Immunologic Renal Diseases

, by Neilson, Eric G., M.D.; Couser, William G., M.D.

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ISBN: 9780397516711 | 0397516711
Cover: Hardcover
Copyright: 6/1/1997

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Supplemental Materials

Contributors

(8)

Preface

xix

1. Introduction The History of Renal Immunopathology

(14)

Richard J. Glassock

I. Normal Pathophysiology

(84)

2. Microanatomy of the Kidney: Vessels, Interstitium, and Glomerulus

(28)

Marlies Elger

Brigitte Kaissling

Michel Le Hir

Wilhelm Kriz

3. Glomerular Filtration

(22)

Valentina Kon

Iekuni Ichikawa

4. Normal Immune Responses

(34)

Laurence A. Turka

II. The Immune Response in Renal Injury

(260)

A. Induction of the Nephritogenic Immune Response

(138)

5. Immunogenetics of Renal Disease

(28)

Andrew J. Rees

6. Immunologic Tolerance and the Induction of Autoimmunity

127

(32)

Peter S. Heeger

Eric G. Neilson

7. Renal Expression of MHC Antigens

159

(34)

Philip F. Halloran

8. Antigen Presentation by Renal Parenchyma

193

(10)

Rudolf P. Wuthrich

Gary G. Singer

Vicki Rubin Kelley

9. Membrane Protein Antigens and Other Molecules on Glomerular Cells

203

(14)

Dontscho Kerjaschki

10. Nephritogenic Antigens in the Glomerular Basement Membrane

217

(20)

Dale R. Abrahamson

Gregory B. Vanden Heuvel

William L. Clapp

B. Mechanisms of Immune Injury

237

(122)

11. Pathophysiology of Acute Immune Injury

237

(14)

Roland C. Blantz

Curtis B. Wilson

Francis B. Gabbai

12. Development and Expression of Nephritogenic T Cells

251

(14)

Carolyn J. kelly

13. Molecular Structure and Expression of Nephritogenic Autoantibodies

265

(26)

Mary H. Foster

Michael P. Madaio

14. Mechanisms of Immune Complex Formation and Deposition in Renal Structures

291

(18)

Christine K. Abrass

15. Apoptosis in Acute Renal Inflammation

309

(22)

John S. Savill

Andrew F. Mooney

Jeremy Hughes

16. Mechanisms of Allograft Rejection

331

(28)

James M. Pattison

Richard K. Sibley

Alan M. Krensky

III. Mediation of Immune Renal Injury

359

(236)

A. Humoral Mediators of Immune Injury

359

(140)

17. Glomerular Injury Due to Antibody Alone

359

(18)

David J. Salant

Yasuhiro Natori

Fujio Shimizu

18. Complement and Complement Regulatory Proteins in Renal Disease

377

(20)

Lee A. Hebert

Fernando G. Cosio

Daniel J. Birmingham

19. Proteases and Oxidants in Glomerular Injury

397

(20)

Gur P. Kaushal

Sudhir V. Shah

20. Growth Factors and Cytokines

417

(38)

Jurjen Floege

Andrew J. Rees

21. Endothelin and Nitric Oxide

455

(14)

Tobias A. Marsen

Michael J. Dunn

22. Prostaglandins and Leukotrienes

469

(20)

Rolf A. K. Stahl

23. Coagulation and Thrombosis in Immunilogic Renal Diseases

489

(10)

Carla Zoja

Giuseppe Remuzzi

B. Cellular Mediators of Immune Injury

499

(96)

24. The Role of Chemoattractants in Renal Disease

499

(20)

Theodore M. Danoff

Eric G. Neilson

25. Leukocyte Adhesion

519

(28)

Marie-Josee Hebert

Hugh R. Brady

26. Neutrophils

547

(14)

Richard J. Johnson

Seymour J. Klebanoff

William G. Couser

27. Platelets

561

(14)

