Nucleoside Mimetics: Their Chemistry and Biological Properties

Nucleosides exhibit a broad spectrum of biological activity that generally results from their ability to inhibit specific enzymes. This activity has led to their use in the development of various pharmaceutical agents used in the treatment of cancers and to combat harmful viruses, bacteria and parasites.Nucleoside Mimetics provides an introduction to the chemistry of nucleoside mimetics, which combines carbohydrate, heterocyclic and asymmetric synthesis. The book gives a comprehensive introduction to nucleosides and coverage of the various classes. The aim of Nucleoside Mimetics is to provide the reader with a useful insight into the diversity of nucleosides, the range of elegant chemistry involved and the continuing importance of nucleosides as both therapeutic agents and as probes for studying biochemical processes.

Claire Simons is a lecturer at the Welsh School of Pharmacy, Cardiff University, UK. Her main research interests are the design and synthesis of novel heterocyclic and nucleoside compounds as enzyme inhibitors, carbohydrate methodology and the isolation and preparation of natural products