Molecular Approaches to Reproductive and Newborn Medicine

(preliminary)

Section 1: Molecular Aspects of Reproductive Development and Gametogenesis
1. MicroRNA in Ovarian Biology and Disease
Lynda K. McGinnis, Lacey J. Luense and Lane K. Christenson
2. Confrontation, Consolidation, and Recognition: The Oocyte's Perspective on the Incoming Sperm
David Miller
3. Intergenerational Transfer of Epigenetic Information in Sperm
Oliver J. Rando
4. HOX Genes and Female Reproduction
Hongling Du and Hugh S. Taylor

Section 2: Molecular Aspects of Fertilization and Implantation
5. Human Endometrial Transcriptomics: Implications for Embryonic Implantation
E. Gomez, M. Ruiz-Alonso, Jose Miravet and C. Simón
6. A Molecular Perspective on Procedures and Outcomes Associated with Assisted Reproductive Technologies
Monica A. Mainigi, Carmen Sapienza, Samantha Butts and Christos Coutifaris

Section 3: Molecular Aspects of Placental Development
7. Molecular Cross-Talk at the Feto-Maternal Interface
Gendie E. Lash
8. Placental Extracellular Vesicles and Feto-Maternal Communication
M. Tong and L.W. Chamley
9. The Function of TrophomiRs and Other MicroRNAs in the Human Placenta
Yoel Sadovsky, Jean-Francois Mouillet, Yingshi Ouyang, Avraham Bayer and Carolyn B. Coyne
10. The Human Placental Methylome
Wendy P. Robinson and E. Magda Price

Section 4: Molecular Aspects of Normal Pregnancy and Delivery
11. The Perinatal Microbiome and Pregnancy: Moving Beyond the Vaginal Microbiome
Amanda L. Prince, Derrick M. Chu, Maxim D. Seferovic, Kathleen M. Antony, Jun Ma and Kjersti M. Aagaard
12. Molecular Regulation of Parturition: A Myometrial Perspective
Nora E. Renthal, Koriand'r C. Williams, Alina P. Montalbano, Chien-Cheng Chen and Carole R. Mendelson
13. Molecular Regulation of Parturition: The Role of the Decidual Clock
Errol R. Norwitz, Elizabeth A. Bonney, Victoria V. Snegovskikh, Michelle A. Williams, Mark Phillippe, Joong Shin Park and Vikki M. Abrahams

Section 5: Molecular Aspects of Abnormal Pregnancy
14. Genetic Considerations in Recurrent Pregnancy Loss
Kassie J. Hyde and Danny J. Schust
15. Genomics of Preterm Birth
Kayleigh A. Swaggart, Mihaela Pavlicev and Louis J. Muglia
16. Molecular Mechanisms of Preeclampsia
Tammy Hod, Ana Sofia Cerdeira and S. Ananth Karumanchi
17. Molecular Approaches to the Effects of Maternal Obesity
Caterina Neri and Andrea G. Edlow

Section 6: Prenatal Molecular Screening and Diagnosis
18. Noninvasive Prenatal Screening for Genetic Diseases Using Massively Parallel Sequencing of Maternal Plasma DNA
Lyn S. Chitty and Y.M. Dennis Lo
19. Noninvasive Antenatal Determination of Fetal Blood Group Using Next Generation Sequencing
Klaus Rieneck, Frederik Banch Clausen and Morten Hanefeld Dziegiel
20. Genome-Wide Sequencing for Prenatal Detection of Fetal Single-Gene Disorders
Ignatia B. Van den Veyver and Christine M. Eng
21. The Amniotic Fluid Transcriptome as a Guide to Understanding Fetal Disease
Lillian M. Zwemer and Diana W. Bianchi

Section 7: Molecular Approaches to Diagnosis of Disease in the Neonate
22. Potential Uses and Inherent Challenges of Using Genome-Scale Sequencing to Augment Current Newborn Screening
Jonathan Berg and Cynthia M. Powell
23. Whole Exome and Whole Genome Sequencing in Critically Ill Neonates Suspected to Have Single Gene Disorders
Laurie D. Smith, Laurel K. Willig, Emily G. Farrow, Sarah E. Soden, Joshua E. Petrikin, Isabelle Thiffault, Carol J. Saunders, and Stephen F. Kingsmore
24. The Neonatal Salivary Transcriptome
Jill L. Maron

Index