Microbial Pathogenesis and the Intestinal

Univ. of Illinois, Chicago. Reviews and analyzes current data on the impact of pathogens upon intestinal host cells. Examines the effects of enteric microbial pathogens on host intestinal epithelial cell function and physiology. Covers the normal structure and function of the gastrointestinal tract. For researchers. DNLM: Intestinal Diseases--microbiology.

Contributors

ix

Preface

xiii

Functional Morphology of the Intestinal Mucosae: from Crypts to Tips

1

(22)

Jerrold R. Turner

Role of Intestinal M Cells in Microbial Pathogenesis

23

(20)

Marian R. Neutra

Philippe Sansonetti

Jean-Pierre Kraehenbuhl

Intestinal Immunity

43

(18)

Iris Dotan

Lloyd Mayer

Cytokines and Epithelial Function

61

(18)

Sean P. Colgan

Glenn T. Furuta

Cormac T. Taylor

Role of Toll-Like Receptors in Innate Immunity of the Intestine

79

(16)

Elke Cario

Daniel K. Podolsky

Intestinal Immunoglobulin A: Role in Host Defense

95

(18)

Jiri Mestecky

Michael W. Russell

Sequence-Based Methods for Investigating Intestinal Microbes

113

(8)

David N. Fredricks

Application of Microarray Analysis to the Investigation of Host-Pathogen Interactions

121

(20)

Dawn A. Israel

Richard M. Peek, Jr.

Pathogen-Initiated Inflammatory Response in Intestinal Epithelial Cells: Cross Talk with Neutrophils

141

(14)

Andrew T. Gewirtz

Shanti V. Sitaraman

Didier Merlin

James L. Madara

Upregulation of Innate Defense Mechanisms by Enteric Infections

155

(20)

Martin F. Kagnoff

Microbial Interference with Host Inflammatory Responses

175

(16)

Andrew S. Neish

Antimicrobial Peptide Effectors of Small Intestinal Innate Immunity

191

(32)

Andre J. Ouellette

Michael E. Selsted

Role of Commensal Enteric Bacteria in Intestinal Inflammation: Lessons from Animal Models

223

(18)

R. Balfour Sartor

Physiological Regulation of Gastrointestinal Ion Transport

241

(26)

Kim E. Barrett

Lone S. Bertelsen

Epithelial Response to Enteric Pathogens: Activation of Chloride Secretory Pathways

267

(18)

V. K. Viswanathan

Gail Hecht

Enteric Pathogens That Affect Intestinal Epithelial Tight Junctions

285

(16)

Gail Hecht

Enteric Microbial Toxins and the Intestinal Epithelial Cytoskeleton

301

(32)

James P. Nataro

Cynthia Sears

Alessio Fasano

Robert J. Bloch

Ontogeny of the Host Response to Enteric Microbial Infection

333

(18)

Bobby J. Cherayil

W. Allan Walker

Neuroimmune Interactions and Pathogenesis of Intestinal Inflammation in Infectious Diseases

351

(16)

Charalabos Pothoulakis

Apoptosis and Enteric Bacterial Infections

367

(18)

Barbel Raupach

Arturo Zychlinsky

Trafficking of Cholera Toxin and Related Bacterial Enterotoxins: Pathways and Endpoints

385

(18)

Chiara Rodighiero

Wayne I. Lencer

Type III Secretion Systems of Enteric Bacterial Pathogens

403

(20)

Catherine A. Lee

How Noninvasive Pathogens Induce Disease: Lessons from Enteropathogenic and Enterohemorrhagic Escherichia coli

423

(16)

Bruce A. Vallance

Crystal Chan

B. Brett Finlay

Salmonella spp.: Masters of Inflammation

439

(16)

Beth A. McCormick

Effector Molecules of Shigella Pathogenesis and Host Responses

455

(26)

M. Isabel Fernandez

Philippe J. Sansonetti

Toxins of Vibrio cholerae: Consensus and Controversy

481

(22)

Karla Jean Fullner

Pathogenicity of Clostridium difficile Toxins

503

(22)

Michel Warny

Ciaran P. Kelly

Viral Pathogens of the Intestine

525

(22)

Mary K. Estes

Robert L. Atmar

Index

547

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Microbial Pathogenesis and the Intestinal Epithelial Cell

Summary

Table of Contents

Supplemental Materials

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Microbial Pathogenesis and the Intestinal Epithelial Cell

Summary

Table of Contents

Supplemental Materials

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