counter Indications

723

(20)

Mark A. Sirgo

Bernard Schachtel

The Economics of Drug Therapy

743

(16)

Ralph O Bischof

David B. Nash

James H. Lewis

Index

759

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Gastrointestinal Pharmacology and Therapeutics

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