Genes, Brain and Development: The

Genetic syndromes and neurodevelopmental disorders that have a genetic basis are associated with cognitive and academic disabilities. Genes, Brain and Development reviews the connections between genes, brain, and behavior for a range of genetic disorders, and also considers lifespan and treatment issues. The content further explores what is known about development in neurogenetic disorders, particularly in the domains of language and mathematics, and shows how this knowledge is pertinent to understanding both these specific disorders, and disorders of language and math more generally. This will be essential reading for a wide range of brain scientists and developmental clinicians, including neuropsychologists, cognitive psychologists, neurologists, psychiatrists, pediatricians, neuroscientists and geneticists.

Marcia A Barnes is Professor Department of Pediatrics, University of Texas Health Science Center at Houston.

List of Contributors	p. ix
Preface	p. xi
Acknowledgments	p. xvi
Connecting genes, brain, and behavior in neurodevelopmental disorders	p. 1
Intergenerational effects of mutations in the fragile X mental retardation 1 gene. Fragile X: A model of X-linked mental retardation and neurodegeneration	p. 3
Autism: Genes, anatomy, and behavioral outcome	p. 19
Development in spina bifida: Neurobiological and environmental factors	p. 53
Genetic disorders and models of neurocognitive development	p. 83
Language and communication in autism spectrum disorders	p. 85
Language development in children with Williams syndrome: New insights from cross-linguistic research	p. 105
Language in Down syndrome: A life-span perspective	p. 122
Genetic disorders as models of mathematics learning disability; Fragile X and Turner syndromes	p. 143
A developmental approach to genetic disorders	p. 175
The use of strategies in embedded figures: Tasks by boys with and without organic mild mental retardation: A review and some experimental evidence	p. 199
Index	p. 216
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Genes, Brain and Development: The Neurocognition of Genetic Disorders

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