Metabolic Syndrome and Neurological Disorders

Metabolic Syndrome and Neurological Disorders brings together information on the cluster of common pathologies which cause metabolic syndrome - abdominal obesity linked to an excess of visceral fat, insulin resistance, dyslipidemia and hypertension - to provide a comprehensive and cutting edge exploration of the link between metabolic syndrome and neurological disorders.

Metabolic syndrome is recognized to play a role in neurological disorders such as stroke, Alzheimer's disease, and depression. For the first time in book form, Metabolic Syndrome and Neurological Disorders covers the molecular mechanisms thought to underlie this mirror relationship, as well as how lifestyle and other factors such as oxidative stress and inflammation may play a role in the disease. Grounded in a series of epidemiological studies of metabolic-cognitive syndrome, this book will be a valuable reference for researchers, dietitians, nutritionists, and physicians.

TAHIRA FAROOQUI is a Research Scientist in the Department of Entomology at Ohio State University. She is the author of 40 peer-reviewed research articles and several monographs and an expert on glycerophospholipid and sphingolipid metabolism, biogenic amines, and neural plasticity.

Chapter 1 Insulin resistance and metabolic failure underlie Alzheimer’s disease
Suzanne M. de la Monte & Ming Tong

Chapter 2 Insulin receptor and the pathophysiology of Alzheimer’s disease
Johanna Zemva & Markus Schubert

Chapter 3 Contribution of insulin resistance in pathogenesis of Alzheimer’s disease
Adnan Erol

Chapter 4 Insulin-leptin signaling in the brain
Vicente Barrios, Emma Burgos-Ramos & Jesús Argente

Chapter 5 The janus face of insulin in brain
Duarte AI, Candeias E, Correia SC, Santos RX, Carvalho C, Cardoso S, Plácido AI, Santos MS, Oliveira CR, Moreira PI

Chapter 6 Modulation of cognition by insulin and aging: implications for Alzheimer disease
Maite Solas & Maria J Ramírez

Chapter 7 Contribution of phospholipid, sphingolipids, and cholesterol-derived lipid mediators in the pathogenesis of metabolic syndrome and neurological disorders
Akhlaq A. Farooqui & Tahira Farooqui

Chapter 8 Lipids, cholesterol and oxidized cholesterol in Alzheimer’s Amyloid Beta-mediated neurotoxicity
Mun’delanji Vestergaard, Masamune Morita, Tsutomu Hamada & Masahiro Takagi

Chapter 9 Of sound mind and body: dietary lifestyles, promotion of healthy brain aging and prevention of dementia in healthy individuals
Giulio Maria Pasinetti, Amanda Bilski, Lap Ho, Jun Wang, Mario Ferruzzi, Masahito Yamada, Kenjiro Ono, & Salvatore Mannino

Chapter 10 Metabolic syndrome as an independent risk factor of silent brain infarction
Jae-Sung Lim & Hyung-Min Kwon

Chapter 11 Neurochemical linkage among metabolic Syndrome, Alzheimer’s disease, and depression
Undurti N Das

Chapter 12  Alterations in the endocannabinoid system as a link between unbalanced energy homeostasis, neuroinflammation and neurological and neuropsychiatric disorders
Tiziana Bisogno & Vincenzo Di Marzo

Chapter 13 Metabolic syndrome, Alzheimer’s disease, schizophrenia and depression: Role for leptin, melatonin, kynurenine pathways and  neuropeptides
George Anderson & Michael Maes

Chapter 14 Binge eating and metabolic syndrome
Ignacio Jáuregui-Lobera

Chapter 15 Phytochemical principles in the traditional Indian system of medicine used for the management of metabolic syndrome
Syed Ibrahim Rizvi & Neetu Mishra

Chapter 16 Oxidative stress and obesity: their impact on metabolic syndrome
Morihiro Matsuda & Iichiro Shimomura

Chapter 17 Relationship between obesity, inflammation, and insulin resistance
Jean-Philippe Bastard & Bruno Fève

Chapter 18 Involvement of adipocytokines in pathogenesis of insulin resistance, obesity and metabolic syndrome
Hardik Gandhi & Ramachandran Balaraman

Chapter 19 Obesity, inflammation and vascular disease: novel insight in the role of adipose tissue
Calabrò P, Golia E, Maddaloni V, Limongelli G, Ziello B, Fimiani F, Romano IJ, Crisci M, Russo MG, Yeh ETH, & Calabrò R

Chapter 20 Is diabetes as a risk factor for Parkinsons diseases?
Akhlaq Farooqui & Tahira Farooqui

Chapter 21 Role of iron in the pathogenesis of diabetes and metabolic syndrome
Lu Cai

Chapter 22 Contributions of AMP kinase to the Pathogenesis of Type 2 Diabetes and Neurodegenerative Diseases
Mohamed Kodiha, Hicham Mahboubi & Ursula Stochaj

Chapter 23 Aβ deposition, insulin signaling and tau phosphorylation in animal models of Alzheimer disease and diabetes
Naoyuki Sato & Ryuichi Morishita

Chapter 24 In vivo Evidence of the convergence of type-2 diabetes and Alzheimer’s disease
Sun Ah Park

Chapter 25 Metabolic syndrome and its impact on cardiovascular disease
John Larry

Chapter 26 Contribution of inflammation, adiponectin, and obesity in cardiovascular diseases
Harald Mangge & Gunter Almer

Chapter 27 Brain and cardiovascular diseases: molecular aspects
Ewa Szczepanska-Sadowska

Chapter 28 Molecular aspects of dietary–exercise regimen for the prevention of metabolic syndrome
Wataru Aoi

Chapter 29 Ghrelin, lipid metabolism and metabolic syndrome 
Pablo B. Martínez de Morentin, Sulay Tovar, Rubén Nogueiras, Miguel López & Carlos Diéguez

Chapter 30 Leptin and cognitive Function
Jenni Harvey

Chapter 31 Fructose, sugar consumption, and metabolic diseases
Virgile Lecoultre & Luc Tappy

Chapter 32 Inflammation-mediated cognitive and emotional alterations in experimental models of metabolic syndrome
Nathalie Castanon & Sophie Layé

Chapter 33 Future perspectives
Tahira Farooqui & Akhlaq A. Farooqui 

The New copy of this book will include any supplemental materials advertised. Please check the title of the book to determine if it should include any access cards, study guides, lab manuals, CDs, etc.

The Used, Rental and eBook copies of this book are not guaranteed to include any supplemental materials. Typically, only the book itself is included. This is true even if the title states it includes any access cards, study guides, lab manuals, CDs, etc.