Innate Immune System of Skin and Oral Mucosa

Topically applied products and medications can profoundly affect skins barrier function and overall health. Bursting with suggestions to assist research and development, Innate Immune System of Skin and Oral Mucosa: Properties and Impact in Pharmaceutics, Cosmetics, and Personal Care Products provides a comprehensive overview on the innate immune system and its relevance to pharmaceutics, cosmetic chemistry, and personal care products. The book allows pharmaceutical and medical professionals to assess accumulated knowledge and develop an understanding that will pave the way for next generation treatment avenues, preventative approaches, and drug development.

Nava Dayan PhD, is the R&D Director at Lipo Chemicals Inc. and an Associate Adjunct Professor in the Ernest Mario School of Pharmacy at Rutgers University. During her twenty four years of experience she has specialized in a variety of areas related to skin treatment, especially in the research and understanding of the interaction between topically applied compounds and the skin. Dr. Dayan has received numerous awards for excellence for various papers she has authored. She is the author and coauthor of more than a hundred and fifty publications, including book chapters, and has been granted eight patents. She is also the editor of three books, including Formulating, Packaging, and Marketing of Natural Cosmetic Products (Wiley).

Philip W. Wertz PhD, is a Professor in the Department of Oral Pathology, Radiology, and Medicine at the University of Iowa College of Dentistry and in The Dows Institute for Dental Research. He is currently on the Editorial Advisory Board of the International Journal of Cosmetic Science and the Editorial Board of the TransDermal and Journal of Lipids.

Preface	p. ix
Contributors	p. xi
Overview of Skin and Mucosal Innate Immunity: History, Ethics, and Science
Germ free: Hygiene History and Consuming Antimicrobial and Antiseptic products	p. 3
Ethical Responsibilities in Formulating, Marketing, and using Antimicrobial personal products	p. 43
Role of Stratum Corneum in Permeability barrier function and Antimicrobial defense	p. 59
Antimicrobial Lipids and Peptides
Antimicrobial Lipids of the Skin and Oral Mucosa	p. 75
Resident Microflora and Antimicrobial Peptides of Skin	p. 83
Defensins	p. 109
Antimicrobial Peptides of Skin and Oral Mucosa	p. 117
Vernix Caseosa and Immate Immunity	p. 145
Host Cellular Components of Innate Immunity
Sentinel role of Mast cells in Innate Immunity	p. 173
Cellular Immunity of the Skin: Langerhans cells and Dendritic cells	p. 195
Innate Immunity response to stress and Aging
Changes in Skin Immunity with age and Disease	p. 217
Epidermis as a shield from Radiation and Oxidative Stress	p. 259
The Impaction the Skin's Innate Immunity by Cosmetic products applied to the skin and scalp	p. 275
UV-induced Immunosuppression of skin	p. 281
Innate Immunity Microbial challenges
Deranged Antimicrobial barrier in Atopic Dermatitis: roles of Sphingosine, Hexadecenoic acid, and beta-defensine-2	p. 307
Resident Microflora of the skin and oral Mucosa	p. 352
Corynebacterium species and their role in the generation of Human Malodor	p. 333
Index	p. 351
Table of Contents provided by Ingram. All Rights Reserved.

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Innate Immune System of Skin and Oral Mucosa Properties and Impact in Pharmaceutics, Cosmetics, and Personal Care Products

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