Long-Term Potentiation

Controversy is a hallmark of an evolving field. Since its discovery by neuroscientists in 1972, long-term potentiation (LTP) of synaptic transmission has been a prime candidate for a cellular explanation of memory and an exciting source of controversies that run from the molecular to the behavioral level. The twenty-five contributions in this pivotal volume cover the most recent discoveries and debates, providing a comprehensive update on LTP for those who work in the field of learning and memory and a solid introduction to the properties, mechanisms, and functions of LTP for investigators in other areas of brain research. Michel Baudry is Associate Professor in the Department of Biology at the University of Southern California. Joel L. Davis is Program Manager of the Biological Intelligence Section at the Office of Naval Research. Contributors. I. Pre- versus the Post-Synaptic Changes in LTP. T.V.P. Bliss, M.P. Clements, M.L. Errington, M.A. Lynch, and J.H. Williams. L. Aniksztejn, M.P. Roisin, A. Represa, and Y. Ben-Ari. Z.I. Bashir, S.T. Alford, J.F. Blake, B.G. Frenguelli, S.N. Davies, K. G. Reymann and G.L. Collingridge. W.E.J.M. Ghijsen, and F.H. Lopes Da Silva. F. Crepel. J.M. Bekkers and C.F. Stevens. B.L. McNaughton. R. Malinow and R. Tsien. J. Larson, J. Ambros-Ingerson, and G. Lynch. II. The Role of Different CalciumDependent Enzymes in LTP. D.J. Perkel and R.A. Nicoll. A. Routtenberg. M. Baudry. P.N.E. De Graan and W.H. Gispen. III. The Biophysical/Structural Changes in LTP. C. Wallace, N. Hawrylak and W. Greenough. H.J. Matthies. IV. The Relationship between LTP and Learning and Memory.C.A. Barnes, B.L. McNaughton, and C.A. Erickson. C. Mondadori and L. Weiskrantz. R.G.M. Morris, S. Davis, and S.P. Butcher. S. LaRoche, V. Doyere, and C. Redini Del Negro. B. Soumireut-Mourat. V. LTP Rules in Neural Networks. T.W. Berger and M.F. Yeckel. T. Brown, A.M. Zador, and Z.F. Mainen. R. Granger, A. Cobas, and G. Lynch. J.C. Taylor. Y. Fregnac.