Metallothionein IV

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ISBN: 9783764358303 | 3764358300
Cover: Hardcover
Copyright: 1/1/1999

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The Proceedings of the Fourth International Metallothionein Meeting (M T-97) feature the latest research on metallothionein. The book covers a broad range of topics which provide important information for both b asic and clinical investigators. The selected 94 articles in this book are written by the leading scientists in the field around the world. This is an increasingly important, multi-disciplinary area of study th at has benefitted from recent advances in concepts and methodologies f rom other fields.

List of contributors

Metallothionein nomenclature and structure

Nomenclature of metallothionein: Proposal for a revision

(4)

Yutaka Kojima

Pierre-Alain Binz

Jeremias H.R. Kagi

Metallothionein: Molecular evolution and classification

(8)

Pierre-Alain Binz

Jeremias H.R. Kagi

Structural and biological studies on native bovine Cu, Zn-metallothionein-3

(8)

Milan Vasak

Ralf Bogumil

Peter Faller

Daniel W. Hasler

Pierre-Alain Binz

Stefan Klauser

Arend Bruinink

John M. Charnock

C. David Garner

Circular Dichroism, emission, and exafs studies of Ag(I), Cd(II), Cu(I), and Hg(II) binding to metallothioneins and modeling the metal binding site

(14)

Martin J. Stillman

Anna Rae Green

Ziqi Gui

David Fowle

P. Anthony Presta

Metallothionein structure update

(8)

Gulin Oz

Dean L. Pountney

Ian M. Armitage

Simulation of Zn/Cd binding in mammalian metallothionein domains

(6)

C.C. Chang

P.C. Huang

The growth inhibitory activity of metallothionein-3 correlates with its novel β domain sequence rather than metal binding properties

(4)

Laran T. Jensen

Jay C. Erickson

Richard D. Palmiter

Dennis R. Winge

Recombinant synthesis and metal-binding abilities of mouse metallothionein 1 and its α- and β-domains

(8)

Silvia Atrian

Roger Bofill

Merce Capdevila

Neus Cols

Pilar Gonzalez-Duarte

Roser Gonzalez-Duarte

Angels Leiva

Oscar Palacios

Nuria Romero-Isart

Biochemical characterization of monomeric and dimeric cadmium-substituted metallothionein-3

(10)

Peep Palumaa

Rain Lehtme

Chemical and analytical aspects of metallothionein

Mammalian metallothionein sub-isoform separation by RP-HPLC with on-line UV and electrochemical detection

(12)

Guy Bordin

Fernando Cordeiro Raposo

Adela Rodriguez

Characterisation of mammalian Cd, Zn metallothioneins using differential pulse polarography

(8)

Adela Rosa Rodriguez

Comparison of CZE and MECC separations of MT isoforms

(6)

Vesa Virtanen

Guy Bordin

Synthetic peptides and domains of metallothionein for structure function studies: rabbit liver peptide MT-IIA 49-61 and lobster MT βN βC and βC→N domains

(12)

Amalia munoz

Frank Laib

Eugene DeRose

David H. Petering

John Ejnik

C. Frank Shaw III

Voltammetric methods in isolation and identification of plant metallothioneins from alga Chlorella

111

(6)

Ivana Sestakova

Pavel Mader

Hana Vodickova

Vira Pacakova

Characterization of isometallothineins in Chang liver cells and the transient accumulation of metallothionein and glutathione during cell proliferation

117

(8)

Annemarie Willi

Peter E. Hunziker

Quantification of cytosolic metallothionein contents by a developed assay system using immobilized antibody

125

(4)

Tomomi Nagashima

Masashi Okabe

Shigeru Saito

Masaaki Kurasaki

Toshitsugu Hirauchi

Shinzo Kimura

Tadashi Niioka

Protein engineering of metallothionein to study on the metal-binding ability

129

(8)

Masaaki Kurasaki

Futoshi Yamasaki

Rie Yamaguchi

Ana Rosa Linde Arias

Masashi Okabe

Tadasu Emoto

Fumitomo Odawara

Mika Suzuki-Kurasaki

Shigeru Saito

Yutaka Kojima

Metal binding proteins: Molecular engineering of improvements in metal specificity

137

(8)

Ian Watt

Peter Kille

Molecular splicing of metallothionein - study on domains of metallothionein

145

(12)

