Oxygen Creating a New Paradigm

• Describes how oxygen and its reactive derivatives can damage vital cell components, and how oxygen plays a pivotal role in the damaging effects of inflammation, radiation, and aging.
• Challenges the traditional notion that oxygen delivery is the principal function of the cardiorespiratory system, and that oxygen transport is the principal function of red blood cells and hemoglobin.
• Demonstrates how the tissues normally operate in an oxygen-poor environment (which limits the risk of oxidative damage), and how the body counteracts attempts to increase tissue oxygenation.
• Describes the body’s use of protective antioxidants, and shows how failure to maintain this antioxidant protection makes oxygen inhalation an unrecognized source of harm.
• Reveals the lack of evidence that cellular hypoxia is a final common pathway for cell death, and proposes that oxygen itself is responsible for the death of aerobic organisms.
• Proposes a new management strategy that is “oxygen-protective” rather than “oxygen-promoting.”

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