Mechanical Reperfusion for STEMI: From

As a leading cause of death in developed countries, ST-segment elevation myocardial infarction and its various treatment options are of great concern to those in the cardiology field. This text presents evidence-based chapters that supply clinicians with real-life situations and strategies to treat STEMI patients more effectively and at a quicker pace. A highly illustrated and fully referenced source, this comprehensive text provides both a scientific background and a practical overview of the invasive management of STEMI patients.

Giuseppe De Luca, MD, PhD, is Chief of Interventional Cardiology at the Azienda Ospedaliera-Universitaria "Maggiore della Carit" in Novara, Italy. Having performed over 3,000 coronary angioplasties, Dr. De Luca is a major worldwide expert in the setting of acute myocardial infarction. He is a member of the Scientific Committee of the European Association of Percutaneous Coronary Intervention (EAPCI) and the recipient of several prestigious international scientific awards, including the Thomas J. Linnemeier Spirit of Interventional Cardiology Young Investigator Award. An author of over 100 peer-reviewed journal publications, Dr. De Luca is an Assistant Professor of Cardiology at Eastern Piedmont University. He is Director of the University's Laboratory of Molecular Cardiology, where he is currently conducting several studies on pharmacogenomics, genetic predisposition to atherosclerosis, no-reflow phenomenon, and left ventricular remodeling after STEMI. Alexandra J. Lansky, MD, is Director of Clinical Services of the Center for Interventional Vascular Therapy at the New York-Presbyterian Hospital/Columbia University Medical Center. She is an Associate Professor of Clinical Medicine at Columbia University College of Physicians and Surgeons. An author of over 100 peer-reviewed manuscripts and book chapters, Dr. Lansky is the lead author of the American Heart Association Statement on Interventional Cardiology in Women. She is also a founding member of the Cardiovascular Research Foundation (CRF), where she serves as Joint Chief Scientific Officer for the Clinical Trials Center and Director of the Women's Cardiovascular Health Initiative. She has served as the principle investigator on numerous angiographic and intravascular ultrasound laboratory studies and has furthered her research on women's cardiovascular health.

Foreword	p. vii
Preface	p. ix
Contributors	p. xv
Rationale and Organizational Aspects
Primary Angioplasty Vs. Fibrinolysis: An Overview of Randomized Trials and Registry Data	p. 1
Which Patients Should Be Transferred for Primary PCI?	p. 11
Pharmacological Facilitation in Primary Angioplasty: Myth or Reality?	p. 22
How to Organize Networks for Invasive Treatment of STEMI: Krakow Experience?	p. 30
How to Organize Networks for Invasive Treatment of STEMI: The Zwolle Experience	p. 36
How to Organize Networks for Invasive Treatment of STEMI: Linköping Experience	p. 41
How to Organize Networks for Invasive Treatment of STEMI: Experience in the United States	p. 50
How to Organize Networks for Invasive Treatment of STEMI: Experience in Asia	p. 56
Failed Thrombolysis: Rescue Angioplasty or Conservative Therapy?	p. 59
Primary PCI in Cardiogenic Shock and Out-of-Hospital Cardiac Arrest	p. 66
Adjunctive Pharmacotherapy
Oral Antiplatelet Therapy	p. 73
Glycoprotein IIb/IIIa Inhibitors	p. 83
Anticoagulation Therapy	p. 94
Technical Aspects
Balloon Angioplasty or BMS?	p. 103
Drug-Eluting Stent: Weighing Costs and Benefits	p. 114
Mechanical Prevention of Distal Embolization: Rationale and Trials Results	p. 123
Distal Protection Devices: Tips and Tricks	p. 137
Thrombectomy Devices: Tips and Tricks	p. 144
Proximal Devices: Tips and Tricks	p. 152
Hemodynamic Support in High-Risk Patients	p. 162
Limitation of Infarct Size: Adjunctive Mechanical Devices	p. 170
Transradial Access for Primary PCI: Advantages Beyond any Doubt	p. 180
Intravascular Imaging: IVUS, OCT, and Angioscopy	p. 189
Redefining the Success of Mechanical Reperfusion
Redefining the Success of Mechanical Reperfusion: ST-Segment Resolution	p. 197
Redefining the Success of Mechanical Reperfusion: TIMI Flow and Myocardial Blush	p. 203
Redefining the Success of Mechanical Reperfusion: Doppler Flow-Wire	p. 215
Redefining the Success of Mechanical Reperfusion: Cardiac MRI	p. 221
Redefining the Success of Mechanical Reperfusion: Contrast Echocardiography	p. 227
Redefining the Success of Mechanical Reperfusion: Nuclear Techniques	p. 234
Special Issues
Bleeding Complications in Patients Undergoing Percutaneous Coronary Intervention: Prognostic Implications and Prevention	p. 240
Contrast-Induced Nephropathy in Patients Undergoing Primary Angioplasty: Prognostic Implications, Prevention, and Management	p. 250
A Glimpse into the Future
Myocardial Regeneration: Cell-Therapy After Reperfusion in Patients with ST-Elevation Myocardial Infarction	p. 259
Early Discharge After Primary PCI	p. 267
Guidelines
ACC/AHA and ESC Guidelines	p. 274
Index	p. 281
Table of Contents provided by Ingram. All Rights Reserved.

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Mechanical Reperfusion for STEMI: From Randomized Trials to Clinical Practice

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