Modern Fluoroorganic Chemistry Synthesis, Reactivity, Applications

For the second edition, this book has been completely revised and updated, as well as enlarged to reflect the latest developments in synthetic organic fluorine chemistry, plus novel applications in materials science and medicinal chemistry. In addition, new chapters have been added on such important applications as organic electronics (LEDs) and fluorinated dyes. A valuable reference for fluorine chemists while also providing non-specialists with an introduction to the field.

Peer Kirsch is the Director of Emerging Technologies at Merck KGaA in Darmstadt, Germany. Having obtained his PhD in chemistry at Heidelberg University and the Max Planck Institute for Medical Research working with Prof. Dr. Heinz A. Staab in 1993, he spent two years as a postdoctoral researcher at the Institute of Physical and Chemical Research (RIKEN) in Wako, Japan, before he joined Merck in 1995. He worked on the design and synthesis of liquid crystals for LCD applications for 10 years, with a strong focus on fluoroorganic synthesis and computational property prediction. From 2005 to 2010 he worked for Merck Ltd. Japan in various functions. Since 2009 Peer Kirsch is a visiting professor at the University of Bremen and he teaches also at the University of Freiburg since 2011. He has authored more than 45 scientific publications as well as more than 140 patents. His main research interests include the application of fluoroorganic chemistry, molecular modelling and combinatorial methods for the design and synthesis of highly fluorinated liquid crystals and other advanced materials.

INTRODUCTION
Why Organofluorine Chemistry
History
The Basic Materials
The Unique Properties of Organofluorine Compounds

SYNTHESIS OF COMPLEX ORGANOFLUORINE COMPOUNDS
Introduction of Fluorine
Perfluoroalkylation
Special Fluorinated Structures and Reaction Types
The Chemistry of Highly Fluorinated Olefins

FLUOROUS CHEMISTRY
Fluorous Biphasic Catalysis
Fluorous Synthesis and Combinatorial Chemistry

APPLICATIONS OF ORGANOFLUORINE COMPOUNDS
Halofluorocarbons, Hydrofluorocarbons and Related Compounds
Polymers and Lubricants
Applications in Electronics Industry
Liquid Crystals For Active Matrix LCDs
Pharmaceuticals and Other Biomedical Applications
Agricultural Chemistry
Fluorine in Organic Electronics *New*
Fluorinated Dyes *New*

APPENDIX
Typical Synthetic Procedures
Index of Synthetic Conversions