Genome Informatics 2009

This volume contains 17 peer-reviewed papers based on the presentations at the 9th Annual International Workshop on Bioinformatics and Systems Biology (IBSB 2009) held at the Life Science Engineering Building of Boston University from July 27 to 29, 2009. This workshop started in 2001 as a platform for doctoral students and young researchers to present and discuss their research results and approaches in bioinformatics and systems biology. It is part of a collaborative educational program involving leading institutions and leaders committed to the following institutions and programs: • Boston University Graduate Program in Bioinformatics • Charité – Universitätsmedizin Berlin • Freie Universität Berlin • Global COE Program — Center of Education and Research for Advanced Genome-Based Medicine, University of Tokyo • The International Research Training Group (IRTG) Genomics and Systems Biology of Molecular Networks • International Research and Training Program on Bioinformatics and Systems Biology, Kyoto University Bioinformatics Center • Max-Delbrück Center for Molecular Medicine in Berlin • Max Planck Institute for Molecular Genetics in Berlin• Max Planck Institute of Molecular Plant Physiology in Potsdam

Preface	p. vii
Scientific Committee	p. ix
Structural Features and Evolution of Protein-Protein Interactions	p. 1
Graphical Analysis and Experimental Evaluation of Saccharomyces cerevisiae P_{TRK_{1 2}} and P_{BMH_{1 2}} Promoter Region	p. 11
Strategies of Non-Sequential Protein Structure Alignments	p. 21
Active Pathway Identification and Classification with Probabilistic Ensembles	p. 30
The Importance of Compartmentalization in Metabolic Flux Models: Yeast as an Ecosystem of Organelles	p. 41
A State Space Representation of VAR Models with Sparse Learning for Dynamic Gene Networks	p. 56
Formal Representation of the High Osmolarity Glycerol Pathway in Yeast	p. 69
Prediction of Regulatory Transcription Factors in T Helper Cell Differentiation and Maintenance	p. 84
Annotating Gene Functions with Integrative Spectral Clustering on Microarray Expressions and Sequences	p. 95
A Novel Meta-Analysis Approach of Cancer Transcriptomes Reveals Prevailing Transcriptional Networks in Cancer Cells	p. 121
New Kernel Methods for Phenotype Prediction from Genotype Data	p. 132
Efficient and Detailed Model of the Local Ca²⁺ Release Unit in the Ventricular Cardiac Myocyte	p. 142
Co-Evolution of Metabolism and Protein Sequences	p. 156
Characterization and Classification of Adverse Drug Interactions	p. 167
Analysis and Prediction of Nutritional Requirements Using Structural Properties of Metabolic Networks and Support Vector Machines	p. 176
Analysis of a Lipid Biosynthesis Protein Family and Phospholipid Structural Variations	p. 191
CaMPDB: A Resource for Calpain and Modulatory Proteolysis	p. 202
Author Index	p. 215
Table of Contents provided by Ingram. All Rights Reserved.

What is included with this book?

The New copy of this book will include any supplemental materials advertised. Please check the title of the book to determine if it should include any access cards, study guides, lab manuals, CDs, etc.

The Used, Rental and eBook copies of this book are not guaranteed to include any supplemental materials. Typically, only the book itself is included. This is true even if the title states it includes any access cards, study guides, lab manuals, CDs, etc.

FREE SHIPPING

Amazon no longer offers textbook rentals. We do!

Genome Informatics 2009

Summary

Table of Contents

Supplemental Materials