Yi Xiong

Yanjiao Zhou

Yiwu Chen

Binggen Ru

Metallothionein in non-mammalian tissues

Involvement of metallothionein in female squirrelfish reproduction

157

(10)

E.D. Thompson

P.-E. Olsson

G.D. Mayer

C. Haux

P. Walsh

C. Hogstrand

Accumulation of untranslated metallothionein mRNA in antarctic hemoglobinless fish (icefish)

167

(6)

Vincenzo Carginale

Rosaria Scudiero

Antonio Capasso

Clemente Capasso

Gianluca Passaretti

Guido di Prisco

Peter Kille

Elio Parisi

Structure and function of metallothionein isoforms in terrestrial snails

173

(6)

Reinhard Dallinger

Burkhard Berger

Peter Hunziker

Jeremias H.R. Kagi

Functional and regulatory aspects of teleost metallothionein

179

(8)

P.-E. Olsson

M. Gerpe

P. Kling

Metallothionein induction in mussels exposed to a metal mixture

187

(8)

M.J. Bebianno

W.J. Langston

Synthesis and properties of class III metallothioneins of Schizosaccharomyces pombe in response to cadmium and zinc

195

(6)

Mary M. Lauro

Donald J. Plocke

Phytochelatins (class III metallothioneins) and their desglycyl peptides induced by cadmium in root cultures of Rubia tinctorum L.

201

(6)

Tamio Maitani

Hiroki Kubota

Kyoko Sato

Takashi Yamada

Chemical and spectroscopic properties of copper metallothionein from the copper resistant fungus Beauveria bassiana

207

(8)

Satomi Kameo

Peter Faller

Milan Vasak

Yutaka Kojima

Transcription factors

Metallothionein facts and frustrations

215

(8)

Richard D. Palmiter

Liver degeneration and embryonic lethality in mouse null mutants for the metal-responsive transcriptional activator MTF-1

223

(4)

Cagatay Gunes

Rainer Heuchel

Oleg Georgiev

Karl-Heinz Muller

Silvia Marino

Adriano Aguzzi

Horst Bluthmann

Walter Schaffner

New insights into the mechanisms of cadmium regulation of mouse metallothionein I gene expression

227

(6)

G.K. Andrews

D. Bittel

T. Dalton

N. Hu

W. Chu

M. Daggett

Q. Li

J. Johnson

Activation of mouse metallothionein I promoter by cadmium in human neuroblastoma cells

233

(4)

Jeffrey A. Johnson

Jeffrey D. Moehlenkamp

Waihei Chu

Douglas Bittel

Glen K. Andrews

Transcription factors involved in heavy metal regulation of the human metallothionein-IIA gene

237

(6)

Shinji Koizumi

Yasumitsu Ogra

Kaoru Suzuki

Fuminori Otsuka

Transcriptional regulation of the gene encoding mouse metallothionein-3 and its expression in the organs of the reproductive system

243

(8)

Pierre Moffatt

Raffaella Faraonio

Olivier LaRochelle

Isabelle Delisle

Rene Saint-Arnaud

and Carl Seguin

Dynamic regulation of yeast metallothionein gene transcription via metalloregulatory signaling factors

251

(2)

D.J. Thiele

M.M.O. Pena

K.A. Koch

Metal regulation of mammalian metal responsive element (MRE) binding proteins

253

(8)

L. Gedamu

S.L.-A. Samson

S. Schieman

W. Paramchuk

Metallothionein and hormone responsiveness

261

(6)

James Koropatnick

Janice M. DeMoor

Olga M. Collins

Synergistic activation of mouse metallothionein-I gene by interleukin-6 and glucocorticoid

267

(6)

Norio Itoh

Keiko Kasutani

Masako Kanekiyo

Tomoki Kimura

Norio Muto

Keiichi Tanaka

Hammerhead ribozymes mediated down-regulation of rat metallothionein mrnas expression

273

(8)

Kai-Fai Lee

Shuk-Mei Ho

Inactivation of metal-induced metallothionein gene expression by protein kinase C inhibitor

281

(6)

Je-Hsin Chen

Chih-Wen Yu

Lih-Yuan Lin

Cadmium-induced metallothionein expression and metallothionein mRNA in mice

287

(4)

