Obesity And Mental Disorders

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ISBN: 9780824729448 | 0824729447
Cover: Hardcover
Copyright: 1/13/2006

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Currently, there are a limited amount of guidelines to help clinicians manage patients with obesity and comorbid mental disorders. This expertly written source fills the gap in the literature by providing a clear overview of obesity and its relationship to mental illness while reviewing the most recent methods to manage and control the condition with diet, exercise, psychological treatments, pharmacotherapy, and surgery.

Preface

iii

Contributors

PART I: OVERVIEW OF OBESITY

1. Obesity Is a Major Health Problem: Causes and Natural History

(20)

George A. Bray

Overview of Obesity

(3)

The Causes of Obesity

(12)

References

(5)

PART II: RELATIONSHIP BETWEEN OBESITY AND PSYCHOPATHOLOGY

2. Obesity and Psychotic Disorders

(20)

Jogin H. Thakore and Leona Spelman

Introduction

(1)

Mortality Studies in Schizophrenia

(1)

Morbidity from General Medical Disease in Schizophrenia

(1)

Cardiovascular Risk Factors and Schizophrenia

(1)

Obesity and Schizophrenia

(1)

Visceral Fat Distribution and Schizophrenia

(2)

Potential Reasons for Excess Intra-Abdominal Fat Distribution in First-Episode Schizophrenia

(1)

Prediabetes and Type 2 Diabetes and Schizophrenia

(3)

Potential Reasons for Increased Prevalence of Type 2 Diabetes in First-Episode Schizophrenia

(2)

Summary

(1)

References

(7)

3. Obesity and Mood Disorders

(52)

Susan L. McElroy, Renu Kotwal, Erik B. Nelson, Shishuka Malhotra, Paul E. Keck Jr., and Charles B. Nemeroff

Epidemiology of Obesity and Mood Disorders: A Brief Overview

(3)

Clinical Studies of Mood Disorders in Patients with Obesity

(4)

Community Studies of Mood Disorders in Obesity

(4)

Studies of Obesity in Mood Disorders

(1)

Clinical Studies of Obesity in Mood Disorders

(5)

Community Studies of Obesity in Mood Disorders

(3)

Phenomenology

(2)

Course of Mood Symptoms and Weight Change

(1)

Comorbidity

(2)

Family History

(2)

Neurobiology

(1)

Response to Treatment: Pharmacotherapy

(3)

Conclusion

(4)

References

(16)

4. Eating Disorders in Obesity

(10)

L.K. George Hsu

Binge Eating Disorder

(5)

Night Eating Syndrome

(1)

References

(5)

5. Obesity and Substance Use Disorders

103

(20)

Mark S. Gold, Helen C. Oppenheirn, and Kimberly Frost-Pineda

Introduction

103

(1)

Eating Disorders/Substance Abuse Comorbidity

104

(4)

Neurotransmitters and Peptides

108

(3)

The Process of Addiction

111

(5)

Conclusions

116

(1)

References

116

(7)

6. Obesity and Smoking

123

(22)

Jaimee L. Heffner, Suzan Winders-Barrett, and Robert M Anthenelli

Smoking and Weight Gain

125

(4)

Interventions to Prevent or Reduce Weight Gain Following Smoking Cessation

129

(9)

Conclusions and Recommendations for Further Research

138

(2)

References

140

(5)

7. Obesity and Impulsive and Compulsive Disorders

145

(20)

Latha V. Soorya, Bryann R. Baker, Lisa Sharma, and Eric Hollander

Introduction

145

(2)

Obsessive Compulsive Disorder

147

(1)

Body Dysmorphic Disorder

147

(1)

Eating Disorders

148

(2)

Impulse-Control Disorders and Borderline Personality Disorder

150

(3)

Developmental Disorders

153

(4)

Summary

157

(1)

Reference

158

(7)

8. Metabolic Syndrome: Overview and Relationship with Psychiatric Disorders

165

(24)

Richard A. Bermudes and Anna Guerdjikova

Introduction

165

(1)

Defining Features of the Metabolic Syndrome

166

(1)

Significance of Metabolic Syndrome

166

(2)

Pathophysiology of Metabolic Syndrome The Role of Visceral Obesity

168

(2)

Visceral Fat and Glucose Intolerance

170

(1)

Visceral Fat and Dyslipidemia

170

(1)

Visceral Fat and Elevated Blood Pressure

170

(1)

Magnitude of the Problem

171

(2)

The Metabolic Syndrome in Psychiatric Populations

173

(1)

Metabolic Abnormalities in Psychiatric Patients

173

(2)

Psychiatric Treatments and Metabolic Abnormalities

175

(2)

Monitoring for the Metabolic Syndrome in Psychiatric Settings

177

(2)

Treatment Recommendations

179

(2)

Summary

181

(1)

References

181

(8)

9. Obesity, Polycystic Ovary Syndrome, and Mood Disorders

189

Margaret F. Reynolds and Natalie L. Rasgon

Introduction

189

(1)

The Metabolic Syndrome: Obesity and IR

190

(3)

Overview of Mood Disorders: Bipolar Disorder and Major Depressive Disorder

193

(2)

Polycystic Ovary Syndrome: The Interface of Obesity, Mood Disorders, and IR

195

(14)

