Pharmaceutical Emulsions and Suspensions: Second Edition, Revised and Expanded

Covering fundamental and applied knowledge of pharmaceutical emulsions and suspensions, this volume begins with theoretical considerations concerning pharmaceutical surfactants, formulation concepts, and emulsion properties and how to attain them. Basic concepts are covered first, including thermodynamic and kinetic aspects of suspension formulations and the physiochemical properties leading to the stability of these systems. Health applications are then covered, including emulsions as drug delivery systems, parenteral fat emulsions, vesicles as a tool for dermal and transdermal drug delivery, ophthalmic emulsions and suspensions, the administration of emulsions to the gastrointestinal tract, dry absorbed emulsions, and nanosuspensions for poorly soluble drugs. Finally, tools and methods for experiments and measurements are covered, including theoretical aspects of experimental design in emulsion and suspension formulation, rheology of suspensions and emulsions, and the determination of size distributions of submicrometer particle dispersions by photon correlation spectroscopy.