Human Molecular Genetics

Now in its third edition, Human Molecular Genetics continues to provide authoritative guidance on the principles underlying human molecular genetics. The content and organization has been fully revised.

Abbreviations
Preface to the first edition
Preface to the second edition
Before we start - genetic data and the Internet
DNA structure and gene expression	p. 1
Chromosomes in cells	p. 27
Genes in pedigrees	p. 55
Cell-based DNA cloning	p. 71
Nucleic acid hybridization assays	p. 95
PCR, DNA sequencing and in vitro mutagenesis	p. 119
Organization of the human genome	p. 139
Human gene expression	p. 169
Instability of the human genome: mutation and DNA repair	p. 209
Physical and transcript mapping	p. 241
Genetic mapping of mendelian characters	p. 269
Genetic mapping of complex characters	p. 283
Genome projects	p. 295
Our place in the tree of life	p. 315
Identifying human disease genes	p. 351
Molecular pathology	p. 377
Genetic testing in individuals and populations	p. 401
Cancer genetics	p. 427
Complex diseases: theory and results	p. 445
Studying human gene structure, expression and function using cultured cells and cell extracts	p. 465
Genetic manipulation of animals	p. 491
Gene therapy and other molecular genetic-based therapeutic approaches	p. 515
Glossary	p. 545
Indexes	p. 557
Table of Contents provided by Blackwell. All Rights Reserved.

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Human Molecular Genetics

Summary

Table of Contents

Supplemental Materials