Modified-Release Drug Delivery Technology, Second Edition

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ISBN: 9781420044355 | 1420044354
Cover: Hardcover
Copyright: 5/28/2008

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This two volume Second Editiondescribes the anatomical, physiological, pharmaceutical, and technological aspects of oral, colonic and rectal, ocular, oral mucosal, dermal and transdermal, nasal, vaginal, and pulmonary delivery routes, providing insight and critical assessment of the many available and emerging modified release drug delivery systems for their current and future value. Topics include:

Preface	p. v
Contributors	p. xi
Intellectual Property Rights
Patent and Other Intellectual Property Rights in Drug Delivery	p. 1
Intellectual Property Developments and Issues in India	p. 27
Parameter Claims at the European Patent Office	p. 33
Japan's Patent Issues Relating to Modified Drug Delivery Technology	p. 45
Oral Mucosal Technologies
Oral Transmucosal Drug Delivery	p. 53
Pilocarpine Buccal Insert	p. 75
OraVescent Drug Delivery System: A Novel Technology for the Transmucosal Delivery of Drugs	p. 83
DentiPath Development	p. 93
Medicated Chewing Gum	p. 101
The Oral PowderJect Device for Mucosal Drug Delivery	p. 113
The PerioChip: A Biodegradable Device for the Controlled Delivery of Chlorhexidine in the Subgingival Environment	p. 121
Oral Technologies
Modified-Release Delivery Systems for Oral Use	p. 131
Advances in Cellulose Ether-Based Modified-Release Technologies	p. 143
SQZgel	p. 153
Thiolated Polymers for Controlled Release	p. 163
Two Concepts, One Technology: Controlled-Release Solid Dispersions Using Melt Extrusion (Meltrex)	p. 179
Threeform-Technology for Controlled Release of Amorphous Active Ingredient for Once-Daily Administration	p. 187
Floating Gastroretentive Capsule for Controlled Drug Delivery	p. 197
Thin Film Oral Dosage Forms	p. 209
Dose Sipping Technology-A Novel Dosage Form for the Administration of Drugs	p. 217
Enhanced Gastroretentive Dosage Form with Minimal Food Effects: GIRES	p. 231
Advancing Gastrointestinal Permeation Enhancement Formulations into the Clinic: GIPET	p. 239
The Micropump Technology	p. 251
A Novel Microparticle Technology for Tailored Drug Release in the Gastrointestinal Tract	p. 261
Lipid Nanoparticles (SLN, NLC, LDC) for the Enhancement of Oral Absorption	p. 269
Colonic Technologies
Colonic Drug Delivery	p. 287
Biopolymers and Colonic Delivery	p. 295
Enteric Coating for Colonic Delivery	p. 311
Programmed Drug Delivery Systems and the Colon	p. 325
Pulsincap and Hydrophilic Sandwich Capsules: Innovative Time-Delayed Oral Drug Delivery Technologies	p. 337
Targeting the Colon Using COLAL: A Novel Bacteria-Sensitive Drug Delivery System	p. 343
Development of the Egalet Technology	p. 349
Regulatory Issues and Challenges
Regulatory Aspects in Modified-Release Drug Delivery	p. 357
Regulatory Issues in the United States Relating to Modified-Release Drug Formulations	p. 385
Japanese Regulatory Issues on Modified-Release Drug Products	p. 421
Regulatory Aspects of Delivery Systems in the European Union	p. 437
Canadian Regulatory Requirements for Drug Approval	p. 459
Regulating Modified-Release Drug Delivery Technologies in Australia	p. 473
Index	p. 487
Table of Contents provided by Ingram. All Rights Reserved.

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Modified-Release Drug Delivery Technology, Second Edition

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