Interventional Cardiology Principles and Practice

• Contains a radically expanded chapter contents list presented in four clear sections; coronary interventions, interventional pharmacology, structural heart interventions, and endovascular therapy
• Includes 46 new chapters, including the latest advances in bioresorbable coronary stents, advanced transcatheter aortic valve replacement, MitraClip, new transcatheter mitral valve interventions, and more 
• Chapters are templated for rapid referral, beginning with pathophysiological background and relevant pathology, moving to mechanisms of treatment, device description, procedural techniques, follow-up care, and ending with risks, contraindications and complications
• Multiple choice questions at the end of each chapter for self-assessment, a total of more than 400 MCQs in the book 
• Features 19 procedural videos, hosted on a companion website

GEORGE D. DANGAS, MD, PhD, Professor of Medicine, Mount Sinai School of Medicine, Mount Sinai Hospital, New York, USA and Center for Interventional Vascular Therapy, Division of Cardiology, Columbia University Medical Center, New York, USA

CARLO DI MARIO, MD, PhD, Professor of Cardiology, National Heart and Lung Institute, Imperial College, London and Consultant Cardiologist, Department of Invasive Cardiology, Royal Brompton Hospital, London, UK

Nicholas Kipshidze, MD, PHD, Director, Endoluminal and Molecular Interventions, Lenox Hill Heart and Vascular Institute, New York, USA

About the Companion Website   vi

Contributors   vii

Foreword   xvi Preface   xvii

Acknowledgments   xviii

Part I Principles and Techniques   1

Section I Basic Knowledge  3

1 Atherogenesis and Inflammation    3
Umair Hayat, Vikas Thondapu, Tim Tsay, and Peter Barlis

2 The Essentials of Femoral Vascular Access and Closure   17
Ted Feldman and Mohammad Sarraf

3 Radial Artery, Alternative Arm Access, and Related Techniques   27
Thomas J. Ford, Martin K.C. Ng, Vikas Thondapu, and Peter Barlis

4 Optimal Angiographic Views for Coronary Angioplasty   34
Gioel Gabrio Secco and Carlo Di Mario

5 Material Selection   44
Sahil A. Parikh, Michele Pighi, and Carlo Di Mario

Section II  Imaging and Physiology    59

6 Physiologic Assessment in the Cardiac Catheterization Laboratory: CFR, FFR, iFR, and Beyond   59
Sukhjinder Nijjer and Justin Davies

7 Intravascular Ultrasound and Virtual Histology: Principles, Image Interpretation, and Clinical Applications    71
Adriano Caixeta, Akiko Maehara, and Gary S. Mintz

8 Optical Coherence Tomography, Near�-Infrared Spectroscopy, and Near�-Infrared Fluorescence Molecular Imaging    91
Ismail Dogu Kilic, Roberta Serdoz, Enrico Fabris, Farouc Amin Jaffer, and Carlo Di Mario

9 Complementary Imaging Techniques: Multislice Computed Tomography of Coronary Arteries    107
Omosalewa O. Lalude, Francesca Pugliese, Pim J. de Feyter, and Stamatios Lerakis

10 Cardiovascular Magnetic Resonance Imaging   126
Omosalewa O. Lalude and Stamatios Lerakis

Section III PCI in Different Clinical Settings  138

11 Stable Coronary Artery Disease   138
Abhiram Prasad and Bernard J. Gersh

12 PCI Strategies in Acute Coronary Syndromes without ST Segment Elevation (NSTEACS)   148
Georgios E. Christakopoulos, Subhash Banerjee, and Emmanouil S. Brilakis

13 Primary and Rescue PCI in Acute Myocardial Infarction and Elements of Myocardial Conditioning    155
Tayo Addo, Neil Swanson, and Anthony Gershlick

14 The Management of Cardiogenic Shock and Hemodynamic Support Devices and Techniques   163
Bimmer E.P.M. Claessen, Dagmar Ouweneel, and José P.S. Henriques

Section IV PCI in Different Lesion Types   168

15 Percutaneous Coronary Intervention in Unprotected Left Main  168
Gill Louise Buchanan, Alaide Chieffo, and Antonio Colombo

16 Bifurcation Lesion Stenting   175
Yves Louvard, Thierry Lefevre, Bernard Chevalier, and Philippe Garot

17 Risk Stratification Approach to Multivessel Coronary Artery Disease   185
Davide Capodanno and Corrado Tamburino

18 Chronic Total Coronary Occlusion    190
Gerald S. Werner and Emmanouil S. Brilakis

19 Percutaneous Coronary Intervention of Arterial and Vein Grafts   201
Bimmer E.P.M. Claessen, José P.S. Henriques, and George D. Dangas

20 Interventional Approach in Small Vessel, Diffuse, and Tortuous Coronary Artery Disease    205
Robert Pyo

21 In�-Stent Restenosis in New Generation DES Era   213
Marco G. Mennuni and Patrizia Presbitero

Section V Special Techniques and Complications    224

22 Laser, Rotational, and Orbital Coronary Atherectomy   224
Kaleab N. Asrress, Peter O’Kane, Robert Pyo, and Simon R. Redwood

