Indwelling Neural Implants: Strategies for Contending with the In Vivo Environment

A compendium of contributions from noted experts in neuroprosthetics and tissue repair, this book addresses the impact, characterization, and mitigation of the healing of tissues that surround an implant. It describes the differences among wound healing in the CNS, PNS, subcutaneous tissue, and bone and examines performance issues of implanted neuroprosthetics arising from the chemical, mechanical, thermal, and electrical impact on surrounding tissue. Contributions present both in vitro and in vivoapproaches to assessing wound healing response to materials and describe molecular and materials strategies for intervening in CNS wound repair and enhancing the electrical communication between electrode and surrounding tissue.