Jeffrey L. Barnes

28. Macrophages in Immune Renal Injury

575

(20)

David J. Nikolic-Paterson

Hui Y. Lan

Robert C. Atkins

IV. Response in Immune Injury

595

(134)

29. Glomerular Mesangial Cells

595

(32)

R. Bernd Sterzel

Harald D. Rupprecht

30. Endothelial Responses to Immunne Injury

627

(28)

Barbara J. Ballermann

31. Glomerular Epithelial Cells

655

(14)

Stephen Adler

32. Glomerular Inflammation and Crescent Formation

669

(14)

Roger C. Wiggins

Lawrence B. Holzman

Daniel J. Legault

33. Pathophysiology of Progressive Renal Disease

683

(22)

Agnes B. Fogo

Valentina Kon

34. Renal Fibrogenesis and Progression

705

(24)

Frank Strutz

Gerhard A. Muller

V. Animal Models of Immunologic Renal Diseases

729

(76)

35. Immune Models of Glomerular Injury

729

(46)

Curtis B. Wilson

36. Immune Models of Tubulointerstitial Injury

775

(30)

Curtis B. Wilson

VI. Clinical Aspects of Immunologic Renal Diseases

805

(430)

A. Patient Evaluation and General Considerations

805

(110)

37. Clinical Evaluation and Management of Hematuria and Proteinuria

805

(32)

Karl G. Koenig

W. Kline Bolton

38. Morphologic Evaluation of Immune Renal Disease

837

(24)

Michael Kashgarian

39. Mechanisms and Risks of Immunosuppresive Therapy

861

(26)

Angelo M. de Mattos

Ali J. Olyaei

William M. Bennett

40. Interpretation of Clinical Studies of Renal Disease

887

(28)

Tom Greene

Joseph Lau

Andrew S. Levey

B. Primary Glomerular Diseases

915

(140)

41. Postinfectious Glomerulonephritis

915

(30)

William G. Couser

Richard J. Johnson

42. Immunoglobulin A Nephropathy

945

(14)

Leendert A. Van Es

43. Anti-Glomerular Basement Membrane Disease

959

(16)

Catherine M. Meyers

Raghuram Kalluri

Eric G. Neilson

44. Minimal-Change Nephrotic Syndrome

975

(18)

Kevin E.C. Meyers

Dean A. Kujubu

Bernard S. Kaplan

45. Mesangioproliferative Disease

993

(10)

Hai Yan Wang

Yi Pu Chen

46. Focal Segmental Glomerulosclerosis

1003

(24)

H. William Schnaper

47. Membranous Nephropathy

1027

(28)

William G. Couser

Charles E. Alpers

C. Secondary Glomerular Diseases

1055

(166)

48. Systemic Lupus Erythematosus

1055

(44)

J. Stewart Cameron

49. Renal Vasculitis

1099

(20)

Ronald J. Falk

J. Charles Jennette

50. Henoch-Schonlein Purpura

1119

(14)

Norishige Yoshikawa

51. Idiopathic Membranoproliferative Glomerulonephritis

1133

(14)

Robert B. Miller

Clifford E. Kashtan

Barbara A. Burke

Youngki Kim

52. Amyloidosis and the Dysproteinemias

1147

(14)

Melvin M. Schwartz

Stephen M. Korbet

53. Hemolytic Uremic Syndrome and Thrombotic Thrombocytopenic Purpura

1161

(20)

John R. Brandt

Ellis D. Avner

54. Clinical and Immunopathogenic Aspects of Human Immunodeficiency Virus-Associated Renal Diseases

1181

(18)

Pual L. Kimmel

55. Recurrent and De Novo Glomerular Disease in Renal Transplants

1199

(22)

J. Andrew Bertolatus

Lawrence G. Hunsicker

D. Interstitial Nephritis

1221

(14)

56. Acute Interstitial Nephritis

1221

(14)

Gerald B. Appel

Index

1235

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