Modified-Release Drug Delivery Technology, Second Edition

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ISBN: 9781420053562 | 1420053566
Cover: Hardcover
Copyright: 5/28/2008

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This two volume Second Editiondescribes the anatomical, physiological, pharmaceutical, and technological aspects of oral, colonic and rectal, ocular, oral mucosal, dermal and transdermal, nasal, vaginal, and pulmonary delivery routes, providing insight and critical assessment of the many available and emerging modified release drug delivery systems for their current and future value. Topics include:

Introduction (The Modified Drug Release Landscape)
The Modified Drug Release Landscape: Academic Viewpoint
The Modified Drug Release Landscape: Regulatory Viewpoint
The Modified Drug Release Landscape: Intellectual Property Viewpoint
Using Modified Release Formulations to Maintain and Develop Markets
Maintenance and Development of Markets
Approaches That Satisfy the Patients' Needs
Approaches That Satisfy the Doctors' Needs
Approaches That Satisfy the Innovators' Needs
The Need of the Investor
Oral
Introduction
Osmotic Systems
Qtrol
Qdis
Matrix Systems
SQZgel
Thiolated Polymers for CR
Oradur
IDD Technology
Chronotherapy Technology
Meltrex
Threeform
Floating Capsule
Cast Films for Oral Use
Monolithic and Composite Matrices for Modified Release Drug
Delivery in Single or Multiple Drug Therapy
Dissocubes
Dose Sipping Technology
GIPET, GIRES
Micropump
Colonic and Rectal
Introduction
Test Systems for Colonic Devices
Enteric Coating for Colonic Delivery
Biopolymers and Colonic Delivery
Time-dependent Systems for Colonic Delivery
Pulsincap and Hydrophilic Sandwich (HS) Capsules
Egalet Technology
Ocular
Introduction
Ophthalmic Drug Delivery
Ocular Inserts
Intraocular Implants
Ion Exchange Resin Technology for Ophthalmic Applications
I-vation Sustained Release Intravitreal System
Oral Mucosal
Introduction
Oral-lyn (RapidMist Technology)
Buccal Drug Delivery System
ORAVESCENT: A Novel Technology for the Transmucosal Delivery of Drugs
Medichew Technology Platform
DentiPatch
Medicated Chewing Gum
The BEMA Drug Delivery Technology
Oral Transmucosal System (OTS)
Dermal and Transdermal
Introduction
ALZA Technologies (E-Trans, D-Trans, Macroflux, etc.)
Metered Dose Transdermal Spray Technology
Microneedles for Drug Delivery
Transdermal Delivery
Transfersomes
Recent Advances in Wound Healing
Ultrasound in Transdermal Delivery
SLN and Lipopearls
Iontophoretic Delivery
Radiofrequency Technology
The PassPort System
Novel Polymers for Dermal and Transdermal Delivery
Nail Delivery
NanoCyte Technology
Noven Transdermal Technology
Injections and Implants
Introduction
Long Acting Protein Formulations
Duros Implant
Sucrose Acetate Isobutyrate (SAIB) for Parenteral Delivery
Particulate Injectors and Imprinter
ReGel
The Atrigel Drug Delivery System
Depofoam
Medusa
Alzamer
Stealth Technology
Nasal
Introduction
ViaNase Intranasal Device and Controlled Particle Dispersion Technology Platform
Single and Multidose Devices for the Delivery of Liquid and Dry Powder Drug Formulations
DirectHaler Nasal
Chitosan
Vaginal
Introduction
Intravaginal Ring Systems
Supravail
Vagisite
C-Vad Vaginal Insert
'Smart' Vaginal Delivery Systems
Pulmonary
Introduction
The AERx Pulmonary Drug Delivery System
Formulation Challenges of Powders for the Delivery of Small Molecular Weight Molecules as Aerosols
AAD-Adaptive Aerosol Delivery Technology
Nebulizer Technologies
MicroDose Propietary Dry Powder Inhaler
Formulation Challenges: Protein Powders for Inhalation
The RESPIMAT, A New Soft Mist Inhaler for Delivering Drugs to the Lungs
Metered Dose Inhalation Technology
Intellectual Property
US Intellectual Property Issues Relating to Modified Release Products
India Intellectual Property Issues Relating to Modified Release Products
Germany Intellectual Property Issues Relating to Modified Release Products
Japan Intellectual Property Issues Relating to Modified Release Products
Regulatory Issues Relating to Modified Release Drug Formulations
USA (FDA)
Japan (PMDA)
Australia and New Zealand
Catalog Copy
Table of Contents provided by Publisher. All Rights Reserved.

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Modified-Release Drug Delivery Technology, Second Edition

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Table of Contents

Supplemental Materials