Go/No-Go A Journey Into the Research and Treatment of Mental Health Disorders

During a period of creative and emotional crisis in 2022, Apostolides stumbled on a scientific article that would profoundly change her understanding of the human mind. Ten months later, she was interviewing the article’ s lead author and embarking on a journey to unravel current approaches to mental health. Go/No-Go documents her quest to decipher research underlying new treatments for mental disorders— and to understand how it is reshaping our fundamental sense of ourselves. She talks with leading neuroscientists, gathering info about studies, methods, and the resulting treatments that are in the pipeline, soon to be offered to people. All the while, she reflects on her own experiences, making the science more understandable and relevant. With writing that’ s propulsive yet tethered to hard data, she prompts us to look at how contemporary neuroscience is redefining who we are and why we struggle. Through vital questions, readers come to see the flaws and failures of the current approach to mental health— while also learning how society can change course to better support people in their own journey. Go/No-Go is a groundbreaking addition to an urgent dialogue about mental health.

MARIANNE APOSTOLIDES is an award-winning author of eight books, which have been translated and published in over a dozen countries. Her books include I Can't Get You Out of My Mind (finalist for the Foreword INDIES Award in Science Fiction), Sophrosyne, Voluptuous Pleasure (listed among the Globe and Mail's Top 100 Books of 2012), and Swim. She is a two-time recipient of the Chalmers Arts Fellowship and winner of the K.M. Hunter Award for Literature. Apostolides grew up in suburban New York and lives in Toronto, Canada.