About the Editors Contributors Preface Preface to the First Edition Acknowledgments SECTION 1 Principles of Clinical Research Chapter 1 The Scientific Approach to Research and Practice Chapter 2 Ethical Considerations in Clinical Research Chapter 3 Research Design and Methods Chapter 4 Randomized-Controlled Trials Chapter 5 Cohort and Case-Control Studies Chapter 6 Other Observational Studies Chapter 7 Case Reports and Case Series SECTION 2 Statistical Principles and Data Analysis Chapter 8 Measurement and Descriptive Analysis Chapter 9 Interpretation and Basic Statistical Concepts Chapter 10 Bivariate Analysis and Comparing Groups Chapter 11 Simple and Multiple Linear Regression Chapter 12 Logistic Regression and Survival Analysis Chapter 13 Sample Size and Power Analysis Chapter 14 Systematic Review and Meta-Analysis SECTION 3 Principles of Drug Literature Evaluation Chapter 15 Principles of Evidence-Based Medicine Chapter 16 Introduction to Drug Literature Chapter 17 Evaluating Clinical Literature: An Overview Chapter 18 Evaluating Randomized Controlled Trials Chapter 19 Evaluating Observational Studies Chapter 20 Evaluating Qualitative Research Studies Chapter 21 Applying Drug Literature to Patient Care Chapter 22 Basics of Journal Club Appendix A Glossary Index
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