Mechanochemistry Principles, Methods and Applications

Filling a huge gap and bridging the knowledge between the various subdisciplines, this is a well-structured overview for both beginners and more advanced researchers in academia and industry. The two experienced and excellent scientist authors include many applications, so that readers can see how the theories are applied in real life.
A must-have for many inorganic and organic chemists, material and life scientists, as well as pharmaceutical developers.

Professor Jonathan W. Steed has published ca. 250 papers, which have been cited over 5000 times, giving him a citations H-factor of 36. He is co-author of two textbooks (Supramolecular Chemistry, Wiley, 2000 & 2nd ed. 2009, and Core Concepts in Supramolecular Chemistry and Nanochemistry, Wiley, 2007) and has co-edited the Encyclopaedia of Supramolecular Chemistry (Dekker, 2004), Organic Nanostructures (Wiley-VCH, 2008) and a six-volume work Supramolecular Chemistry from Molecules to Nanomaterials (in preparation for 2011). He has received numerous awards in research and education, including the Royal Society of Chemistry Corday-Morgan Prize 2010, the Bob Hay Lectureship (2008), Vice Chancellor's Award for Excellence in Doctoral Supervision (2006) and the Royal Society of Chemistry Meldola Medal (1998).

Doctor Tomislav Friscic has co-authored over 70 articles in the areas of solid-state organic and metal-organic chemistry, photochemistry, pharmaceutical materials science and crystal engineering, which were cited well over a 1000 times leading to citations H-factor of 21. Following undergraduate education in Croatia (Zagreb), doctoral degree in the USA (Iowa) and a postdoctoral appointment at the Pfizer Institute for Pharmaceutical Materials Science (Cambridge, UK), he is currently a Herchel Smith Research Fellow in Materials Chemistry at the University of Cambridge and is also a Fellow of the Sidney Sussex College where he organises popular science seminars on the interaction of humans with the environment.

INTRODUCTION
definitions and history
advantages
green chemistry
solvent-free chemistry
solvent-limited chemistry
energy-limited chemistry
biochemical context

METHODS AND INSTRUMENTS
Manual methods
Mechanically activated ageing
Grinder mills
Planetary mills
Screw extrusion
Equipment choice, design and manufacture

CHARACTERISATION
Diffraction techniques
Spectroscopic techniques
Thermal analysis

MECHANISMS
Stepwise mechanisms
Formation of intermediatesTopological considerations
Amorphous phase formation
Thermodynamic rationalisations/phase diagram interpretations

ADVANCED METHODS AND CATALYSIS
Catalysis
Liquid-assisted grinding (LAG)
Ion- and liquid-assisted grinding (ILAG)
Grinding-annealing techniques

ORGANIC SYNTHESIS
Different types of organic reactions
Approaches - stepwise and single-step (one-pot) synthesis

METAL-ORGANIC SYNTHESIS AND METAL-ORGANIC FRAMEWORKS (MOFS)
Design
Small molecules
Linear and sheet polymers
Porous and non-porous MOFs
Zeolitic imidazolate frameworks
Porosity and functional behaviour
Mechanisms and mechanochemical interconversion of porous/non-porous topologies

SUPRAMOLECULAR SYNTHESIS
Design
Molecular recognition: cocrystals, inclusion complexes
One-pot multiple recognition and molecular assembly process
Solid-state self-assembly: small molecules and molecular cages
Computational/theoretical approaches

INORGANIC SYNTHESIS
Design
Mixed salts and oxides
Composite materials
Alloying
Nano-sized materials

COMPARISON TO RELATED TECHNIQUES
Sonochemistry
Microwave synthesis

PHARMACEUTICAL AND INDUSTRIAL APPLICATIONS
Solid forms
Cocrystals
Salts
Screening
Scaling-up methods

RELATED SOLID-STATE METHODOLOGIES
Topochemistry
Photochemical solid-state reactions
Thermochemical solid-state reactions
Gas-solid reactions
Microscopic methods: nanoscratching and nanoindentation

SELECTED PRACTICAL PREPARATIVE EXPERIMENTS
Supramolecular
Metal-organic
Organic
Inorganic