Keiji Suzuki

Kyoumi Nakazato

Katsuyuki Nakajima

Role of metallothionein in reproduction, development and cell proliferation

The nuclear-cytoplasmic presence of metallothionein in cells during differentiation and development

291

(4)

M. George Cherian

John C. Lau

Margarita D. Apostolova

Lu Cai

Metallothionein and male genital organs

295

(6)

Chiharu Tohyama

Junko S. Suzuki

Hisao Nishimura

Noriko Nishimura

Induction of metallothionein-like cadmium binding protein in testis and its protective role against cadmium toxicity

301

(8)

H. Ohta

H. Tanaka

S. Asami

Y. Seki

H. Yoshikawa

Zinc homeostasis during pregnancy in metallothionein-null mice on a low zinc diet

309

(6)

A.M. Rofe

J.C. Philcox

M. Sturkenboom

P. Coyle

Restriction of cadmium transfer to egg from laying hen exposed to cadmium: Involvement of metallothionein in the ovaries

315

(6)

Shin Sato

Masashi Okabe

Tadasu Emoto

Masaaki Kurasaki

Yutaka Kojima

Metallothionein expression during wool follicle development in foetal sheep

321

(4)

Hisao Nishimura

Noriko Nishimura

Chiharu Tohyama

Graham R. Cam

David L. Adelson

A role of hepatic metallothionein on mercury distribution in fetal guinea pigs after in utero exposure to mercury vapor

325

(8)

Minoru Yoshida

Hiroshi Satoh

Yawara Sumi

Cell differentiation alters metallothionein expression in avian growth plate chondrocytes

333

(8)

Glenn R. Sauer

Licia N. Y. Wu

Daotai Nie

Roy E. Wuthier

Metallothionein in brain disease

Metallothionein in oxidate stress of Parkinson's disease

341

(10)

Manuchair Ebadi

Midori Hiramatsu

M.V. Ramana Kumari

Ruyi Hao

Ronald F. Pfeiffer

Metallothionein-1,2 and heme oxygenase-1 are expressed in damaged brain regions following chemically-induced seizures

351

(8)

Mitchell R. Emerson

Robert S. Cross

Shaohua Jin

Fred E. Samson

Thomas L. Pazdernik

Molecular cloning and expression of the metallothionein (MT)-I and MT-III in brain lesions of dogs

359

(4)

Akinori Shimada

Seiji Kojima

Takashi Uemura

Yoshiaki Yamano

Kinji Kobayashi

Takehito Morita

Takashi Umemura

Liver and brain metallothionein regulation in transgenic mice overexpressing interleukin-6 and in mice carrying a null mutation in the interleukin-6 gene

363

(8)

Juan Hidalgo

Javier Carrasco

Joaquin Hernandez

Mercedes Giralt

Amalia Molinero

Berta Gonzalez

Horst Bluethmann

Iain L. Campbell

Effects of capsaicin on metallothionein (MT) mRNA in sensory neurons: Possible role of MT-III in nociception

371

(6)

Yongjiu Cai

Ruben A. Velazquez

Alice A. Larson

Metallothionein expression in the mammalian brain

377

(6)

Adrian K. West

Adele F. Holloway

Fiona A. Stennard

Janine M. Miller

Induction of metallothionein-I (MT-I) mRNA in primary astrocyte cultures is mediated by hypotonicity

383

(6)

M. Aschner

and D.R Conklin

Metallothionein in the cerebral cortex of rats showing hereditary high ability in sidman avoidance test

389

(8)

H. Aikawa

T. Yoshida

H. Ohta

Y. Seki

Role of metallothionein in copper metabolism, diabetes and autoimmune disease

Roles of metallothionein in the cytotoxicity of copper in the liver of LEC rats

397

(6)

Kazuo T. Suzuki

Ming Rui

Jun-ichi Ueda

Toshihiko Ozawa

Fate of copper and metallothionein in the liver of LEC rats

403

(10)

Dominik Klein

Josef Lichtmannegger

Ulrich Heinzmann

Josef Muller-Hocker

Karl H. Summer

Relationship between Cu metabolism hereditary disorders and distribution of Cu-metallothionein in kidneys

413

(8)

Masashi Okabe

Shigeru Saito

Mika Suzuki-Kurasaki

Takeshi Saito

Akira Hata

Fumio Endo

Koji Nagano

Ken-ichi Urakami

Ichiro Matsuda

Masaaki Kurasaki

Zincsulphate protects from streptozotocin-induced diabetes mellitus in mice: a function of metallothionein?

