Molecular Mechanisms of Immunological Self-Recognition

, by Alt, Fredrick W.; Vogel, Henry J.

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ISBN: 9780120537501 | 0120537508
Cover: Hardcover
Copyright: 1/1/1993

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Preface
Introduction
Immunological Tolerance Revisited in the Molecular Era
B Cell Tolerance
Mechanisms and Meaning of B Lymphocyte Tolerance
Tolerant Autoreactive B Lymphocytes in the Follicular Mantle Zone Compartment: Substrates for Receptor Editing and Reform
Lymphocyte Signaling
T Cell Anergy
The T Cell Antigen Receptor: Biochemical Aspects of Signal Transduction
Structure and Signaling Function of B Cell Antigen Receptors of Different Classes
T Cell Tolerance
Self-Nonself Discrimination by T Lymphocytes
Transgenic Mouse Model of Lymphocyte Development
Recognition Requirements for the Positive Selection of the T Cell Repertoire: A Role of Self-Peptides and Major Histocompatibility Complex Pockets
Mechanisms of Peripheral Tolerance
An Analysis of T Cell Receptor-Ligand Interaction Using a Transgenic Antigen Model for T Cell Tolerance and T Cell Receptor Mutagenesis
T Cell Repertoire and Tolerance
Sequential Occurrence of Positive and Negative Selection during T Lymphocyte Maturation
Tolerance Induction in the Peripheral Immune System
Autoimmunity
Activation-Induced Cell Death of Effector T Cells: A Third Mechanism of Immune Tolerance
T Cells Involved in Inductive Events in the Pathogenesis of Autoimmune Diabetes Melitus
Genetic Control of Diabetes and Insulitis in the Nonobese Diabetic Mouse: Analysis of the NOD.H-2[subscript b] and B10.H-2[superscript nod] Strains
Islet Tolerance in Humans and Transgenic Mice
Fluorescence-Activated Cell Sorter Analysis of Peptide-Major Histocompatibility Complex
Tolerance to Self: A Delicate Balance
Prevention, Suppression, and Treatment of Experimental Autoimmune Encephalomyelitis with a Synthetic T Cel Receptor V Region Peptide
Perspectives
Tolerance of Self: Present and Future
Index
Table of Contents provided by Blackwell. All Rights Reserved.

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Molecular Mechanisms of Immunological Self-Recognition

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