Neurostimulation Principles and Practice

Could neurostimulation be a management option for your patients?

Neurostimulation techniques present real management options for patients with a range of neurologic and psychiatric disorders, such as movement disorders, pain and depression. They should be actively considered when conventional medical approaches have failed or are inappropriate. But for many clinicians, these new methods pose many questions. What are the available modalities? How do they work? Which patients might benefit from them? How do I explain the processes to patients? How do I monitor my patient’s progress after implantation?
Neurostimulation provides a concise, easy-to-read fusion of the clinical applications of implanted neurostimulators. It demystifies selection and referral criteria, maximizing therapy, programming the implanted neuromodulators, monitoring progress and troubleshooting problems associated with neurostimulation.
Written by an international cast of experts, Neurostimulation, sets the stage for you to provide real clinical benefit to your patients who might receive, or are already using, neurostimulators.

Edited by
Sam Eljamel, MBBCh, MD, FRCSEd, FRCSIr, FRCS(SN), Department of Neurosurgery, Ninewells Hospital and Dundee Medical School, Dundee, UK

Konstantin Slavin, MD, FAANS, Department of Neurosurgery, University of Illinois at Chicago, Chicago, IL, USA

List of Contributors

Preface

Part 1: Deep Brain Stimulation

Chapter 1: Deep Brain Stimulation (DBS) mechanisms of action
Erwin B. Montgomery Jr. MD, Alabama, USA

Chapter 2: Overview of DBS components
M. Sam Eljamel, MD, FRCSEd, FRCSIre (SN), Dundee, Scotland

Chapter 3: DBS in Parkinson’s disease (PD): Subthalamic nucleus (STN) DBS
Manish Ranjan, MBBS, MCh and Christopher R. Honey, MD, DPhil, FRCS(C)

Chapter 4: Pallidal (GPi) DBS
Yasuaki Harasaki, MD, and Steven Ojemann, MD, Denver, USA

Chapter  5: DBS of the Pedunculopontine Nucleus (PPN) for PD
Aviva Abosch, MD, PhD and Amit Goyal, MD, Minnesota, USA

Chapter 6: DBS in Tremor
Antonios Mammis, MD and Michael Schulder, MD New York, USA

Chapter 7: Deep Brain Stimulation in Dystonia
Ludvic Zrinzo MD PhD FRCSEd (NeuroSurg), London, UK

Chapter 8: DBS in Epilepsy
Michael G. Kaplitt, MD PhD, New York, USA

Chapter 9: DBS in obsessive compulsive disorders (OCD)
David Christmas, PhD, Dundee, Scotland and Loes Gabriëls, PhD, Leuven, Belgium

Chapter 10: DBS in treatment refractory major depression (TRMD)
Clement Hamani, MD, PhD, Toronto, Canada and  Paul E. Holtzheimer, III, MD Lebanon, NH,USA

Chapter 11: DBS in pain syndromes
Alexander Green, FRCS(SN), MD, BSc, Oxford, UK

Chapter 12:DBS in Cluster Headache
Giovanni Broggi, MD, Giuseppe Messina, MD, Angelo Franzini, MD, Milan, Italy

Part 2: Vagus nerve stimulation (VNS)

Chapter 13: Mechanism of action and overview of VNS technology
Sam Eljamel, MBBCh, MD, FRCSIr, FRCSEd, FRCS(SN), Dundee, Scotland

Chapter 14: VNS in Epilepsy
Ian Morrison PhD, MRCP (UK), Dundee, UK

Chapter 15: VNS in TRMD
Christine Matthews, Serenella Tolomeo, Keith Matthews, PhD, Dundee

Part 3: Motor Cortex Stimulation (MCS)

Chapter 16: Mechanism of action and overview of MCS components
M. Sam Eljamel, MD, FRCSEd, FRCSIre (SN), Dundee, Scotland

Chapter 17: MCS in refractory pain
Giovanni Broggi, MD, Giuseppe Messina, MD, Roberto Cordella PhD, Angelo Franzini, MD, Milan, Italy

Part 4: Spinal Cord Stimulation (SCS)

Chapter 18: Mechanism of action and Overview of SCS components
M. Sam Eljamel, MD, FRCSEd, FRCSIre (SN), Dundee, Scotland

Chapter 19: SCS in Failed Back Surgery Syndrome (FBSS)
Gail Gillespie  and Pravin Dandegaonkar, Dundee, Scotland

Chapter 20: SCS in complex regional pain syndrome (CRPS)
Eduardo Goellner, MD, Porto Alegre, Brazil, & Konstantin Slavin, MD, FAANS, Chicago, USA

Chapter 21: SCS in other indications
Konstantin V. Slavin, MD, FAANS, Chicago, USA and Sam Eljamel, MD, FRCS(Ed),(Ir),(SN), Dundee, Scotland

Part 5: Peripheral nerve stimulation (PNS)

Chapter 22: PNS in Head and Face Pain
Konstantin V. Slavin, MD, FAANS, Chicago, Illinois, Serge Y. Rasskazoff, MD, FRCS(C), Flint, Michigan, Sami Al-Nafi, MD, Chicago, Illinois

Chapter 23: PNS in Pain of the Body and Extremities
Konstantin V. Slavin, MD, FAANS, Chicago, Illinois, Sami Al-Nafi, MD, Chicago, Illinois, Serge Y. Rasskazoff, MD, FRCS(C), Flint, Michigan

Appendices

Appendix I: Principles of programming of neurostimulators
Sam Eljamel, MD, FRCS(Ed,Ir,SN), Patrick Carena, BSc, Catherine Young, RCN, Dundee, Scotland

Appendix II: Troubleshooting malfunctioning neurostimulators
Sam Eljamel, MD, FRCS(Ed,Ir,SN), Dundee, Scotland

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