421

(8)

Patricia Ohly

Zhiyong Wang

Claudia Dohle

Josef Abel

Helga Gleichmann

MT does not protect endocrine cell damage induced by alloxan in pancreas of mice

429

(4)

Takeshi Minami

Hidenori Tanaka

Yuko Okazaki

Setsuko Tohno

Yoshiyuki Tohno

Plasma MT levels in diabetic and renal failure patients

433

(4)

Takeshi Minami

Setsuko Tohno

Yoshiyuki Tohno

Noriko Otaki

Masami Kimura

M. George Cherian

Metallothionein-mediated alterations in autoimmune disease processes

437

(8)

M.A. Lynes

C.A. Richardson

R. McCabe

K.C. Crowthers

J.C. Lee

J. Youn

I.B. Schweitzer

L.D. Shultz

Dietary zinc, Photoimmunosuppression and metallothionein (MT)

445

(8)

Vivienne E. Reeve

Noriko Nishimura

Meira Bosnic

Andy K. H. Choo

Anna E. Michalska

Role of metallothionein in Cd-induced nephrotoxicity and bone loss

Metallothionein-null mice are susceptible to chronic CdCl2-induced nephropathy: Cd-induced renal injury is not necessarily mediated by CdMT

453

(6)

Curtis D. Klaassen

Jie Liu

Yaping Liu

Sultan S. Habeebu

Cellular metallothionein: Properties of apometallothionein and the comparative toxicity of Cd2+ and Cd-metallothionein

459

(8)

David H. Petering

Munira Dughish

Meilin Huang

Susan Krezoski

Sara Krull

Donna Lewand

Amalia Munoz

Lifen Ren

Sudha Venkatesh

Samuel Blumenthal

C. Frank Shaw III

Zinc-induced protection against cadmium-metallothionein nephrotoxicity depends on glutathione status

467

(4)

Zahir A. Shaikh

Weifeng Tang

Selma Sadovic

Mechanism of improved cadmium-induced renal dysfunction after cessation of cadmium exposure

471

(2)

Kazuo Nomiyama

Hiroko Nomiyama

Naoki Kameda

The role of metallothionein in cadmium-induced bone resorption

473

(4)

Maryka H. Bhattacharyya

Carmen A. Blum

Allison K. Wilson

Metallothionein induction in human proximal tubular cell cultures-lack of protection against heavy metal toxicity

477

(8)

Adrian T. Miles

Vicente Rodilla

Antony G. Breen

John Beattie

William Jenner

Gabrielle M. Hawksworth

Relationship of metallothionein to cadmium and to zinc in human liver and kidney

485

(4)

Arata Teranishi

Ruriko Ninomiya

Naoko Koizumi

Apoptosis of human kidney 293 cells is promoted by polymerized Cd-metallothionein

489

(10)

Tetsuo Hamada

Akihide Tanimoto

Takakazu Sasaguri

Nobuyuki Arima

Shohei Shimajiri

Ryuji Nakano

Yasuyuki Sasaguri

Role of metallothionein in oxidative stress

Subcellular localization mediated functioning of metallothionein: Protection against oxygen radicals and anticancer agents

499

(6)

Elizabeth S. Woo

Bruce R. Pitt

John S. Lazo

Obesity and hyperleptinemia in a colony of metallothionein (-I and -II) null mice

505

(6)

John H. Beattie

Anne M. Wood

April M. Newman

Ian Bremner

K.H.