23 Thrombus�-Containing Lesions    233
Giovanni Luigi De Maria and Adrian P. Banning

24 Specialized Balloons in Percutaneous Coronary Intervention: Cutting, Scoring, Gliding, and Drug�-Eluting Balloons   244
Bimmer E.P.M. Claessen, José P.S. Henriques, and George D. Dangas

25 Coronary Artery Dissections, Perforations, and the No�-Reflow Phenomenon    248
Adriano Caixeta, Luiz Fernando Ybarra, Azeem Latib, Flavio Airoldi, Roxana Mehran, and George D. Dangas

26 Access Site Complications   267
Jose M. Wiley, Fernando Pastor, and Cristina Sanina

27 Renal Insufficiency and the Impact of Contrast Agents    274
Michael Donahue and Carlo Briguori

28 Radiation Management in Interventional Cardiology    282
Stephen Balter and Charles E. Chambers

29 Concepts of Cell Therapy and Myocardial Regeneration    290
Kevin O’Gallagher, Zoë Astroulakis, Alex Sirker, and Jonathan M. Hill

Section VI Clinical Trials in Coronary Heart Disease  296

30 Statistical Essentials in the Design and Analysis of Clinical Trials   296
Usman Baber and Stuart J. Pocock

31 Historical Perspective of Sirolimus and Paclitaxel�-Eluting Stent Clinical Studies   301
Adriano Caixeta, Leonardo Guimarães, Philippe Généreux, and George D. Dangas

32 Cobalt�-Chromium Everolimus�-Eluting Stents    313
Vikas Thondapu, Yoshinobu Onuma, Bimmer E.P.M. Claessen, Patrick W. Serruys, and Peter Barlis

33 Platinum�-Chromium Everolimus�-Eluting Stents    326
Vikas Thondapu, Bimmer E.P.M. Claessen, George D. Dangas, Patrick W. Serruys, and Peter Barlis

34 Bioresorbable Stents   335
Gianluca Caiazzo, Alessio Mattesini, Ciro Indolfi, and Carlo Di Mario

35 The Biolimus Stent Family   344
Anna Franzone, Raffaele Piccolo, and Stephan Windecker

36 The Biotronik Stent Family   360
Anna Franzone, Raffaele Piccolo, and Stephan Windecker

37 Novel Drug�-Eluting Stent Systems   368
J. Ribamar Costa, Jr., Adriano Caixeta, and Alexandre A.C. Abizaid

Part II Interventional Pharmacology   377

Section I Fundamentals of Interventional Pharmacology  379

38 Basics of Antiplatelet and Anticoagulant Therapy for Cardiovascular Disease   379
Piera Capranzano and Dominick J. Angiolillo

39 Balance of Ischemia and Bleeding in Selecting Antithrombotic Regimens    389
Bimmer E.P.M. Claessen and José P.S. Henriques

Section II  Pharmacological Agents    397

40 Oral Antiplatelet Agents in PCI   397
Jonathan A. Batty, Joseph R. Dunford, George D. Dangas, and Vijay Kunadian

41 Parenteral Anticoagulant Agents in PCI    408
Piera Capranzano, Corrado Tamburino, and George D. Dangas

42 Parenteral Antiplatelet Agents in PCI    415
Piera Capranzano, Giuseppe Gargiulo, and Corrado Tamburino

43 Role of Parenteral Agents in PCI for Stable Patients   421
Joanna Ghobrial, David A. Burke, and Duane S. Pinto

44 Vasoactive and Antiarrhythmic Drugs During PCI  432
Bimmer E.P.M. Claessen and José P.S. Henriques

45 The Optimal Duration of Dual Antiplatelet Therapy After PCI   436
Mikkel Malby Schoos, Roxana Mehran, and George D. Dangas

46 Triple Antiplatelet Therapy and Combinations with Oral Anticoagulants After PCI   443
Jonathan A. Batty, Joseph R. Dunford, Roxana Mehran, and Vijay Kunadian

Section III Pharmacological Testing    453

47 Peri�-procedural Platelet Function Testing in Risk Stratification and Clinical Decision Making   453
Paul A. Gurbel, Fang Liu, Gailing Chen, and Udaya S. Tantry

48 Genetics and Pharmacogenetics in Interventional Cardiology   459
Hillary Johnston�-Cox, Johan L.M. Björkegren, and Jason C. Kovacic

49 Monitoring and Reversal of Anticoagulation and Antiplatelet Agents   469
Gregory W. Yost and Steven R. Steinhubl

Part III Hypertension and Structural Heart Disease  485

Section I Systemic and Pulmonary Hypertension  487

50 Right Heart Catheterization and Pulmonary Hemodynamics  487
P. Christian Schulze

51 Treatment of Pulmonary Embolism: Medical, Surgical, and Percutaneous   491
Ian del Conde and Barry T. Katzen

52 Renal Denervation for Resistant Hypertension    499
Hitesh C. Patel, Carl Hayward, Sebastian Ewen, and Felix Mahfoud

Section II Structural Heart Interventions   507

53 Antithrombotic Strategies in Valvular and Structural Heart Disease Interventions  507
Mikkel Malby Schoos, Davide Capodanno, and George D. Dangas

