Marijuana and Madness

The second edition of this critically acclaimed and award-winning text provides a comprehensive overview of the psychiatry and neuroscience of Cannabis sativa (marijuana). It outlines the very latest developments in our understanding of the human cannabinoid system, and links this knowledge to clinical and epidemiological facts about the impact of cannabis on mental health. Clinically focused chapters review not only the direct psychomimetic properties of cannabis, but also the impact consumption has on the courses of evolving or established mental illnesses such as schizophrenia. Effects of cannabis on mood are reviewed, as are its effects on cognition. This new edition has been extensively updated and expanded with 10 new chapters to incorporate major new research findings. This book will be of interest to all members of the mental health team, as well as to neuroscientists, epidemiologists, public health specialists and those involved in drug and alcohol research.

Foreword
Preface
Pharmacology of Cannabis and the Endocannabinoid System
The cannabinoid system from the point of view of a chemist
The function of the endocannabinoid system
How cannabis works in the brain
The Changing Face of Cannabis
The epidemiology of cannabis use: an international perspective
Is cannabis becoming more potent? Mahmoud ElSohly
Health policy and cannabis
Cannabis and the Brain
Cannabis, endocannabinoids and neurodevelopment
The impact of pubertal exposure to cannabis on the brain: a focus on animal studies
Cannabis and cognition: short and long-term effects
Does cannabis cause lasting brain damage?
Cannabis, Anxiety and Mood
Acute and subacute psychiatric effects of cannabis
The association between cannabis use and depression
Cannabis and bipolar disorder Carol Silberberg
Cannabis and Psychosis
Cannabis and psychosis proneness
Genetic factors that moderate the psychomimetic effects of cannabis
Cannabis causes positive, negative, cognitive symptoms and produces impairments in electrophysiological indices of information processing
The neural basis for the acute effects of cannabis on learning and psychosis
Cannabinoids and Schizophrenia: Aetiopathology and Treatment Implications
Does cannabis cause schizophrenia?
Postmortem studies of the brain cannabinoid system in schizophrenia
The endogenous cannabinoid system in schizophrenia
The endocannabinoid system as a target for pharmacotherapy of schizophrenia
Cannabis and its Impact on Schizophrenia
Acute effects of cannabis in established schizophrenia
Cannabis and the long-term course of schizophrenia
Motives that maintain cannabis use in schizophrenia
Treatment interventions for cannabis abuse in people with psychosis
Integration
Cannabis and mental illness: an integration
Index
Table of Contents provided by Publisher. All Rights Reserved.

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Marijuana and Madness

Summary

Table of Contents

Supplemental Materials