Anna E. Michalska

Jackie S. Duncan

Paul Trayhurn

Cardiac protection by metallothionein against ischemia-reperfusion injury and its possible relation to ischemic preconditioning

511

(6)

Y. James Kang

Ju-Feng Wang

Metallothionein and its importance relative to glutathione in cardiac protection against doxorubicin toxicity

517

(6)

Guang-Wu Wang

Hui-Yun Wu

Y. James Kang

Metallothionein metal composition is a determinant of its induction of the mitochondrial permeability transition

523

(6)

Cuthbert O. Simpkins

Tracy Lloyd

Sai Li

Samuel C. Balderman

Protective effect of metallothionein on DNA damage induced by hydrogen peroxide and ferric ion-nitrilotriacetic acid

529

(6)

Kyong-Son Min

Kayo Nishida

Yukiko Nakahara

Satomi Onosaka

Effect of metallothionein on cardiac reperfusion injury in rats

535

(6)

Seiki Minamide

Masashi Okamoto

Fumio Naganuma

Katsuyuki Nakajima

Tadashi Suzuki

Susceptibility to metals and radical-inducing chemicals of metallothionein-null mice

541

(6)

Masahiko Satoh

Chiharu Tohyama

Metallothionein-I/II knockout mice are sensitive to acetaminophen-induced hepatotoxicity

547

(6)

Jie Liu

Yaping Liu

Curtis D. Klaassen

Stacey E. Shehin-Johnson

Angela Lucas

Steven D. Cohen

Effect of oxidative stress and bioavailable zinc on metallothionein in cultured human retinal pigment epithelial cells (RPE)

553

(8)

David J. Tate Jr.

Michael V. Miceli

David A. Newsome

Specific binding sites of metallothionein on endothelium of small vessels in myocardium

561

(8)

Shi Cheng

Ge Shujun

Zhong Chongxia

He Qihua

Hou Lin

Metallothionein and carcinogenesis

Further studies on the role of metallothionein in the antitumor effects of cadmium

569

(4)

Michael P. Waalkes

Takeaki Nagamine

Hideaki Shimada

Bhalchandra A. Diwan

Timothy P. Coogan

Noriyuki Shiraishi

M. George Cherian

Robert A. Goyer

Effects of metallothionein expression on development of drug resistance

573

(4)

Toby G. Rossman

Ekaterina I. Goncharova

A chemical mechanism for inactivation of anticancer drugs by metallothionein Catherine Fenselau

577

(4)

Miquel D. Antoine

Daniele Fabris

Yetrib Hathout

Tao He

Joseph Zaia

The possible role of metallothionein in cancer therapy by copper acetate

581

(4)

Qing Huai

Xingwang Fang

Jilan Wu

Wenquing Wang

Guojian Huang

Shu Zhou

Interaction of metallothionein with the carcinogenic metals Ni(II), Cr(VI) and As(III)

585

(10)

Dean E. Wilcox

Laura L. Bennett

Elizabeth H. Cox

George Haleblian

Brian T. Hill Eric P. Kowack

Xiaoyan Liu

Jane S. Merkel

Amy E. Palmer

Matthew C. Posewitz

Joann E. Roy

karen E. Wetterhahn

A novel metallothionein gene therapy approach for chemo-and radio-protection Tupur Husain

595

(6)

Asim B. Abdel-Mageed

Alan M. Miller

Laura S. Levy

Krishna C. Agrawal

Metallothionein immunostaining as a prognostic indicator in canine mammary tumours

601

(6)

I. Carmen Fuentealba

Julia E. Mullins

Metallothionein isoform gene expression in four human bladder cancer cell lines

607

(6)

Scott H. Garrett

Seema Somji

John H. Todd

Donald A. Sens

Donald L. Lamm

Mary Ann Sens

The suppression of metallothionein synthesis inhibits the growth of leukemia P388 cells

613

(8)

Atsushi Takeda

Harumi Hisada

Shoji Okada

John E. Mata

Patric L. Iversen

Manuchair Ebadi

Metallothioneins as biomarkers

Identification and characterisation of metallothioneins from environmental indicator species as potential biomonitors

621

(8)

Ceri A. Morris

Stephen Sturzenbaum

Beate Nicolaus

A. John Morgan

John L. Harwood

Peter Kille

Assessment of metal exposure of marine edible mussels by means of a biomarker

629

(4)

Biserka Raspor

Jasenka Pavicic

Sonja Kozar

Zelijko Kwokal

Marina Paic

Niksa Odzak

Irena Ujevic

Zorana Kljakovic

Metallothionein level estimation in the bioassay method for water quality assessment in freshwater reservoirs polluted by waste waters

633

(8)

Dasha A. Avramova

Boris I. Synsynys

Valentina A. Romantsova

Gennady M. Rott

Subject index

641

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Metallothionein IV

Summary

Table of Contents

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