References

209

(8)

PART III: BEHAVIORAL TREATMENTS OF OBESITY WITH AND WITHOUT PSYCHOPATHOLOGY

10. Dietary Therapy of Obesity

217

(18)

Robert F. Kushner and Bethany Doerfler

Introduction

217

(1)

Dietary Assessment

218

(4)

The Dietary Prescription

222

(1)

Strategies for Dietary Counseling

223

(7)

Team Approach

230

(1)

Conclusion

231

(1)

References

231

(4)

11. Behavioral Weight Management of Obese Patients with Mental Disorders

235

(26)

Susan L. McElroy and Renu Kotwal

Behavioral Weight Management in the Treatment of Obesity

235

(1)

Goals of Behavioral Weight Management in the Treatment of Obesity

236

(6)

Behavioral Weight Management of Obesity with Mental Disorders

242

(11)

References

253

(8)

PART IV: MEDICAL TREATMENTS OF OBESITY WITH AND WITHOUT PSYCHOPATHOLOGY

12. Pharmacologic Agents in the Treatment of Obesity

261

(28)

Donna H. Ryan

Introduction

261

(2)

Drugs Approved by the FDA with an Indication for Weight Management

263

(12)

Medications Used in Obesity Management, but Which Do Not Have an FDA-Approved Indication

275

(6)

Future Directions

281

(2)

Summary

283

(1)

References

284

(5)

13. Overview of Agents with Efficacy in Binge Eating

289

(18)

Jose C. Appolinario and Josué Bacaltchuk

Introduction

289

(2)

Antidepressants

291

(2)

Opioid Antagonists

293

(1)

Anti-Obesity Agents

294

(1)

Anticonvulsants

295

(2)

Other Agents

297

(1)

Combined Treatment

298

(1)

Augmentation Strategies

299

(1)

Comments

300

(1)

Conclusions

301

(1)

References

302

(5)

14. Psychotropic-Induced Weight Gain: Liability, Mechanisms and Treatment Approaches

307

(48)

Roger S. McIntyre, Jakub Z. Konarski, and Paul E. Keck Jr.

Introduction

307

(2)

Medication-Associated Weight Gain: Liability

309

(15)

Medication-Associated Weight Gain: Mechanisms

324

(7)

Prevention and Treatment of Medication-Associated Weight Gain

331

(6)

Summary

337

(1)

References

337

(18)

15. Medical Management of Uncomplicated Obesity

355

(14)

Jonathan A. Waitman and Louis J. Aronne

Introduction

355

(3)

Sibutramine (Meridia)

358

(1)

Orlistat (Xenical)

359

(1)

Phentermine

360

(1)

Available Drugs that Cause Weight Loss

361

(2)

Drugs Currently in Clinical Trials

363

(1)

Medication-Induced Obesity

364

(1)

Conclusion

364

(1)

References

364

(5)

16. Medical Management of Obesity Associated with Mood Disorders

369

(48)

Susan L. McElroy, Renu Kotwal, and Paul E. Keck Jr.

Introduction

369

(1)

Obesity and Mood Disorders: A Brief Overview

370

(2)

Comorbidity as a Marker for Mood Disorder

372

(4)

Therapeutic Profiles of Psychotropic and Anti-Obesity Drugs

376

(1)

Therapeutic and Appetite/Weight Profiles of Psychotropics Used in Mood Disorder

377

(12)

Anti-Obesity Drugs in Mood and Related Disorders

389

(1)

Response to Combination Treatment

390

(1)

Assessment of the Patient with Obesity and a Mood Disorder

390

(1)

Obesity and Depressive Disorders

391

(1)

Obesity and Bipolar Disorders

392

(2)

Conclusion

394

(1)

References

394

(23)

17. Medical Management of Obesity and Binge Eating

417

(6)

Scott Crow and Kerry Wangen

Approach to the Patient with Binge Eating Disorder

418

(1)

Mood and Anxiety Disorders

419

(1)

Psychotic and Bipolar Disorders

420

(1)

Duration of Treatment for Binge Eating

421

(1)

References

422

(1)

18. Weight Loss Surgery for the Treatment of Morbid Obesity

423

(10)

Reena Bhargava, Calvin Selwyn, and Keith S. Gersin

Introduction

423

(1)

History

424

(3)

Surgical Criteria

427

(2)

Surgical Risks

429

(1)

Conclusion

430

(1)

References

431

(2)

19. The Role of Bariatric Surgery in the Obese Patient with Psychopathology

433

(22)

James E. Mitchell, Tricia Cook Myers, Lorraine Swan-Kremeier, and Martina de Zwaan

Introduction

433

(1)

Psychopathology Contraindications

434

(3)

Screening Bariatric Surgery Candidates for Psychopathology

437

(1)

Psychiatric Interview

438

(1)

Rates of Psychopathology

439

(2)

Psychopathology Rates at Follow-Up

441

(3)

Impact of Psychopathology on Outcome

444

(3)

Treatment of Comorbid Psychopathology

447

(2)

Summary

449

(1)

References

449

(6)

Index

455

(8)

About the Editors

463

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Obesity And Mental Disorders

Summary

Table of Contents

Supplemental Materials