The MAK-Collection for Occupational Health and Safety Part I: MAK Value Documentations, Volume 27

This volume provides documentations for the established MAK values (maximum workplace concentrations) of selected occupational toxicants, including an authoritative review of the available toxicological studies and data. For each substance, the toxic effects, mechanisms and modes of action, toxicogenetics and metabolism, effects in man and animals are described. In addition, the carcinogenic, germ-cell mutagenic, sensitizing or skin-resorptive effects as well as their toxicity to the reproductive system are evaluated, plus basic physico-chemical data are provided. The documentations are thus not only essential for the application of MAK values but also provide a concise toxicological overview for each substance.

Andrea Hartwig received her Diploma in Chemistry in 1984, finished in 1987 her PhD thesis and 1996 her Habilitation in Biochemistry at the University of Bremen. In 1998, she became Professor for Food Chemistry in Karlsruhe, Germany. The main research area focuses on the impact of carcinogenic metal compounds as well as essential trace elements on genomic stability, with special emphasis on DNA damage induction and effects on DNA repair, gene expression and cell cycle control.

Polycyclic aromatic hydrocarbons (PAH)
Benzo[a]anthracene
Cyclopenta[cd]pyrene

(tentative contents)