54 Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy    517
Amir�-Ali Fassa, George D. Dangas, and Ulrich Sigwart

55 Left Atrial Appendage Exclusion   525
Jorge G. Panizo and Jacob S. Koruth

56 Cryptogenic Stroke, Patent Foramen Ovale, and ASD Closure   530
Barry Love

57 Paravalvular Leak Closure and Ventricular Septal Defect Closure   540
Saurabh Sanon, Mackram F. Eleid, Allison K. Cabalka, and Charanjit S. Rihal

Section III Valvular Heart Disease Interventions   546

58 Aortic Valvuloplasty and Large�-Bore Percutaneous Arterial Access   546
Matthew I. Tomey, Annapoorna S. Kini, Samin K. Sharma, and Jason C. Kovacic

59 Transfemoral Aortic Valve Implantation: Preparation, Implantation, and Complications    558
Brandon M. Jones, Samir R. Kapadia, Amar Krishnaswamy, Stephanie Mick, and E. Murat Tuzcu

60 Transthoracic Aortic Valve Implantation    569
Giuseppe Bruschi, Kaleab N. Asrress, Paola Colombo, and Vinayak N. Bapat

61 New Aortic Valve Technologies   575
Dimytri Alexandre Siqueira and Alexandre A.C. Abizaid

62 Transseptal Puncture    582
Alec Vahanian, Dominique Himbert, Fabrice Extramiana, Gregory Ducrocq, and Eric Brochet

63 Principles of Carpentier’s Reconstructive Surgery in Degenerative Mitral Valve Disease   592
Farzan Filsoufi and Alain Carpentier

64 Mitral Valve Repair: MitraClip and Emerging Techniques   599
Ted Feldman, Mohammad Sarraf, Mayra Guerrero, and Francesco Maisano

65 Balloon Mitral Valvuloplasty   606
C.N. Manjunath, Nagaraja Moorthy, and Upendra Kaul

66 Pulmonary Artery and Valve Catheter�-Based Interventions    619
Kasey Chaszczewski, Damien Kenny,  and Ziyad M. Hijazi

67 Imaging for Planning and Guidance for Structural Heart Interventions   629
Ankit Parikh and Stamatios Lerakis

Part IV Vascular Disease for the Interventionalist   641

Section I Cerebrovascular Disease   643

68 Acute Stroke Intervention    643
Stefan C. Bertog, Iris Q. Grunwald, Anna Luisa Kühn, Laura Vaskelyte, Ilona Hofmann, Sameer Gafoor, Markus Reinartz, Predrag Matic, and Horst Sievert

69 Carotid Artery Angioplasty and Stenting    653
Alberto Cremonesi, Shane Gieowarsingh, and Fausto Castriota

70 Cerebral Aneurysms: Diagnosis, Indications, and Strategies for Endovascular Treatment    671
Gyula Gál

Section II Aorta and Branch Diseases   677

71 Management of Acute Aortic Syndromes   677
Christoph A. Nienaber and Rachel E. Clough

72 Thoracic Endovascular Aortic Aneurysm Repair   687
Paul S. Lajos and Michael L. Marin

73 Endovascular Aortic Aneurysm Repair   692
William Beckerman, Paul S. Lajos, and Peter L. Faries

74 Acute and Chronic Mesenteric Ischemia    698
Robert J. Rosen, Amit Jain, and Jennifer Drury

75 Renal Artery Interventions    705
Mark Shipeng Yu, Kun Xiang, Steven T. Haller, and Christopher J. Cooper

76 Revascularization for Arteries in the Pelvis   713
Femi Philip and Jason H. Rogers

Section III Peripheral Arterial Disease  721

77 Iliac Interventions    721
Manish Taneja and Apoorva Gogna

78 Superficial Femoral Artery Interventions    726
Cristina Sanina, Pedro R. Cox�-Alomar, Prakash Krishnan, and Jose M. Wiley

79 Popliteal Artery Interventions    733
Karthik Gujja, Gopi Punukollu, Vishal Kapur, and Prakash Krishnan

80 Below the Knee Interventions in Critical Limb Ischemia   738
Karthik Gujja, Katarzyna Nasiadko, Arthur Tarricone, and Prakash Krishnan

81 Subclavian, Vertebral, and Upper Extremity Vascular Disease   748
Ian Del Conde, Cristina Sanina, and Jose M. Wiley

Section IV Venous Disease/Interventions  754

82 Antithrombotic Strategies in Endovascular Interventions: Current Status and Future Directions   754
Mehdi H. Shishehbor

83 Chronic Venous Insufficiency   759
Karthik Gujja, Cristina Sanina, and Jose M. Wiley

84 Cardiac Vein Anatomy and Transcoronary Sinus Catheter Interventions in Myocardial Ischemia  768
Werner Mohl, Levente Molnár, and Béla Merkely

Index   776

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