Parkinson's Disease: Diagnosis and Clinical Management

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ISBN: 9781933864006 | 1933864001
Cover: Hardcover
Copyright: 11/1/2007

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Parkinson's disease (PD) is the second most common neurodegenerative disease in the world. Still the only major text on the subject, the completely revised and updated second edition of Parkinson s Disease: Diagnosis and Clinical Management comes at a tim

James Parkinson: The Man and the Essay	p. 3
Paralysis Agitans in the Nineteenth Century	p. 15
Charcot and Parkinson's Disease	p. 21
Timeline of Parkinson's Disease History Since 1900	p. 33
Epidemiology	p. 39
Cardinal Features of Early Parkinson's Disease	p. 45
Gait Disturbances	p. 55
Sensory Symptoms	p. 65
Voice, Speech, and Swallowing Disorders	p. 77
Gastrointestinal Features	p. 99
Autonomic Dysfunction	p. 107
Sleep Disorders	p. 119
Natural History	p. 127
Clinical Rating Scales	p. 135
Dementia	p. 147
Depression	p. 159
Anxiety and Panic	p. 179
Apathy and Amotivation	p. 189
Impulse-control Disorders	p. 201
Neuropathology	p. 213
Neurochemistry	p. 227
Basal Ganglia: Anatomy and Physiology	p. 245
Dopamine Receptor Diversity	p. 267
Status of Biological Markers	p. 277
Positron Emission Tomography	p. 285
Single Photon Emission Computed Tomography	p. 293
Magnetic Resonance Imaging	p. 305
Controversies in Neuroimaging	p. 317
Animal Models	p. 329
Pathogenesis: Oxidative Stress, Mitochondrial Dysfunction, and Excitotoxicity	p. 341
The Concept and Mechanisms of Programmed Cell Death	p. 357
Protein Aggregation	p. 373
Etiology: The Role of Environment and Genetics	p. 387
The Impact of MPTP on Parkinson's Disease Research: Past, Present, and Future	p. 407
Rotenone and Other Toxins	p. 437
Inflammation	p. 449
Genetics	p. 455
Levodopa: A Pharmacologic Miracle Four Decades Later	p. 471
Amantadine and Anticholinergics	p. 491
Monoamine Oxidase Inhibitors	p. 499
Dopamine Agonists	p. 515
Catechol-O-Methyltransferase Inhibitors	p. 533
Excitatory Amino Acid Antagonists	p. 545
Adenosine A[subscript 2A] Receptor Antagonists	p. 557
Complementary and Alternative Medicine	p. 563
Motor Fluctuations and Dyskinesia	p. 575
Fluctuations of Nonmotor Symptoms	p. 585
Psychosis and Other Behaviors	p. 593
Treatment of Dementia	p. 613
Status of Neuroprotective Therapies	p. 619
Symptomatic Treatment Approaches for Early Parkinson's Disease	p. 633
Progress in Gene Therapy	p. 643
Genetic Testing	p. 655
Deep Brain Stimulation	p. 663
Neural Transplantation: Yesterday, Today, and Tomorrow	p. 689
Stereotactic Pallidotomy and Thalamotomy	p. 699
Parkinson's-plus Disorders	p. 727
Symptomatic Parkinsonism	p. 741
Outcome Measures	p. 751
Family Caregiving	p. 759
Economics	p. 771
Driving	p. 779
The Patient's Perspective	p. 791
Table of Contents provided by Blackwell. All Rights Reserved.

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Parkinson's Disease: Diagnosis and Clinical Management

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