Leukaemia Diagnosis

UP-TO-DATE PRACTICAL GUIDE TO LEUKAEMIA DIAGNOSIS

Written by a renowned expert this practical guide had been fully revised and updated. The book covers recent advances in the fields of immunophenotyping, cytogenetics and molecular genetics. It illustrates how laboratory techniques are used for the diagnosis and classification of leukaemia and includes images of abnormal cells to aid diagnosis.

This fifth edition:

• Incorporates the recommendations of the 2015 WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues
• Includes 300 high quality full colour digital images of abnormal cells in leukaemia and lymphoma
• Full colour diagrams and helpful tables clarify and summarise key points throughout

Essential reading for every haematologist and haematopathologist. 

Barbara J. Bain, MB BS, FRACP, FRCPath, Professor of Diagnostic Haematology, St Mary's Hospital Campus, Imperial College London Faculty of Medicine, and Honorary Consultant Haematologist, St Mary's Hospital, London, UK

Preface vii

Acknowledgements vii

Commonly Used Abbreviations ix

1 The Nature of Leukaemia, Cytology, Cytochemistry and the Morphological Classification of Acute Leukaemia 1

2 Immunophenotyping and Cytogenetic/Molecular Genetic Analysis 69

3 Acute Myeloid Leukaemia: Integration of Morphological, Immunophenotypic and Genetic Information and the WHO Classification 135

4 Acute Lymphoblastic Leukaemia and Acute Leukaemia of Ambiguous Lineage 249

5 The Myelodysplastic Syndromes and the Myelodysplastic/Myeloproliferative Neoplasms 295

6 Chronic Myeloid Leukaemias 371

7 Lymphoid Leukaemias of Mature B, T and Natural Killer Cells 417

8 Leukaemia Diagnosis in Resource-Poor Countries 525

Index 539

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